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Cardiovascular meds
HTN, HF
Drug name | Classification | Action | Indications |
---|---|---|---|
Vasotec (enalapril) | ACE inhibitor | vasodilator --- decreases afterload | HTN; CHF |
Zestril (lisinopril) | ACE inhibitor | vasodilator --- decrease afterload | HTN; CHF |
"-pril" | ACE inhibitor | blocks conversion of angiotensin I to angiotensin II | HTN, adjunctive therapy for CHF; protects against kidney failure in diabetes |
"-sartan" | Angiotensin II receptor blockers | blocks vasoconstriction effect of renin-angiotensin system | HTN - good alt. for those who develop cough with ACE inhibitors |
"-sin" | Alpha adrenergic blockers | vasodilator to decrease BP | HTN |
"-lol" | Beta-adrenergic blockers | decrease contractility in the heart, renin release of kidneys, and sympathetic output from vasomotor center of brain; binds to B1(cardiac)adrenergic receptor sites that prevent release of catecholamine | HTN |
Loressor (metoprolol) | Beta 1-blocker | cardiovascular | |
Tenormin (atenolol) | Beta 1-blocker | cardiovascular | |
Coreg (carvedilol) | Beta 1&2-blocker | nonselective Beta 1&2 | |
Norvasc (amlodipine) | CCB | block calcium access to cells causing a decrease in contractility, decrease arteriolar constriction, decrease PVR, decrease BP Causes peripheral edema and venous dilation | HTN |
Lasix (furosemide) | Loop diuretic | inhibit Na, Cl, and H2O reabsorption in the proximal p/o the loop of Henle --- decrease preload | Edema assoc w/CHF, cirrhosis w/ascites, or renal dysfunction. Furosemide for HTN. |
Diuril (chlorothiazide) | Thiazide diuretic | Increase urine output by inhibiting reabsorption of Na, Cl, and H2O in the distal p/o the ascending loop of Henle | Edema assoc w/CHF, cirrhosis w/ascites, or renal dysfunction. HTN. |
Aldactone (spironolactone) | K-sparing diuretic | promotes excretion of Na and H2O, but retains K on the distal renal tubule | Used w/loop or thiazide diuretics in treating CHF and HTN. Diuretic induced hypokalemia. |
Osmitrol (mannnitol) | Osmotic diuretic | increases osmotic pressure of glomerular filtrate, thus preventing reabsorption of H2O. Increases excretion of Na and Cl | Heart failure, renal failure, HTN, pulmonary edema due to transient increase in BP |
Osmoglyn (glycerin) | Osmotic diutretic | (blank) | |
Ismotic (isosorbide) | Osmotic diuretic | (blank) | |
Catapres (clonidine) | Central Alpha2 agonist | decrease release of adrenergic hormones from the brain, resulting in a decrease in PVR and BP | HTN |
Lanoxin (digoxin) | Antiarrhythmic | Inhibits Na-K ATPase, resulting in an increase in cardiac contraction; decreases heart rate | CHF; atrial fib and/or flutter; paroxysmal atrial contractions |
Natrecor (nestritide) | Vasodilator | relaxes vascular smooth muscle; peripheral vasodilator; promotes diuresis | Acutely CHF |
Dobutrex (dobutamine) | Inotropic; adrenergic | Stimulate B1-adrenergic receptors (myocardial) to increase contractility but w/ relatively minor effect on HR | Short-term mgt of heart failure due to decreased contractility |
Nitroglycerin | Antianginal; nitrate | relax vascular smooth muscle system. decrease myocardial demand for O2, decrease left ventricular preload by dilating veins, thus decreasing afterload | Angina pectoris |
(blank) | ACE inhibitor | vasodilator - decrease afterload | (blank) |
(blank) | Diuretics | decrease fluid - decrease preload | (blank) |
(blank) | Digitalis | increase contractility | (blank) |
(blank) | Nitrates | vasodilator - decrease afterload | (blank) |
Dobutamine or Primacor | (blank) | improve contractility = improved CO & systemic perfusion | (blank) |