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1231 Final BP
Question | Answer |
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Special Teaching about expectorants: | pt should be aware that these drugs will make sputum more liquid, use a humidifier and drink at least 2qts of water daily. This will help get mucus out. Notify if cough is present w/high fever, or persistent HA or if cough returns! |
Decongestents along with HTN | Decongestants increase BP and HR |
Antitussives may cause | drug dependence. Some are Schedule 2 Controlled Substances. They should only be used a short time. |
Give oral doses of antihistamines with | meals or milk to limit GI s/e. |
Start the amount of dose of antihistamines as | low as tolerated and needed. With ELDERLY start low and stay low. |
Antihistamines have what kind of effect on the CNS | Sedative effect. and it is increased when other CNS depressants are used along with antihisamines. |
How are antibiotics chosen? | depends on the infectious organism (identified by cultures or smears) |
Important Patient teaching for Differin Gel | Wash face then apply a thin film of gel once daily to affected areas. An exacerbation of acne may initially be seen; therapeutic results usually seen in 8-12wk. |
Agents that are Bactericidal | kill bacteria |
Aderse reactions to anti-infectives? | Neuropathy (nerve damage), fixed drug eruptions (single spot that itches), N/V, epigastric distress, anemia, blood dyscrasias, rash, Erythema, urticaria, angina, edema, swelling of skin and mucous membranes, laryngeal edema and anaphylaxis |
What is the treatment for active TB | Rifampin and Isoniazid - 6mo - 1 year, most be compliant |
Penicillin Action | Broad spectrum, interferes with creation of cell wall. |
Penicillin is used to | treat infections. |
Adverse reactions of Penicillin | neuropathy, fixed drug eruptions, NV, epigastric distress, blood dyscrasias, rash, urticaria, edema, anaphylaxis. |
Drug interactions of Penicillin | bacteriostatic antibiotics, bacteriocidal antibiotics, birth control produces menstrual irregularities, and unplanned pregnancies |
Thiazide diuretics | Keeps the kidneys from reabsorbing Sodium, Potassium, and Chloride. First treatment for HTN. |
Treatment for HTN diabetics | ACE inhibitors |
Special teaching for pts on antibiotics and birth control medications | Use backup contraceptive, antibiotics lessens the affects. |
Use of ampicillin and oral contraceptives together has produced | menstrual irregularites and unplanned pregnancies. |
Cephalosporin and penicillin with allergies causes | nephrotoxicity >incidence in elderly or pt w/poor renal function. |
What are broad spectrum antibiotics? | Antiinfective drugs effective against a wide variety of organisms. |
Tetracycline special teaching | take on an empty stomach, avoid sunlight, DO NOT take w/milk, grayed teeth, black hairy tongue, avoid milk iron supplements and antacids. |
Teaching needed with all antibiotic medications | Take until prescription is over, add another form of contraceptive, antibiotics provide an overgrowth of yeast, could cause superinfection and bacterial changes in bowel |
Adverse reactions to Penicillin | hypersensitivity reactions, hematological reactions, transient neutropenia, leucopenia, thrombocytopenia, bleeding can occur with high dose extended-spectrum penicillins |
Cromolyn sodium helps treat asthma by | slowing down the destruction of sensitized mast cells |
Cromolyn and nedocromil sodium, a drug with actions similar to those of cromolyn, are used to manage | bronchial asthma in some pts. |
Penicillin, amoxicillin, cloxacillin | Common Penicillins |
How do you know if aminoglycosides are working | ▼BP, HR, WBC, when symptoms subside and pt starts feeling better. |
Zovirax (acyclovir) Purpose | For initial and recurrent mucosal and cutaneous HSV1, HSV2, and varicella-zoster infections in immunocompromised individuals. Severe acute and recurrent genital herpes in pts not immunocomprimised. Acute treatment of herpes zoster and chickenpox lesions. |
Zovirax (acyclovir) Dosage | Initial parenteral infusion followed by oral therapy. Dosage depends on condition, acuity, and severity. Dose is usually 800mg PO 5times daily for 7-10 days. |
Nystatin Action | Most commonly used polyene antibiotic with fungistatic or fungicidal activity. Drug may allow intracellular components to leak through fungal cell membrane by binding to sterols in cell membrane. |
Nystatin Uses | Used to treat intestinal, vaginal, and oral fungal infections caused by susceptible strains of Candida albicans and other Candida species. |
