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Nitroglycerin
Nitrate
Question | Answer |
---|---|
Give three examples of Anti-anginals drugs? | Nitrate, Calcium Channel Blocker, Beta-Blockers |
Give examples of Anti-HTN drugs? | Nitrate, Calcium Channel Blocker, Beta-Blockers, Apresoline (Vasodilator), Minipress (Alpha-Blocker), Coreg (AlphaÎ’ Blocker), Cozaar (Angiotensin II receptor antagonists), Capoten (Ace inhibitor) |
Give examples SNS agonists drugs? | Intropin (Dopamine HCL), Dobtrex (Dobutamine HCL) |
Give examples of Anti-arrythmic drugs? | Xylocaine (Lidocaine HCL), Pronestyl (Procainamide HCL), Cordarone (Amiodorone HCL) |
Give examples of Anti-lipemic drugs? | Questran (Cholestyramine Resin), Mevacor (Lovastatin) |
Give examples of Blood Agents drugs? | Plavix Clopidrogrel Bisulfate), Trental (Pentoxifylline) |
Examples of Nitrates drugs? | Nitroglycerine, Imdur (Isosorbide Mononitrate) |
Examples of Beta-Blocker drugs? | Lopressor (Metropolol Tartrate), Inderal (propranolol HCL) |
Examples of Calcium- Channel Blocker drugs? | Procardia (Nifedipine), Cardizem (Diltiazem) |
What are Vasodilator drugs? | Apresoline (Hydralazine HCL) **Non-nitrate |
What are Ace-Inhibitor drugs? | Capoten (Captopril) |
What are Alpha Blocker drugs? | Minipress (Prazosin HCL) |
What are combo AlphaÎ’ Blocker drugs? | Coreg (Carvedilol) |
What are Angiotensin II receptor antagonists drugs? | Cozaar (Losartan Potassium) |
What drug is the number one choice for acute Angina Pectoris? | Nitroglycerine |
Nitroglycerine drug class? | Anti-anginal, Nitrate |
What happens when Nitroglycerine is adminstered? | Nitroglycerine decrease myocardial oxygen consumption, which decrease ischemia and relieved pain. |
What is the therapeutic action of Nitroglycerine? | NItroglycerine, relaxes vascular smooth muscle with a resultant decrease in venous return and decrease in arterial BP, which reduces left ventricular workload and decrease myocardial oxygen consumption. |
What does it mean Nitroglycerine vasodilator x 3? | Nitroglycerine dilates coronary arteries and peripheral arteries, and dilates veins. |
How does Nitroglycerine decrease the preload? | Nitroglycerine dilates the veins, causing pooling of blood throughout the body, decreasing the blood return to the heart, and filling pressure (preload) reduced. |
Do would you give NItroglycerine to Hypovolemic patient? | No, because hypovolemic patient doesn't have enough circulating blood volume, decrease filling pressure can cause significant decrease in CO and BP. |
Nitroglycerine sublingual: | Acute angina |
Nitroglycerine patch, transdermal, topical, sublingual: | Prophylaxis of Angina |
Nitroglycerine IV: | For hospitalized patient with recurring s/sx of ischemia or after revascularization procedure. |
Nitroglycerine other uses: | Treatment of Raynaud's disease (topical) |
NItroglycerine side effects? | CNS: Hypotension (major, ask pt. to sit down to avoid fall), HA, flushing, dizziness, DERM: Rash (from ointment), CV: Compensatory tachycardia (severe decrease in BP, may lead to increase in HR). |
Nitroglycerine contraindications: | Hypotension/Hypovolemia (=<90 systolic), Kidney and Liver problems, ICP, not for HTN, low PCWP, pericarditis, tamponade, and don't give to patient who took Viagra (hypotension) |
Patient teaching for Nitroglycerine: | 1) Keep meds in dark container. 2) Carry supply at all times. 3) Fresh tablets should cause burning sensation under tongue. 4) Purchase new supply every 4-6 months. 5) Take Nitroglycerine prophylactically to avoid pain: before any activity. |
Patient teaching for Nitroglycerine cont: | 6) Take Nitroglycerine when feel pain, and stop activity. 7) Take one pill, call 911, take second pill if still feel pain after 3-5 min, take third pill (max, if w/in an hour pain is not relieved, maybe MI. |
True or False? It's ok to give Nitroglycerine to someone who took Viagra. | No, Viagra can decrease of BP result in hypotension, and Nitroglycerine (vasodilator) major side effect hypotension. |