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U5: Female Repro
Female Reproductive System
Question | Answer |
---|---|
Organs of female reproductive system | ovaries, oviducts/uterine/fallopian tubes, uterus, vagina, vulva/pudendum |
Ovaries | female gonads; shape/size of almonds; located in pelvic cavity on lateral sides of uterus; smooth surface before produce/release eggs—scarred/pitted when they begin to produce w/ sexual maturation |
Broad ligament | support of ovary; sheet/fold of peritoneum that extends from lateral sides of uterus like tent flaps |
Ovarian ligament | support of ovary; distinct cord w/in broad ligament that extends from ovary to uterus |
Ovarian cortex | outer region of ovary; contains ovarian follicles |
Ovarian follicles | multicellular structures in ovarian cortex in which oocytes (immature egg cells) are located; each consists of several follicle cells and one oocyte |
Primordial follicles | in ovarian cortex; smallest, least mature of different categories of ovarian follicles; follicles from which all subsequent follicle stages are derived |
Ovarian cycle | activity that occurs in ovary in relation to menstrual cycle; beginning 6-12 primordial follicles begin to grow; usually all degenerate but one—primary follicle, which give rise to secondary follicle, which turns into a vesivular/mature/graafian follicle |
Follicle stimulating hormone (FSH) | from anterior pituitary gland; at beginning of each ovarian cycle, stimulates primordial follicles to grow |
Oogenesis | meiosis relative to egg cell production within follicles; produce ova; chromosome number reduced by half from 46 to 23 (dipload to haploid) |
Corona radiata | follicle cells that cluster most closely around oocyte |
Zona pellucida | barrier directly coating oocyte which sperm must ultimately penetrate to accomplish fertilization |
Ovulation | the rupture of a Graafian/mature/vesicular follicle and expulsion of its oocyte; occurs on about day 14 of ovarian cycle; stimulated by surge in secretion of luteinizing hormone (LH) from anterior pituitary gland |
Luteinizing hormone (LH) | hormone secreted from anterior pituitary gland; stimulates ovulation |
Corpus luteum | @ ovulation, most cells of ruptured Graafian follicle remain in ovary & are modified to form this structure; secretes estrogens, primarily progesterone; persists ~1st 2 mos pregnancy; if no fertilization, degenerates in about 2 wks forming corpus albicans |
Corpus albicans | tiny, white, scar-like spot on ovary from unfertilized and unimplanted corpus luteum |
Uterine tubes/fallopian tubes/oviducts | tubes receive ovulated oocytes from ovary; are usual site of fertilization; each begins near ovary, courses medially to empty into superior uterus |
Infundibulum | lateral, funnel-shaped portion of uterine tube near ovary; extending from this are the fimbriae |
Fimbriae | extend from margin of infundibulum; small, finger-like projections coated w/ cilia to draw ovulated egg cells into uterine tube. |
Ampulla of uterine tube | medial to infundibulum; most common site of fertilization |
Pelvic Inflammatory Disease (PID) | lack of continuity b/t ovaries & uterine tubes makes female vulnerable to this disease; widespread infection originates in vagina/uterus, spreads to uterine tubes/ovaries, & ultimately peritoneum of pelvic cavity; can cause scar tissue = infertility |
Ectopic pregnancy | involves implantation of embryo at any site other than uterus; if in uterine tube, can rupture and cause life threatening internal bleeding |
Salpingectomy | surgical removal of the uterine tube |
Salpingitis | inflammation of uterine tube |
Uterus/womb | located in pelvic cavity anterior to rectum, superior to bladder; if never pregnant, about size/shape of inverted pear; usually anteverted, but can become retroverted in older women; regions are body, fundus, cervix |
Fundus | region of uterus; rounded superior portion |
Cervix | region of uterus; neck-like, inferior, joined to vagina |
Body | region of uterus; largest & middle portion that lies between fundus and cervix; bulk of uterine cavity |
Cervical canal | passes through cervix to open at uterine cavity superiorly via internal os and opens at vagina inferiorly via external os; mucus |
Broad ligament, lateral cervical (cardinal) ligament, round ligaments | structures that support the uterus; most uterine support provided by muscles of pelvic floor (urogenital and pelvic diaphragm) |
Broad ligament | supports uterus; sheet-like, extends laterally from uterus like tent flaps |
Round ligament | supports uterus; cord-like; bind anterior uterus to back of the anterior wall of pelvic cavity |
Prolapse of uterus | if uterine supporting muscles—urogenital diaphragm, pelvic diaphragm—are torn during childbirth, this condition can occur; uterus falls to an abnormally low position, causing tip of cervix to protrude through vaginal orifice |
Rectouterine pouch | indentation located b/t rectum and uterus; most inferior part of abdominopelvic cavity, so pus from infections can drain to this pouch |
Uterine wall | three layers—permetrium, myometrium, endometrium |
Permetrium | in effect the visceral peritoneum of uterus |
Myometrium | thick, middle uterine layer made of smooth muscle tissue that provides for strong childbirth contractions |
Endometrium | innermost layer of uterus; in effect uterine mucosa; consists of lining of epithelium w/ sublayer of connective tissue called lamina propria; embryo burrows into this layer upon fertilization; two specific sublayers—stratum functionalis, stratum basilis |
