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Test 2 NC1

NCI Hodge Reproduction Test 2

QuestionAnswer
Menstruation: 3 stages Proliferative phase/secretory phase/ luteal phase
Proliferative phase after menstruation. Period is Day 0 - 5, proliferative is about 7-14. Inc. FSH, Inc. estrogen, endometrial thickening.
FSH is the precursor hormone to ________ estrogen.
What is the strongest form of estrogen? Estradiol.
What is the pregnancy hormone? Progesterone
How is progesterone produced? By the corpeus luteum.
What happens to the corpeus luteum if the egg is not fertilized? It dies, stops producing progesterone and disintegrates.
What does progesterone do? Prepares the endometrial lining for implantation of the fertilized egg. Prepares breast for milk production.
If no fertilization occurs, what happens to the endometrium? It becomes hemorrhagic and is shed.
When is the Secretory Phase? day 14-28. Increase of LH, precursor to progesterone, causes ovulation and creation of corpus luteum.
Luteal phase Overlaps the secretory phase.
Normal length of cycle 21-40 days, usually 28
FSH stimulates the ________________ to release the _______________ estrogen/ ova
A reduction in circulating estrogen along with an increase in androgens in postmenopausal women is associated with breast and genital atrophy, reduction in bone mass, and increased rate of atherosclerosis
Abortions are classified as spontaneous (those occurring naturally) or induced (those occurring as a result of mechanical or medical intervention)
Although the etiology of breast cancer not completely understood, of factors are thought to relate to breast CA including a family history,environmental factors, genetics,early menarche,late menopause,age 60+. However, most women who develop breast cancer have no identifiable risk factors
An ectopic pregnancy is the implantation of the fertilized ovum anywhere outside the uterine cavity.Any blockage of the tube or reduction of tubal peristalsis that impedes or delays the zygote passing to the uterine cavity can result in tubal implantation.
Are antibiotics are used for acute and chronic bacterial prostatitis? Yes
Benign prostatic hyperplasia (BPH) is prostate gland enlargement due to increased epithelial cells and stromal tissue.
Benign prostatic hyperplasia (BPH) results from endocrine changes associated with the aging process
Benign prostatic hyperplasia (BPH) The compression of the urethra leads to clinical symptoms including decrease in caliber and force of the urinary stream, difficulty in initiating voiding, intermittency and dribbling
Breast cancer is the most common malignancy in American women except for skin cancer
Breast cancer is detected as a lump or mammographic abnormality in the breast
It occurs most often in the upper, outer quadrant of breast
Breast conservation surgery (lumpectomy) involves removal of entire tumor along with a margin of normal tissue.
Modified radical mastectomy includes removal of breast and axillary lymph nodes, but it preserves pectoralis major muscle.
Breast reconstructive surgery may be done simultaneously with mastectomy or some time afterward to achieve symmetry and to restore or preserve body image
BSE Breast self-examination is an option for women. Done by 25% of the population. Discover a large amount of cancers in this method
CERVICAL CANCER There is a strong relationship between sexual exposure of papillomavirus (HPV) and dysplasia
2 strains of HPV that are most problematic 16 and 18
Definitive diagnosis of breast cancer is made by histologic examination of biopsied tissue. Biopsy techniques include fine-needle aspiration (FNA) biopsy, stereotactic or handheld core biopsy, and open surgical biopsy.
Dysmenorrhea is abdominal cramping pain or discomfort associated with menstrual flow.
Elevated levels of prostate-specific antigen (PSA) indicate prostatic pathology, although not necessarily prostate cancer.
Endometriosis is the presence of normal endometrial tissue in sites outside endometrial cavity
Endometriosis Symptoms are secondary dysmenorrhea, infertility, pelvic pain, dyspareunia, and irregular bleeding.
Epididymitis is an acute, painful inflammatory process of the epididymis secondary to an infectious process, trauma, or urinary reflux down the vas deferens.
