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HCE 240 patho
key terms chapt one
term | definition |
---|---|
Anaerobic | metabolism and function without oxygen |
Apoptosis | normal programmed cell death in tissues |
Autopsy | an examination of part or all of a body, including organs, after death (postmortem) to determine the cause of illness and death |
Biopsy | the removal of a small piece of living tissue for microscopic examination to determine a diagnosis |
Endogenous | originating from within the body |
Exogenous | originating from outside the body |
Gangrene | necrotic tissue infected by bacteria |
Homeostasis | a relatively stable or constant environment in the body, including blood pressure, temperature, and pH, maintained by the various control mechanisms |
Hypoxia | a decreased or insufficient level of oxygen in the tissues |
Iatrogenic | caused by a treatment, procedure, or error |
Idiopathic | no known cause |
Inflammation | the response to tissue damage, indicated by redness, swelling, warmth, and pain |
Ischemia | decreased blood supply to an organ or tissue |
Lysis | destruction of a cell |
Microorganism | very small living organism, not visible to the naked eye, usually single-celled |
Microscopic | visible only when magnified by lenses in a microscope |
Morphologic | the physical size, form, structure, and shape of cells or organs |
Probability | the likelihood or chance of occurrence |
atrophy | degeneration and wasting of tissue, organs, or muscle due to decrease in cell size |
hypertrophy | increased size of an organ or muscle due to increased size of individual cells |
hyperplasia | an abnormal increase in the number of cells resulting in an increased tissue mass |
metaplasia | replacement of one mature cell type by another mature cell type |
dysplasia | disorganized cells that vary in size and shape with large nuclei |
anaplasia | undifferentiated primitive cells of variable size and shape, associated with cancer |
neoplasm | abnormal growth of new cells, benign or malignant |
etiology | cause or origin of a disease or abnormality |
pathogenesis | the early stages in the development of a disease |
Latent | present but hidden and inactive |
Incubation period | the time between the initial exposure to the infectious agent and the appearance of the first signs of infection |
Prodromal | the initial period in the development of disease before acute symptoms occur |
Lesion | an abnormality in the structure of a tissue or organ |
Syndrome | a group of signs and symptoms characteristic of a specific disorder |
Exacerbation | an acute episode or increased severity of manifestations |
precipitating factor | condition that triggers an acute episode |
remission | manifestations of a disease subside |
complications | secondary/additional problems that arise after original disease begins |
sequelae | unwanted outcomes of primary condition |
Prognosis | the probable outcome of a disease |
Morbidity | the rate at which a disease occurs; the proportion of a group affected by a disease |
Mortality | the number of deaths in a group for a specific disease |
Epidemic | a disease occurring in higher numbers than usual in a certain population within a given time period |
epidemiology | science of tracking the pattern or occurrence of disease |
Occurrence | the incidence and prevalence of disease |
Incidence | the number of new cases of a disease in a certain population within a time period |
Communicable disease | a disease that can be transmitted from an infected person, directly or indirectly, to other susceptible hosts |
Necrosis | death or destruction of tissue |
liquefaction necrosis | process which dead cells liquefy under influence of certain enzymes (bacterial infections) |
coagulative necrosis | cell proteins altered or denatured (MI) |
fat necrosis | fatty tissue broken into fatty acids |
caseous necrosis | form of coagulation, thick, yellowish, "cheesy" substance forms. (TB) |
infarction | an area of dead tissue caused by lack of blood supply |
somatic death | death of the body |
brain death | lack of response to stimuli, EEG changes, and decreased perfusion in the brain |
–Congenital diseases | diseases occurring at birth |
–Remission | period when symptoms & signs of disease abates |
–Exacerbation | period when symptoms & signs increase |
–Endemic disease | disease native to local area |