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Pharm Ch. 16
Antiparkinsonian Drugs-NOT ON TEST!
Question | Answer |
---|---|
What is akinesisa? | a reduction or absence of psychomotor activity that results in a masklike facial expression and impaired postural reflexes. Characteristics of parkinson's disease |
What is bradykinesia? | slowness of movement, symptom of parkinson's disease |
What is Chorea? | a condition characterized by involuntary, purposeless, rapid motions such as flexing and extending the fingers, raising and lowering the shoulders, and grimacing |
What is dyskinesia? | an impaired ability to execute voluntary movements |
What is dystonia? | impaired or distorted voluntary movement due to a disorder of muscle tone |
What is exogenous? | a term describing any substance produced outside of the body that may be taken into the body |
What is on off phenomenon? | a common experience of pt's taking medication for parkinson's disease in which they experience periods of greater symptomatic control alternation with periods of lesser control |
What is parkinson's disease? | a slowly progress, degenerative neurologic disorder characterized by resting tremor, pull rolling of the fingers, masklike facies, shuffling gait, forward flexion of the trunk, loss of postural reflexes, and muscle rigidity |
What is postural instability? | a decrease or change in motor and muscle movements that leads to unsteadiness and hesitation in movement and gait when the individual starts or stops walking |
What is presynaptic? | drugs that exert their antiparkinsonian effects before the nerve synapse |
What is rigidity? | resistance of the muscles to passive movement: leads to the cogwheel rigidity seen in parkinson's disease |
What is tremor? | in parkinson's shakiness of the extremities seen mostly at rest |
What is wearing off phenomenon? | a gradual worsening of parkinsonian symptoms as pt's medications begin to lose their effectiveness, despite maximal dosing with a variety of meds |
What are the neurotransmission related abnormalities in parkinson's? | progressive generation of dopamine producing neurons in the brain |
What are drug therapies for parkinson's? | dopamine agonists, MAOIs, anticholinergics, and COMT inhibiters |
Which should alert the nurse to a potential caution or contraindication regarding the use of a dopaminergic drug for treatment of mild parkinson's disease? | Angle closure glaucoma |
A pt is taking entacapone as part of the therapy for parkinson's disease. which intervention by the nurse is appropriate at this time? | Notify the pt that this drug causes discoloration of the urine |
During a pt teaching session about antoparkinsonian drugs, the nurse will include which statement? | Change positions slowly to prevent falling due to postural hypotension |
A pt will be takin selegiline, 10 mg daily, in addition to dopamine replacement therapy for parkinson's disease. the nurse will implement which precautions regarding selegiline? | Monitor for synocope or dizziness |
A pt with parkinson's disease will start taking entacapone along with the carbidopa levodopa therapy he has been taking for a few years. the nurse recognizes that the advantage of taking entacapone is that? | the entacapone can reduce on off effects |