Epididymitis Antibiotic use is important for both partners if transmission was through sexual contact
Epididymitis Conservative treatment consists of bed rest with elevation of scrotum, use of ice packs, and analgesics
Estrogen is essential to development and maintenance of secondary sex characteristics, proliferative phase of menstrual cycle immediately after menstruation, and pregnancy uterine changes
Estrogen and progesterone are produced by the ovaries
Fibroadenoma is a common cause o benign breast lumps in young women. A possible cause may be increased estrogen sensitivity in localized area of breast. Treatment includes surgical excision or cryoablation. Fibrocystic changes is a
Gynecomastia is a transient, noninflammatory enlargement of one or both breasts and is the most common benign breast problem in men.
Hormonal blood studies are essential for a fertility workup.
Hormonal therapy removes or blocks the source of estrogen, thus promoting tumor regression
If fertilization does not take place, menstruation occurs because of a decrease in estrogen production and progesterone. If fertilization occurs, high levels of estrogen and progesterone continue to be secreted due to continued activity of corpus luteum from stimulation by human chorionic gonadotropin (hCG)
HCG Human chorionic gonadatrophin
If palpable, breast cancer is usually hard, and may be irregularly shaped, poorly delineated, nonmobile, and nontender. Nipple discharge may also be present.
Androgens precursor of all estrogens
Bartolian cysts pea shaped lump. Can become inflamed and very large, may require incision and drainage.
LH causes the release of the__________ ova
Fundus - position before and during pregnancy. Before - deep and low. Around 20 weeks, behind the umbilicus. Post delivery, massage to stop bleeding.
HCG Human chorionic gonadatrophin
If palpable, breast cancer is usually hard, and may be irregularly shaped, poorly delineated, nonmobile, and nontender. Nipple discharge may also be present.
Tests useful in predicting risk of recurrence or metastatic breast disease include axillary lymph node status, tumor size, estrogen and progesterone receptor status, and cell proliferative indices. In women, follicle-stimulating hormone (FSH) is produced by anterior pituitary; stimulates growth and maturity of ovarian follicles
Infection and inflammation of vagina, cervix, and vulva commonly occur when natural defenses of the acid vaginal secretions (maintained by sufficient estrogen levels) and presence of Lactobacillus are disrupted
Infection and inflammation of vagina, cervix, and vulva Tx includes antibiotics and antifungal preparations
Infertility is the inability to achieve a pregnancy after at least 1 year of regular intercourse without contraception
Inflammatory breast cancer is the most malignant form of all breast cancers
Inflammatory breast cancer The skin of the breast looks red, feels warm, with a thickened appearance described as resembling an orange peel (peau d’orange)
Inflammatory breast cancer Metastases occur early and widely. Radiation, chemotherapy, and hormone therapy are more likely to be used for treatment than surgery
Invasive treatment of symptomatic BPH involves prostate resection or ablation
Lactational mastitis manifests as a localized area that is erythematous, painful, and tender to palpation
Leiomyomas (uterine fibroids) are benign smooth-muscle tumors that occur within the uterus
Leiomyomas (uterine fibroids) Symptoms may include abnormal uterine bleeding, and pain
Leiomyomas (uterine fibroids) Treatment depends on size of tumor and may include surgery
Lymphedema can occur due to surgical excision or radiation of lymph nodes. Symptoms are heaviness, pain, impaired motor function in the arm, and numbness and paresthesia of the fingers as a result of lymphedema
Mammography is used to visualize internal structures of the breast using x-rays. This procedure can detect tumors and cysts not felt by palpation
Mammoplasty In augmentation, an implant is placed in a surgically created pocket between the capsule of the breast and the pectoral fascia
Mastalgia (breast pain): is the most common breast-related benign complaint in women. It is described as diffuse breast tenderness or heaviness
Mastalgia (breast pain): Some relief may occur with caffeine and dietary fat reduction; hormonal therapy, taking vitamins, and gamma-linolenic acid (evening primrose oil); and wearing of support bra
Mastitis is a breast inflammatory condition that occurs most frequently in lactating women
Most common site of ectopic pregnancy the fallopian tubes
Menarche is the first episode of menstrual bleeding, indicating that a female has reached puberty. This usually occurs at 12 to 13 years of age
Menopause is the physiologic cessation of menses associated with declining ovarian function. It is usually considered complete after 1 year of amenorrhea
Menopause Treatment might include hormone replacement, drug therapy, and alternative therapies
Noninvasive breast cancers include ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS)
PID is often the result of untreated cervicitis, usually treated with antibiotics
Paget’s disease is a rare breast malignancy characterized by a persistent lesion of the nipple and areola with or without a palpable mass.Treatment is a simple or modified radical mastectomy
Tamoxifen drug used to stop all estrogen post cancer.