Nystatin Adverse Effects | Nausea, vomiting, diarrhea. |
What is a superinfection? | Viral infection in addition to the infection the pt is on medication for, yeast being the most common, diarrhea and other GI symptoms are common. |
When would you develop a superinfection? | Results when using broad spectrum antibiotics. |
Atineoplastic Adverse Reactions | Depend on the dose given. NV, Anorexia, and diarrhea are seen w/almost all products. Other common reactions include alopecia, and bone marrow depression. Renal tox, Hepatic tox, ototox, ocular effects, peri neurotox, and hypersensitivity are common. |
Antineoplastic agents are some of the most dangerous drugs given to pts. However, they may save the pts life, so the benefit outeighs the risk. You must always watch the | pt and look for changes that might be the onset of serious adverse reactions. |
What are common treatments for nausea associated with atineoplastic meds? | Antiemetics may be prescribed for nausea, special skin care may be needed and analgesics or narcotics may be required. |
Why get immunizations? | to Decrease chance of getting diseases |
What is PPD? | PPD: TB test, if PPD is positive you have been exposed to TB |
What are toxoids? | Part of the disease altered. |
artifically acquired passive immunity | the type of immunity you get from vaccines |
Muscle relaxants are used in treatment of | spasticity. |
Muscle relaxants Adverse Effects | nervousness, insomnia, weakness, speech disturbance, photosensitivity, urinary frequency or retention, nocturnal diuresis, erectile dysfunction, depression, seizures. |
Quinine is for | leg cramps. |
Dantrium treats | spasticitiy |
Colchicine Treats | gout. Antiinflammatory; effects specific for gout. |
Colchicine Adverse Effects | NV, diarrhea, abdominal pain |
NSAIDs treats | pain |
allopurinol prevents | gout |
Adverse reactions, side effects, and precautions to ASA | GI bleeding, ototoxicity, gums bleeding, check all products for aspirin, visual disturbances, edema |
Gout is | for of arthritis where uric acid accumulates in increased amounts in the blood and is often deposited in joints. |
Metotrexate is used for | varoius cancerous and psoriatic conditions. Decreases joint swelling and tenderness in 3-6 weeks. Has many contraindications, used for RA, malaria, abortion. |
anorectal preps: dibucaine (Nupercainal) | Pt should apply ointment morning and night after each bowel movement. For suppositories, one should be inserted after each bowel movement. |
anorectal preps: hydrocortisone acetate (anusol-HC) | contains hydrocortisone |
anorectal preps: zinc sulfate monohydrate (anusol, preparation H) | Suppository should be inserted in the morning and at bedtime for 3-6 days or until inflamation subsides; or cream may be applied to anal area and gently rubbed in 3-04 times daily for 3-6 days |
anorectal preps: hydrocortisone foam (Proctofoam-hc) | steroid used for antiinflammatory treatment of ulcerative proctitis and distal ulcerative colitis. Contains hydrocortisone. Pt would insert one applicatorful in rectum daily or twice daily for 2-3wks. Then every other day, decreasing gradually. |
Anorectal preparations include | emollients, foams, and gels for topical anesthesia or healing of the rectal area. They are used for symptomatic relief of discomfort of hemorrhoids. They may be used for short term or long term. |
Use the pain intensity scale for | adults. |
Use the wong-baker face scale for | children and pts with a language barrier. |
Flomax treats | symptoms of BPH by selective inhibition of alpha1A receptors |
Flomax Adverse Effects | postural hypotension, dizziness, somnolence, rhinitis, diarrhea, abnormal ejaculation. |
Flomax drug interactions | potentiates other alpha adrenergic blcoking agents |
Flomax Nursing Imps and pt teaching | take at the same time every day, approx 1/2 hour AFTER eating, may take 2-4wks before response is seen. |
Flomax is an alpha-adrenergic antagonist | a non-diuretic drug used to treat urinary problems |
Lopressor | anti HTN, anti-anginal, prevents MI |
Pyridium | treats UTI, orange urine |
Diuretics and hypertension | First choice for treatment |
Elderly pts are more susceptible to to the development of the adverse reactions associated with diuretics such as | postural hypotension, impaired mentation, hypokalemia (except with potassium sparing diuretics), and increased serum glucose levels. |
Lower doses of diuretics are advised in the | elderly population, with dosage increases based on the pts individual therapeutic response and/or the development of adverse reactions. |
