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Cardiovascular meds

HTN, HF

Drug nameClassificationActionIndications
Vasotec (enalapril) ACE inhibitor vasodilator --- decreases afterload HTN; CHF
Zestril (lisinopril) ACE inhibitor vasodilator --- decrease afterload HTN; CHF
"-pril" ACE inhibitor blocks conversion of angiotensin I to angiotensin II HTN, adjunctive therapy for CHF; protects against kidney failure in diabetes
"-sartan" Angiotensin II receptor blockers blocks vasoconstriction effect of renin-angiotensin system HTN - good alt. for those who develop cough with ACE inhibitors
"-sin" Alpha adrenergic blockers vasodilator to decrease BP HTN
"-lol" Beta-adrenergic blockers decrease contractility in the heart, renin release of kidneys, and sympathetic output from vasomotor center of brain; binds to B1(cardiac)adrenergic receptor sites that prevent release of catecholamine HTN
Loressor (metoprolol) Beta 1-blocker cardiovascular
Tenormin (atenolol) Beta 1-blocker cardiovascular
Coreg (carvedilol) Beta 1&2-blocker nonselective Beta 1&2
Norvasc (amlodipine) CCB block calcium access to cells causing a decrease in contractility, decrease arteriolar constriction, decrease PVR, decrease BP Causes peripheral edema and venous dilation HTN
Lasix (furosemide) Loop diuretic inhibit Na, Cl, and H2O reabsorption in the proximal p/o the loop of Henle --- decrease preload Edema assoc w/CHF, cirrhosis w/ascites, or renal dysfunction. Furosemide for HTN.
Diuril (chlorothiazide) Thiazide diuretic Increase urine output by inhibiting reabsorption of Na, Cl, and H2O in the distal p/o the ascending loop of Henle Edema assoc w/CHF, cirrhosis w/ascites, or renal dysfunction. HTN.
Aldactone (spironolactone) K-sparing diuretic promotes excretion of Na and H2O, but retains K on the distal renal tubule Used w/loop or thiazide diuretics in treating CHF and HTN. Diuretic induced hypokalemia.
Osmitrol (mannnitol) Osmotic diuretic increases osmotic pressure of glomerular filtrate, thus preventing reabsorption of H2O. Increases excretion of Na and Cl Heart failure, renal failure, HTN, pulmonary edema due to transient increase in BP
Osmoglyn (glycerin) Osmotic diutretic (blank)
Ismotic (isosorbide) Osmotic diuretic (blank)
Catapres (clonidine) Central Alpha2 agonist decrease release of adrenergic hormones from the brain, resulting in a decrease in PVR and BP HTN
Lanoxin (digoxin) Antiarrhythmic Inhibits Na-K ATPase, resulting in an increase in cardiac contraction; decreases heart rate CHF; atrial fib and/or flutter; paroxysmal atrial contractions
Natrecor (nestritide) Vasodilator relaxes vascular smooth muscle; peripheral vasodilator; promotes diuresis Acutely CHF
Dobutrex (dobutamine) Inotropic; adrenergic Stimulate B1-adrenergic receptors (myocardial) to increase contractility but w/ relatively minor effect on HR Short-term mgt of heart failure due to decreased contractility
Nitroglycerin Antianginal; nitrate relax vascular smooth muscle system. decrease myocardial demand for O2, decrease left ventricular preload by dilating veins, thus decreasing afterload Angina pectoris
(blank) ACE inhibitor vasodilator - decrease afterload (blank)
(blank) Diuretics decrease fluid - decrease preload (blank)
(blank) Digitalis increase contractility (blank)
(blank) Nitrates vasodilator - decrease afterload (blank)
Dobutamine or Primacor (blank) improve contractility = improved CO & systemic perfusion (blank)
Created by: deliasgone
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