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Pharm Ch 5 - HCCRT
Pharm Ch 5 - CNS & PNS - HCCRT
Question | Answer |
---|---|
Receptor Blockage | The blockage of receptor stimulation and it's effects. |
Enzyme Inhibition | The interference with the production of certain mechanism-enabling enzymes. |
What are the components of the CNS? | Brain & Spinal Cord |
What are the components of the PNS? | Inludes sensory, sympathetic and parasympathetic nerves. |
AcH - Acetylocholine | A chemical produced by the body that is used in the transmission of nerve impulses. It is destroyed by the enzyme cholinesterase. |
What neurons lack snapses so they go directly from the CNS to the sensory reception site? | Sensory & Motor |
What are the neuromuscular blocking agents? | Pavulon & Curare |
Anticholinergic | Refers to a drug blocking a receptor for acetylcholine. |
Ganglion | Mass of nervous tissue composed primarily of the neuro cell bodies & lying outside the brain or spinal cord. |
Efferent Nerve Fibers | Impulses that go away from the CNS to the various body parts. |
Afferent Nerve Fibers | Impulses that go to the CNS from the various body sites. |
What system controls involuntary unconscious mechanisms of the body? | Autonomic Nervous System |
What are the 2 branches of the Autonomic Nervous System? | Sympathetic and Parasympathetic |
Adrenergic | Refers to a drug stimulating a receptor for norepinephrine or epinephrine. |
Muscarinic Receptors | Stimulates AcH receptors at the Parasympathetic sites. |
Nicotinic Receptors | Stimulates AcH receptors at other locations including the Parasympathetic sites. |
What is the 1st step in the sequence of the stimulation of Sympathetic (Adrenergic) receptors? | Receptor stimulation |
What is the 2nd step in the sequence of the stimulation of Sympathetic (Adrenergic) receptors? | Production of adenyl cyclase |
What is the 3rd step in the sequence of the stimulation of Sympathetic (Adrenergic) receptors? | ATP Converts to cyclic AMP |
What is the 4th step in the sequence of the stimulation of Sympathetic (Adrenergic) receptors? | Cyclic AMP produces bronchodilation |
COMT (Catechol O-methyltransferase) | Rapidly breaks down or inactivates drugs such as epinephrine. |
MAO (Monoamine Oxidase) | It does the same thing as COMT, but is found in the intestines. |
Cholinergenic | Refers to a drug causing stimulation of a receptor for acetylcholine. |
Sympatholytic | An agent blocking the effect of the sympathetic nervous system. |
Sympathomimetic | An agent causing stimulation of the sympathetic nervous system. |