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Pharm Ch. 13

CNS Depressans & Muscle Relaxants

QuestionAnswer
What are barbiturates? a class of drugs that are chemical derivative of barbituric acid, they can induce sedation and sleep
What are benzodiazepines? a chemical category of drugs most frequenctly prescrived as sedative hypnotic and anxiolytic drugs
What is Gamma aminobutyric acid? an inhibitory neurotransmitter found in the brain
What is Hypnotics? drugs that wehn given at low to moderate dosages, calm or soothe the CNS without inducing sleep but when given at high dosages do cause sleep
What is NREM sleep? The largest portion of the sleep cycle. it has 4 stages and precedes REM sleep
What is REM sleep? one of the stages of the sleep cycle. some of the characteristics of REM sleep are rapid eye movment of the eyes, vivid dreams, and irregular breathing
What is REM interference? a drug induced reduction of REM sleep time
What is REM rebound? excessice REM sleep following discontinuation of a sleep altering drug
What are sedatives? drugs that have an inhibitory effects on the CNS to the degree that they reduce nervousness, excitability, and irritability without causing sleep
What are sedatives hypnotics? drugs that can act in the body either as sedatives or as hypnotics
What is sleep? a transiet, reversible, and periodic state of rest in which there is a decrease in physical activity and conciousness
What is sleep architecture? the structure of the various elements involved in the sleep cycle, including normal and abnormal patterns of sleep
What is therapeutic index? the ratio between the toxic and therapeutic concentrations of a drug, if the index is low, the difference between the therapeutic and toxic drug concentrations is small, and use of the drug is more hazardous
What is retoril? short acting benzodiazepine, most common hypnotic, induces sleep in 20-40 min,
What is ambien? short acting nonbenzodiazepene hypnotic, short half life
What is lioresal? oral and injectable dose form, treat muscular conditions
What is flexeril? centrally acting muscle relaxant, reduces spasms after injuries
What are the short acting barbiturates? pentobarbital sodium, and secobarbital
What are the intermediate acting barbituates? amorbarbital, aprobarbital, and butabarbital
A pt has been admitted to the emergency department because of an overdose of an oral benzodiazepine. he is very drowsy but still responsive. the nurse should prepare what for immediate intervention? Flumazenil
An older adult has been given a benzodiazepine for sleep induction, but the night nurse notes that the pt was awake most of the night, watching television and reading in bed, this type of reaction is? A paradoxical reaction
The nurse is preparing to administer a medication for sleep. which intervention applies to the administration of a nonbenzodiazepine, such as zolpidem? Because of rapid onset, they should be taken just before bedtime
The nurse should monitor the pt who is taking a muscle relaxant for which AE? CNS depression
A pt on a cardiac medical surg unit is complaining of having difficulty sleeping. which action should the nurse take first to address this problem? Provide an environment that is restful and reduce loud noises
Created by: alicia.rennaker
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