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Human Physiology

Immune System

Immune SystemImmune SystemImmune System Cells
Non-specific (Innate) type 1 defense mechanism
Specific (acquired) type 2 defense mechanism
Antigen anything that initiates an immune response
tolerance immunological unresponsiveness to self-antigens
innate immunity physical, biochemical, mechanical barriers (ex: inflammatory response)
acquired immunity antibody-mediated or cell-mediated immunity. requires recognition of antigen and activcation of lypmphocytes
antibody-mediated immunity acquired immunity. production and secretion of antibodies from B lymphocytes with help of T lymphocytes. antibodies facilitate opsonization, neutralization, agglutination, other events
cell mediated immunity directed against altered self-cells (virally infected/malignant) by stimulating T cytotoxic cells to release perforin that inserts into target cell and causes demise. T lymphocyte signals required for this process
primary response first response to an antigen, weak
secondary response stronger than primary response, subsequent response to antigen, memory
memory recalling an antigen
diversity recognizing a variety of substances not yet encountered
specificity generate molecules that specifically interact with antigens
Created by: soliria
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