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arrythmic drugs
nursing pharmacology
Question | Answer |
---|---|
Quinidine | Antiarrythmic,purpuric rash,sinaitis,every 6 to 8 hrs,can cause digoxin toxicity. |
Procainamide(Procan) | butterfly rash |
Lidocaine(IV or IM) | Hospital based drug.Not available by mouth.Treat ventricular arrythmia |
Mexitil,Tonocard | Community used preparation by mouth |
Tenormin | Cardiac selective beta blocker |
Esmolol | used for surgical arrythmia. |
Tambocor n Rhythmol | most proarrythmic drug |
blood over 2.7 nanograms | digoxin toxic |
Atenolol | Cardiac arrythmia |
Digoxin toxicity | Blurryvision,halos |
Digoxin vital sign | affects pulse |
Digoxin | 70 percent bioavailable, lower dose of patient w/ kidney disease, twice a weeek or 3 times a week. |
Actual Diurectics | Remover pottasium from body .If low in K+ , it might add K+. |
Digoxin | inhibit Na, K + pump of a cell. K+ get pushed out of cell. |
Positive inotropic effect | Sodium inside cell trap Ca, Ca inside smooth muscle causes smooth muscle contraction |
Normal K+ level | 3.5-5.5 Meq/ml |
Lasix vs digoxin | drug interraction#2 |
Aspirin vs Coumadin | drug interaction#1 |
Normal blood level of digoxin | 0.5-2Ng/ml |
Sign of digoxin toxicity | Nausea, Vomiting, diarrhea |
Contractility | Strength of heartbeat |
Arrhytmia | deviation freom normal rates of heartbeat. |
Betablockers | treat trachychardia arrhythmia |
CHF(congestive heart failure) | decrease in cardiac contractility, heart not beating fast as strong as once it did. Heart do it in strength. |
Primary signs of CHF | Tachychardia |
CHF | decreased exercise tolerance, SOB, edema, peripheral n pulmonary edema. |
Treatment goals of CHF | Reduce workloads of heart, lose strength, eliminate sodium from heart. |
Mild edema | HCTZ |
Severe edema | lasix(loop diuretics) |
Ace Inhibitors | no effect on increasing force of heartbeat, reduce salt n water, reduce vascular resisstance, reduce symptoms of CHF and prolong life ,decrease angitension, |
Digotoxicity | suffer bradychardia less than 60 beats per mts |
Betapace | treats ventricular n atrial arrhythmias. This drug is part of K+ channel blocker n betablocker |
Betablocker | treats trachychardia |
Cordarone or Amidarone | part of Na,Ca,K+ channel blocker plus betablocker. Treats most type of arrhythmia. relax vascular smooth muscle n reduces afterload. |
Cordarone (duration of action) | 2 and a half- 10 days.Bioavailability-35-65 percent.intial onset of action- 2 to 3 days. |
SE cordarone | Pulmonary toxicity |
Symptoms SE cordarone | appears as cough,bronchospasm,sneezing,livertoxicity,,increased liver enzymes, thyroid dysfunction can cause hyperthyroid which can trigger new arryhthmia,loss of visiondue to optic neuritis, microcrystal dedposits on cornea, sunsensitivity. |
Adenosine | treats AV node arrythmia |
Adenosine-given IV | Durat of action15 seconds,hospital used |
pottassiun | antiarryhthmic, 2:1, so low,heart rate n rhythm depend on K . 3.5 Normal K. |
Angina | Chest pain |
cLASSIC ANGINA | stress, plaque buildup in arteries,responds to rest n medication. |
Vasoplastic angina | is cornary artery spasm can occur at anytime including sleep. |
Unstable Angina | does not respond to rest n medication. Thought to be precursor for heart attack. |
Treatment Angina | increased o2 delivery to heart, nitrates group of drug. Nitrates are vasodilators. |
Most popular nitrate | Nitroglycerin |
Sublingual | under the tongue |
proper use of Nitroglycerin | 1 tablet under tongue,every 5 mts until chest pain oAfter3 doses n 5 mts, if there is chest pain,after 3 doses r reached n 5 mts, there is chestpain, seek medical attention. |
Nitroglycerin | goes under tongue, internal jugular vein, right atrium. |
Transdermal Patch | apply nitroglycerin for 24 hrs, take all that patch, put the patch on. |
SE nitroglycerin patch | headache (will go away) |
Isosorbide mononitrate | drug help to mange chest pain |
Calan n Cardizem | Ca2+ channel. Blockers block calcium from entering smooth mucle which causes smooth muscle relaxation.BP,HEARTRATE,ARRYHTHMIA. |
Ca outside cell | relax |
Ca inside cell | contract (digoxin) |
IMDUR,ISMO,ISORDIL | HAS TO BE GIVEN 4 TIMES A DAY. |
NITROGLYCERIN | NOT TO BE GIVEN AS SWALLOW PREPARATION.UNDEGOES PASS EFFECTWHERE LIVER DESTROYS N DOESN'T GET IT TO THE BODY. |
NITROGLYCERIN | APPLY PATCH IN MORNING N REMOVE AT THE BED TIME. |