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Intro to Infection
Question | Answer |
---|---|
what is flora? | organisms that routinely colonize appropriate surfaces without causing disease. Indigenous microflora are organisms which routinely colonize appropriate |
What is a pathogen? | Pathogen - an organism able to cause disease in a host |
Why would a microorganism cause symptomatic disease? | • Damaged host cells release substances used by pathogen in reproduction • Directly assists in spread of pathogen progeny • Coincidence |
What is an epidemic | Epidemic - a sudden increase in the number of cases of a disease, typically in a larger area |
What is an outbreak? | Outbreak - a sudden increase in the number of cases of a disease in a small, defined area |
What is an endemic? | Endemic - characteristic of a disease that exists continually at some level in an area |
What is a pandemic? | Pandemic - a disease outbreak affecting a high percentage of people over most of the globe |
What is an endogenous source? | Endogenous source - from within the body |
Exogenous source | Exogenous source - from outside the body |
What is nosocomial? | Nosocomial infection- an infection acquired while visiting a hospital/health care facility |
What is iatrogenic? | Iatrogenic infection- an infection introduced by a medical treatment |
What is an opportunistic pathogen? | Opportunistic pathogen - a normally non-pathogenic microorganism which causes disease typically in an immunocompromised patient |
What determines whether an encounter with a pathogen causes clinical disease? | age of the host, genetics of the host, genetics of the organism, route of exposure, microbial load |
What is acute course of infection? | short term and can treat with antimicrobials |
what is chronic/persistent course of infection? | you never get rid of the organism, and have persistent infection |
What is latent? | it goes away and comes back up |
persistent slow infection | following acute |
persistent slow infection | no acute |
features of a host-parasite relationship that work from the pathogens point of view | Pathogen benefits from a large and or transient population Pathogen may benefit from a basically unaffected host |