Pelvic inflammatory disease (PID) The main symptom is constant lower abdominal pain
Pelvic inflammatory disease (PID) Long-term complications include ectopic pregnancy, infertility, and chronic pelvic pain
Premenstrual syndrome (PMS) Physical symptoms include breast discomfort, abdominal bloating, sensation of weight gain, episodes of binge eating, and headache. Anxiety, depression, irritability, and mood swings are some of the emotional symptoms
Primary dysmenorrheal is caused by an excess of prostaglandin F2α (PGF2α) and/or an increased sensitivity to it
Prolactin assay is used for patient with amenorrhea
Prostate cancer is the most common cancer among men, excluding skin cancer
Prostate cancer The conservative approach to management is “watchful waiting.”
Reduction mammoplasty is performed by resecting wedges of tissue from upper and lower quadrants of breast. The primary roles of male reproductive system are production and transportation of sperm, deposition of sperm in female reproductive tract, and secretion of hormones
Screening guidelines for early detection of breast cancer are yearly mammograms starting at age 40, and clinical breast examinations every 3 years for women between ages 20 and 30 and every year for women beginning at age 40
Serum hormone test, hCG, is used to identify pregnancy.
Symptoms of prostate cancer are similar to those for BPH, including dysuria, hesitancy, dribbling, frequency, and urgency
The etiology of ovarian cancer is generally not known
The first sign of endometrial cancer is abnormal uterine bleeding
The hypothalamus, pituitary gland, and gonads secrete numerous hormones that regulate the processes of ovulation, spermatogenesis, fertilization, and formation and function of secondary sex characteristics
The major functions of ovaries are ovulation and secretion of hormones. These functions are accomplished during the menstrual cycle
The major gonadal hormone of men is testosterone, which is produced by the testes.
Testosterone is responsible for development and maintenance of secondary sex characteristics and spermatogenesis
The primary female reproductive organs are the ovaries
The primary male reproductive organs are the testes
The primary roles of female reproductive system are production of ova, secretion of hormones, and protection and facilitation of the development of the fetus in a pregnant female. Uterine prolapse is
Uterine prolapse symptoms are dyspareunia, dragging or heavy pelvic feeling, backache, and bowel or bladder problems if cystocele (bladder) or rectocele(rectum) or interocele (intestines) is also present
Uterine prolapsed therapy depends on degree of prolapse and can include strengthening exercises, and a pessary
ductal carcinoma in situ DCIS tends to be unilateral and most likely would progress to invasive breast cancer if left untreated
ectopic pregnancy Risk factors include a history of PID, prior ectopic pregnancy, (IUD), progestin-only birth control failure, and prior pelvic or tubal surgery
ectopic pregnancy Surgery is usually the treatment but can use chemo
Methotrexate chemo drug used to treat ectopic and leave tube functioning
ovarian cancer usually identified in later stages
ovarian cancer In the early stages, manifestations are vague and may consist of abdominal discomfort (gas, indigestion, pressure, bloating, cramps) and change in bowel habits
ovarian cancer diagnostic test may include CA 125
prostatitis It includes acute bacterial prostatitis, chronic bacterial prostatitis, chronic prostatitis/chronic pelvic pain syndrome, and asymptomatic inflammatory prostatitis
nocturia night urination
dysuria painful urination
hematuria blood in the urine
hematospermia blood in sperm
PSA prostate specific antigen
2 types of ejaculation problems premature and retrograde
BPH statistics 50% of men over 50, 80% over 80.
Created by: TCC2013
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