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Unit 5 Cholesterol
LCC NURS 200 unit 5 Cholesterol Drugs
Question | Answer |
---|---|
Antiplatelet Drugs Prototype | Asprin |
Antiplatelet Drugs MOA | Block receptor sites on platelet membrane. |
Antiplatelet Drug Indications | Patients at risk for thromboembolic events (stroke, MI) |
Antiplatelet Drug Adverse Effects | Bleeding, GI distress, headache, dizziness, weakness. |
Anticoagulant Prototype | Heparin, enoxaparin (Lovenox), dalteparin (Fragmin), warfarin (Coumadin) |
Anticoagulants Indications | Prevents clots from forming/existing clots from growing in patients with thrombo-embolic event risk factors. |
Anticoagulants Adverse Effects | Bleeding, Thrombocytopenia, nausea, vomiting, abdominal cramps. |
Anticoagulants Contraindications/Cautions | Any condition that oculd be worsened by increased bleeding tendency. |
Anticoagulants Interaction | Warfarin has MANY, Nitroglycerine decreases effect of Heparin. |
Heparin Nursing Implications | Monitor effects of heparin by activated partial thromboplastin times (APTT or PTT), parenteral only, short half-life, |
Heparin antidote prototype | protamine sulfate |
Low-molecular weight heparins nursing implications | Somewhat safer and more predictable response, don’t require frequent lab monitoring, given subQ – not oral or IV. |
Warfarin (Coumadin) Nursing Implications | given orally only, several days to achieve therapeutic levels, monitored by prothrombine time (PT) and INR. |
Warfarin (Coumadin) antidote prototype | Vitamin K |
Thrombolytic Agent Prototype | streptokinase (Streptase, Kabikinase) |
Thrombolytic Agent MOA | convert plasminogen to plasmin wich breaks down fibrin threads in clots. |
Thrombolytic Indcations | Acute MI, Stroke and pulmonary embolus |
Thrombolytic Adverse Effects | Bleeding, Allergy/anaphylaxis |
Thrombolytic Contraindications/Cautions | Any condition where clotting is desirable (recent surgery, trauma, active bleeding). |
Thrombolytic Interactions | Other anticoagulants/antiplatelet meds must be closely monitored. |