Pts taking diuretics must be observed for symptoms of Potassium loss. This is often seen when the pt develops | muscle weakness and other symptoms of dehydration. Many pts require potassium replacement while taking diuretics and digitalis. |
Diuretics indirectly reduce blood pressure by | producing sodium and water loss and lowering the tone or rigidity of the arteries |
Zocor Side Effects | Abdominal cramps, GI problems |
Statin Medications | Hyperlipidema - lowers cholesterol |
Ativan | aka Lorazepam treats anxiety disorders |
Teaching when taking migraine meds | take with meals or milk, keep arms and legs warm, lay down in a dark room |
Elavil | antimigraine, tension HA |
Valium | aka Diazepam. Sedative, status epilepticus |
Imitrex | antimigraine |
Dilantin | treat tonic clonic and psychomotor seizure, increased ventricular force, dental care - massage gums to prevent hyperplasia. |
Aircept | used in alzheimers mild/moderate dementia |
What are some common Parkinson meds and what is the goal of treatment? | anticholinergic and dopaminergic are used to control parkinsons by changing the transmitters produced in the braine. Levedopa and Carbidopa, early signs of blephrospasms and muscle twitching. |
Elimite | pediculocyte, use again 7-10 days, use in 1-2 applications, don't use on pets and babies. report to school nurse. |
Nicotine patches special teaching | don't smoke, alternate application site |
Antipsoriatics | accelerates scaling in chronic psoriasis |
Miotic drugs | open-angle glaucoma, constricts pupils |
Mydriatic drugs | dilate pupils, contraindicated in glaucoma |
Treatment of calluses | salicylic acid |
Proparacaine | topical anesthetic used for cataract surgery |
Codeine | narcotic antitussive |
Mucomyst | (acetylcholine) antidote for acetaminophen overdose |
When to take pain meds? | First sign of pain. |
Timoptic | beta blocker that decreases intraocular pressure |
Accutane | treats severe acne, avoid sun and pregnancy |
Anticoagulants | prevent clots |
Thrombolytics | break down clots |
protamine sulfate | antidote for heparin |
vitamin k | antidote for coumadin |
PT | coumadin (norms 1.5-2.5) |
PTT | Heparin (norms 2.5-3x the control volume) |
Protonix | proton pump inhibitor for gastric and duodenal ulcers take 1 hour before meals |
Antispasmodics and anticholinergics | work antacids in continuing the therapeutic benefits of both (irritable bile syndrome) (dry up) |
Simethicone ACtion | Antiflatulents! defoaming action |
simethicone use | relief for excess gas (takes air out of stomache |
Simethicone adverse effects | typically causes diarrhea |
Disulfiram action | (antialcoholic) used only for the mgmt of alcoholism, discourage alcohol intake and force pt to be sober. |
Disulfiram Side effects | drowsiness, fatigue, HA, psychoses, optic neuritis, hepatic toxicity, metallic/garlic like taste, erectile dysfunction, |
Disulfiram: Notify dr of signs of | hepatoxicity, yellow eyes or skin, dark urine, light-gray colored stools or severe stomach pain |
Strokes and ASA | dose 1xday for men |
Foods that affect coagulation | green leafy veggies |
Heparin | short term IV use, prevention of clots |
Coumadin | most often used for long term use |
Corticosteroid therapy | used to control long term asthma |
Hormone replacement therapy | increased risk for cancer |
Progestin action | transform proliferate endometrium into secretory endometrium (causes early menopause) Necessary for the development of the placenta and inhibits the secretion of pituitary ganadotropins, preventing maturation of the ovarian follicle and ovulation. |
Progestin uses: | amenorrhea, endometriosis, functional uterine bleeding, contraception |
Progestin adverse effects: | breakthrough bleeding, spotting, changes in menstrual flow, amenorrhea, tender breast, edema, wt increase or decrease, acne, chloasma, melasma, depression |
Levothyroxin | used for hypothyroidism |
ACE inhibitors | interfere with renin-angiotensin-aldosterone-system, decrease BP. |
Ace Inhibitor drugs | catapril, benzapril, enalapril, quinapril, ramipril, lisinopril |
Ace inhibitors adverse effects | most common dry hacking cough, HA dizziness, tachycardia, palpations, 1st dose syncope |
Lanoxin (digoxin) | used for arrythmias. Monitor closely, check apical pulse if <60 hold meds. |
Nitroglycerin | keep in a dark bottle, out of sun |
What does a narrow margin for digoxin mean | .5 to 2 ngmg |
Paxil treats | depression, panic and eating disorders, obsessive compulsion, premenstrual dysphoria, ptsd, bipolar, alcohol dependence, premature ejac, diabetic neuropathy. |