Stratum functionalis | sublayer of endometrium; undergoes cyclic thickenings and thinnings in response to varied concentrations of ovarian hormones in blood; lost in menstruation about every 28 days |
Stratum basilis | sublayer of endometrium; forms new stratum functionalis after each menstruation |
Uterine cycle | refers to aspect of menstrual cycle that pertains to uterus; series of thickening, thinning phases of endometrium each month in response to altering blood levels |
Vagina | tube that extends inferiorly from cervix of uterus; lies anterior to rectum, posterior to urethra; "birth canal"; mucosa of stratified squamous epithelium for abrasion protection and underlying lamina propria; acidic pH due to beneficial resident bacteria |
Vaginal orifice | vagina’s external opening |
Hymen | near vaginal orifice, mucosa elaborates to form partial partition; membrane may be ruptured during exercise, insertion of tampon, or sexual intercourse |
Fornix of the vagina | indentation where superior part of vagina encircles tip of uterine cervix |
External genitalia/vulva/pudendum | structures include mons pubis, labia majora, labia minora, vestibule features |
Mons pubis | fatty, rounded pad overlying pubic symphasis; will grow hair at puberty |
Labia majora | extend posteriorly from mons pubis; two hair covered folds of skin; enclose labia minora |
Labia minora | two hairless folds of skin enclosed by labia majora; enclose vestibule |
Vestbule | area between labia minora; house external urethral orifice and vaginal orifice |
Greater vestibular (Bartholin’s) glands | flanking vaginal orifice; paired, pea sized glands that provide lubricating mucus during sexual excitation |
Clitoris | located where two labia minora meet at anterior point of vestibule; composed mainly of erectile tissue; sensitive and swells w/ blood during stimulation |
Female Perineum | floor of pelvis; in exact center lies central tendon/perineal body |
Central tendon/perineal body | center of perineum; structure serves as point of insertion for most muscles that support the pelvic floor/uterus; can be torn by infant’s head during delivery |
Episiotomy | performed during delivery to in attempt to avoid tearing of central tendon/perineal body; vaginal orifice is widened by posterior cut from it into clinical perineum at time baby’s head appears at vestibule |
Mammary glands/breasts | only function in lactating females when produce milk to nourish an infant in response to hormonal stimulation; internally has 15-25 lobes separated by adipose tissue and suspensory ligaments of breasts |
Lactiferous ducts | largest ducts in nipple; milk passes from lobules through progressively larger ducts until it reaches these |
Fertilization | occurs when nucleus of sperm unites w/ nucleus of egg; sperm reaches oocyte; binds to zona pellucida, releases digestive enzymes, which eat away at zona pellucida until slit is made which sperm can squeeze through |
Cleavage | series of mitotic cell divisions in fertilized egg/zygote; first forming morula (solid ball of cells) and then forming blastocyst (hollow ball of cells) |
Blastocyst | hollow ball of cells formed in cleavage; very early aspect of embryonic development consisting of 2 grps—inner cell mass, trophoblast |
Inner cell mass | group of blastocyst; will form body of embryo |
Trophoblast | group of blastocyst; will form placenta |
Implantation | process by which blastocyst burrows into endometrium of uterus; about 6 days after fertilization; takes about a week to be completed |
Placenta | serves as respiratory, digestive, urinary systems for fetus; permeable, but blocks passage of most bacteria from mother to fetus; many viruses and drugs can pass through placenta from mother to fetus |
Placenta previa | condition in which embryo implants in inferior aspect of uterine wall; consequently placenta may cover internal os of cervical canal; associated w/bleeding during last 3 mos of pregnancy; bed rest prescribed; can interfere w/ fetal development |
Placental abruption | condition in which placenta is in normal position, but becomes partly separated from uterine wall prior to birth; also produces vaginal bleeding during pregnancy; can interfere w/ fetal development |
Puberty | period of life b/t ~ages 10-15 when reproductive organs grow to adult size & reproduction becomes possible; due to rising levels of estrogens/testosterones |
Menopause | occurs ages ~46-54; associated w/ decreased activity of ovaries; ovulation ceases, stop producing estrogen, causing repro organs/breasts to atrophy, bone mass declines, blood cholesterol levels slowly rise, increasing risk of cardiovascular disorders |
Ovarian cancer | cancer that arises from epithelial cells on surface of ovary |
Endometrial cancer | cancer that arises from epithelium of endometrium; unfortunately postmenopausal estrogen-replacement therapy increases risk of this cancer |
Cervical cancer | cancer that arises from epithelial cells that cover tip of cervix; pap smear is best detection method |
Breast cancer | cancer that arises from epithelium of ducts in lobules of breasts; occurs in ~1 / every 8 women; risk factors are family history, post-menopausal hormone replacement therapy; often spreads rapidly via metastasizing from breast through lymphatic vessels |
Fibroids | slow growing, benign tumors in wall of uterus |
Hysterectomy | surgical removal of uterus, most frequently done to remove fibroids |
Endometriosis | condition in which fragments of endometrial tissue are located at a site outside of uterus such as uterine tubes, ovaries, peritoneum of pelvic cavity; can be painful due to thickening/thinning of out of place endometrial tissue |
Tubal ligation | tying and/or cutting the uterine tubes as a form of birth control |