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disorders of reprodu
reproductive tract
Question | Answer |
---|---|
characteristics of endometriosis | tissue appears in various places in pelvic cavity: ovaries, fallopian tubes, bladder, intestine, rectum, pelvic wall |
spread of tissue is believed to be through | lymphatic cirulation, menstrual backflow to the fallopian tubes and pelvic cavity, congenital displacement of endometrial cells |
characteristics of endometriosis | tissue appears in various places in pelvic cavity: ovaries, fallopian tubes, bladder, intestine, rectum, pelvic wall |
spread of tissue is believed to be through | lymphatic cirulation, menstrual backflow to the fallopian tubes and pelvic cavity, congenital displacement of endometrial cells |
hig incidence in what type of pts? | caucasion women b/w age of 25 and 35, woemen in higher sociaoeconomic classes, women who postpone childbirth until later reproductiv years. women who have never experienced childbirth or lactated, family hx of endometriosis |
more characteristics of endometriosis | the ectopic tissue apparently responds to stimulation by estrogen and perhaps progesterone tissue blees when endometruim of the uterus does, fallopian tubew becom occluded, sterility usually occurs, endometrial tissue bleedsinto the peritoneal cavity. |
s/s of endometriosis, even though cause in unknown and client may be symptomatic: | BLEEDING INTO PERITONEAL CAVITY, MENSTRUAL IRRECTULARITIES,severe abdoinal pain, dyspareunia abnormal pain during intercourse, pain on defecation, rectal bleeding/pain, appear 5 to 7 days before meses and last 2 to 3 days |
what are some types of menstrual irregularities? | dysmenorrhea-severe with copious bleeding, menorrhagia-abnormallylong or heavy menstrual periods, metrorhagia-uterine bleeding other than that caused by menstruation, amenorrhea-absence of menstruation... |
how does abdominal pain mimmick other pathologies? | may be unilateral or bilateral, may radiate to the lower back, legs and groin |
dx and tx of endometriosus | symptoms, pelvic examination which reveals fixed tender areas, laparaoscopy with biopsy oflesions may confirm dx, |
TX of endometriosis | antiovulatory meds to inhibit ovulation and induce a state physiologically similary to pregnancy, thus suppressing menstruation, Danazol (Danocrine) |
what hormone is effective in treating endometriosis? | A synthetic androgen (male hormone): may be effective because it inactivates and atrophies normal and endometrial tissue. |
what contraceptive is used to treat mild to severe endometriosis? | oral contraceptive estrogen-progestin combo used to treat mild to severe endometriosis |
what hormone is effective in treating endometriosis? | A synthetic androgen (male hormone): may be effective because it inactivates and atrophies normal and endometrial tissue. |
what releasing hormone agonist results in medically induced menopause, interru0ption of further lesion development, and lasts for 6 months... | Gonadotropin |
what contraceptive is used to treat mild to severe endometriosis? | oral contraceptive estrogen-progestin combo used to treat mild to severe endometriosis |
prognosis | half of women with endometriosis are infertile, menopause stops the progression of endometriosis |
prognosis | half of women with endometriosis are infertile, menopause stops the progression of endometriosis |
why would symptoms improve from endometriosis? | endometriosis may eventually result in sterility, but may be influenced by hormonal changes from pregnancy resulting in improving symptoms |
why would symptoms improve from endometriosis? | endometriosis may eventually result in sterility, but may be influenced by hormonal changes from pregnancy resulting in improving symptoms |
characteristics of endometriosis | tissue appears in various places in pelvic cavity: ovaries, fallopian tubes, bladder, intestine, rectum, pelvic wall |
spread of tissue is believed to be through | lymphatic cirulation, menstrual backflow to the fallopian tubes and pelvic cavity, congenital displacement of endometrial cells |
hig incidence in what type of pts? | caucasion women b/w age of 25 and 35, woemen in higher sociaoeconomic classes, women who postpone childbirth until later reproductiv years. women who have never experienced childbirth or lactated, family hx of endometriosis |
more characteristics of endometriosis | the ectopic tissue apparently responds to stimulation by estrogen and perhaps progesterone tissue blees when endometruim of the uterus does, fallopian tubew becom occluded, sterility usually occurs, endometrial tissue bleedsinto the peritoneal cavity. |
s/s of endometriosis, even though cause in unknown and client may be symptomatic: | BLEEDING INTO PERITONEAL CAVITY, MENSTRUAL IRRECTULARITIES,severe abdoinal pain, dyspareunia abnormal pain during intercourse, pain on defecation, rectal bleeding/pain, appear 5 to 7 days before meses and last 2 to 3 days |
