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The COPDs

RESP: The COPDs (Chronic Bronchitis and Emphysema)

QuestionAnswer
presence of productive cough for at least 3 months, over at least 2 consecutive years chronic bronchitis
pathogenesis of chronic bronchitis? -atmospheric pollution -tobacco smoking -acute bronchitis
what is the target of chronic bronchitis? the entire tracheo-bronchial tree
what are the alterations of chronic bronchitis? -hyperemia -exudation -edema of mucous membranes
describe a typical CB patient an overweight male in his 50s with a history of tobacco smoking
what are the clinical manifestations of CB? -SOB on exertion -productive cough -edema -chills -insomnia -cor pulmonale
what is cor pulmonale? right sided heart failure
what is a significant complication in CB? bronchiectasis
increased volume of air spaces in the lungs, distal to bronchioles, with concomitant destruction of lung tissue emphysema
primary emphysema? genetic
secondary emphysema? infection and CB
alveolar emphysema location? panlobular, panacinar; primary
centrilobular location? centriacinar; secondary
clinical manifestations of emphysema? -thin, "wasted," barrel-chest -sudden onset: dyspnea, minimal cough (b/c no mucous) -pursed-lip breathing -wheezing respiration/tripod -expiration > inspiration
alveolar emphysema caused by? genetically controlled deficiency of alpha-1-antitrypsin (proteinase inhibitor)
pink puffer alveolar emphysema
air becomes trapped distally to obstructed bronchioles CB and centrilobular emphysema (secondary to CB)
blue bloater centrilobular emphysema
Created by: rebecky
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