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Female Repro Path
Bakhtar-Female Reproductive Pathology
Question | Answer |
---|---|
types of Paget's Disease | intraepithelial adenocarcinoma bone: xs bone resorption as result of inflammatory response breast: malignant condition with skin changes involving nipple extramammary: involves primarily epidermis but occasionally extends into underlying epidermi |
endometriosis | can occur anywhere in the body deposition of 2 outta 3: 1)endometrial glands 2)endometrial stroma 3)hemosiderin major cause of infertility and pelvic pain origin: regurgitation thru FT, dissem. thru veins/lymphatics, metaplasia from coelomic e |
low grade squamous intraepithelial lesions LGIL, LGSIL | CIN I-moderate dysplasia |
high grade squamous intraepithelial lesions | CIN II-moderate dysplasia CIN III-severe dysplasia |
tamoxifen | used as anti-estrogen therapy for hormone-receptor positive breast cancer in pre-menopausal women |
salpingitis | infxn and inflamm of FT 2 types: 1)acute 2)chronic=change in architecture TB play big role in salpingitis worldwide; PID in U.S. |
salpingitis isthmica nosdosum | diverticulosis of FT: thickening of tunica musclaris of isthmic portion leads to complete obliteration of tubal lumen usually bilateral |
Stein-Leventhal syndrome | polycystic ovarian syndrome follicular cysts, anovulation, obesity, hirsutism |
benign germ cell tumor | mature teratoma ectodermally derived frequently skin, respiratory, conjunctiva epithelium any component of teratoma can develop a "mature malignancy" |
malignant germ cell tumors | dysgerminoma embryonal immature teratoma yolk sac choriocarcinoma |
dysgerminoma | malignant germ cell tumor undifferentiated ovarian counterpart of seminoma large vesicles with clear cytoplasm prominent lymphoid component |
embroynal tumor | malignant germ cell tumor primitive |
immature teratoma | malignant germ cell tumor somatic: resembles differentiation seen in fetus or embryo |
yolk sac tumor | malignant germ cell tumor extraembryonic rich in AFP Schiller Duval Body |
choriocarcinoma | malignant germ cell tumor placental or ovarian origin cytotrophoblasts and syncytiotrophoblasts present |
surface epithelial tumors | 1)serous 2)mucinous 3)pseudomyxoma peritonei |
tumor metastasis to ovaries | most common origin from gyn system 2nd common origin from digestive tract |
Krukenburg tumor | malignancy in ovaries that metastasized from stomach cancer found 80% in both ovaries |