what are some types of menstrual irregularities? | dysmenorrhea-severe with copious bleeding, menorrhagia-abnormallylong or heavy menstrual periods, metrorhagia-uterine bleeding other than that caused by menstruation, amenorrhea-absence of menstruation... |
how does abdominal pain mimmick other pathologies? | may be unilateral or bilateral, may radiate to the lower back, legs and groin |
dx and tx of endometriosus | symptoms, pelvic examination which reveals fixed tender areas, laparaoscopy with biopsy oflesions may confirm dx, |
TX of endometriosis | antiovulatory meds to inhibit ovulation and induce a state physiologically similary to pregnancy, thus suppressing menstruation, Danazol (Danocrine) |
what hormone is effective in treating endometriosis? | A synthetic androgen (male hormone): may be effective because it inactivates and atrophies normal and endometrial tissue. |
what contraceptive is used to treat mild to severe endometriosis? | oral contraceptive estrogen-progestin combo used to treat mild to severe endometriosis |
what releasing hormone agonist results in medically induced menopause, interru0ption of further lesion development, and lasts for 6 months... | Gonadotropin |
prognosis | half of women with endometriosis are infertile, menopause stops the progression of endometriosis |
why would symptoms improve from endometriosis? | endometriosis may eventually result in sterility, but may be influenced by hormonal changes from pregnancy resulting in improving symptoms |
why might surgery be needed? | to remove cysts and ectopic tissue to free the adhesions cause by bleeding without destroying childbearing function |
laparoscopy is used to do what with endometriosis? | remove small areas of endometrial tissue, releive adhesions |
what drastic surgical tx may be needed? | Panhysterectomy- removal of uterus, both fallopian tubes, and ovaries, hysterectomy: removal of a uterus, salpingectomy-removal of tubes, and oophorectomy: removal of ovaries |
how is endometrial tissue spread? | lymphatic ciruclation, menstrual backflow to thefallopian tubes and pelvic cavity, congenital displacement of endometrial cells |
Estrogen oral uses include | tx of mod to severe vasomotor symptoms of menopause, female hypogonadism, ovariectomy, primary ovarian failure, preventon of postmenopausl osteoporosis |
vaginal uses | atrophic vaginitis, during progestin cyclical therapy to decrease risk of endometrial carcinoma in pt with an intact uterus, |
used for conjugated estradiol | advanced inoperable metastatic breast and prostatic carcinoma |
conjugated IM/IV | uterine bleeding resultijg from hormonal imbalanc |
action | promotes growth and development of female sex organs, maintenance of secondary sex characteristics in women, metabloic effects include reduced blood cholesterol, protein synthese, and sodium and water retention |
Estradiol(Estrace, Gynodiol) continued: | acetate-Femtrace, cypionate-gepgynogen, depo, etc), valerate-(clinagen LA, Delestrogen), topical emulsion (Estrasorb), estradiol topical gel (divigel), estradiol transdermal spray (EvaMist), vaginal tablet-(Vagifem), vaginal ring-(Femring, Estring) |
Estrogens, conjugated: | Equine: premarin, synthetic A: Cenestin, synthetic, B: Enjuvia, Estropipate (Ogen, Ortho-Est, piperazine estrone sulfate) |
Contraindications | thromboembolic disease (dvt, PE, Mi, stroke) undx vaginal bleeding, liver dysfunction, pregnancy, lactation |
s/e | h/a, dizziness, thromboembolism, edema, htn, intolerance to contact lenses, worsenign of myopia or astigmatism, nausea, wieght changes, oily skin, gynecomastia, breakthrough bleeding, dysmenorrheal, amenorrhea, testicular atrophy |
drug interaactions | warfarin, oral hypoclycemic agents/insulins, barbiturates or rifampin, smoking, |
advantages of progestin over progesterone: | greater potency, longer duration, an effective oral or sublingual dosage form |
use: | decrease enodmetrial hyperplasia in postmenopausal woemn receiving concurrent estrogen (0.625 mg/day conjugated estrogens), pickwickian syndrom, sleep apnea, hypersomnolence, |
Action | secretory changes in ednometrium, increase basal body temperature, histologic changes invaginal epithelium, relaxation of uterine smooth muscle, mammary alveolar tissue growth, pituitary inhibit, w/dra bleeding in presence of estrogen |
contraindication | hypersensitifity, pregnancy, misssed abortion, thromboembolic disease, cerebrovascular disease, severe liver disease, breast or genital cancer, porhhyria, |
s/e | depression, retinal thrombosis, PE, trhomboembolism, drug induced hepatitis, gingival bleeding, cervical erosions, chloasma, melasma, rashes, edema, bone loss, anaphylaxis |
what is the hormone for milk production | prolactin |
let down reflex in the breast is achieved under the influence of what hormone | oxytocin |
where is the immature sperm stored? | epididymis |
what protects the urethra and vagina | labia minora |
muscle layer of the uterus | myometrium |