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Pharm. Antibiotics

Antibiotics in Pharmacology

QuestionAnswer
Antibiotics drugs that have the capability to kill microorganisms that invade the human body
Classification of antibiotics narrow spectrum (effective against a small number of microorganisms) and broad spectrum (effective against a large number of microorganisms)
Classification by MOA bacteriostatic (agents inhibit bacterial growth) and bactericidal (agents cause death and paralysis of microbes)
Most common adverse reaction allergic reaction (itch, rash, hive, and possibly anaphylaxis)
Advise clients to: a) finish all the medication b) take medications at evenly spaced intervals c) take missed dose as soon as remembered, but not at the same time as the next one
Cephalosporins chemical modification of penicillin, effective against rapidly growing bacteria
Cephalosporing MOA a) inhibit cell wall synthesis, b) and cell division and growth
First generation cephalosporins (mainly start with “cef” “ceph”) Cefazolin (Ancef; Kefzol), Cephalexin (Keflex), Cefadroxil (Duricef)
First generation cephalosporins USE surgical prophylaxis and preferred for most gram-positive organism infections
Second generation cephalosporins USE wider range of antimicrobial effect than first generation; TREATS gram-negative and anaerobic bacteria
Created by: csatlose
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