Paxil adverse effects | GI complaints, HA, dizziness, somnolence, sexual dysfunction, tremors, less common: tender breast or enlargement, fever, palpations, wt gain or loss, rash, hieves, itching |
Lithium | an antimanic acts by altering sodium transport in nerve and muscle cells and inhibits the norepinephrine and dopamine release |
lithium adverse effects | metallic taste, dizziness, ha, confusion, recent memory loss, drying and thinning , wt loss or gain, edema of hands and ankles, reversible leukocytosis, cardiac dysrhythmias, nephrotox, toxicity |
Lithium special teaching | Monitor sodium levels carefully! encourage fluid intake. |
When a diuretic is discontinued it is recommended that the drug be | reduced gradually to avoid the development of serious edema. |
Thiazides work to prevent the reabsorption of | sodium and chloride through direct action on the end of the ascending loop and the beginning of the distal tubule of the loop of Henle. |
Thiazides block the sodium and chloride | reabsorption and slightly limit carbonic anhydrase. |
Thiazides have a long half-life that may lead to the loss of large amounts of | potassium. |
Thiazides also act directly to dilate the smooth muscles in the | arterioles, the smallest vessels in the areterial system. |
When the arterioles are made larger, the heart does not have to pump so hard to get blood into them. This helps keep | blood pressure lower. |
permethrin (Elimite, Nix, Acticin) is a | scabicide/pediculicide. Sprinkle lotion into dry hair and rub into scalp. |
Permethrin (Elimite) action | causes repolarization and paralysis in lice by disrupting sodium transport in normal nerve cells. DEATH TO PARASITES!!! |
proparacaine (Alcaine) is a | local opthalmic anesthetic. Use 1-2 drops immediately before tonometry, 2-3 minujtes before suture removal or removal of foreign body. |
codeine (Codeine Phosphate, Codeine Sulfate) is a | Narcotic Agonist Analgesic. Schedule 2 drug. |
Codeine indications | management of mild to moderate pain. Antitussive (in smaller doses). |
Codeine Actions | Binds to opiate receptors in the CNS. ALters the perception of and response to painful stimuli while producing generalized CNS depression. Decreases cough reflex and GI motility. |
Codeine Side Effects | confusion, sedation, hypotension, constipation, nausea, vomiting |
Codeine Nursing Imps include checking vital signs regularly and assess sedation if respiratory rate is <10/min. Assess bowel function regularly. Assess type, location and intensity of pain before and | 1 hour (peak) after administration. Prolonged use may lead to dependance and tolerance. |
Codeine overdose antidote | Narcan |
Morphine (Duramorph, MS Contin, MSIR) is a schedule | 2 drug that is a narcotic agonist analgesic. |
Morphine is the primary narcotic analgesic used for relief of | severe pain. Morphine is the narcotic analgesic against which all others are compared. |
Morphine produces | sedation and euphoria when pain is present. Traditionally used for preop sedation and post op analgesia. |
Morphine is more effective against | dull, continuous pain than sharp, spasmodic pain. |
IV meds of Morphine should be given | slowly over 4-5mins. Protect drug from light and freezing. |
Morphine adult dose | 5-20mg subq or IM Q4hr as indicated. IV admin range from 2-15mg/5mL |
Morphine Child dose | 0.1-0.2 mg/kg per dose subq q4hr max not to exceed 15mg. |
acetaminophen overdose antidote | Mucomyst! |
Silver sulfadiazine (Silvadene) is a | burn preparation. apply once or twice daily to a thickness of approx 1 1/16 inch. No dressing required. |
Timolol (Timoptic)is an | ophthalmic anti-glaucoma beta blocker. Use 1 drop .25% solution twice daily. |
Ophthalmic NSAIDs for cataracts | Voltaren, Ocufen, Acular, Profenal |
Special teaching with Cataract meds | minimize use of concurrent NSAIDs during topical therapy. Instruict to avoid covering lesion with occlusive dressing and to avoid applying sunscreen or cosmetics to the affected area. Advise t that it may take up to 1 mo for complete healing to occur. |
pantraprazole (Protonix) dosage | Adults dose: 40 mg delayed-release capsule once daily for 8wk also available as an IV infusion |
Protonix Indications | Erosive esophagitis a/w GERD. Decrease relapse rates of daytime and nighttime heartburn symptoms on pts with GERD. Atreatment of duodenal ulcers a/w Heliobacter pylori |
Protonix actions | Binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen. |
Protonix Adverse Effects | aha, abdominal pain, diarrhea, eructation, flatulence |
Protonix Pt teaching | take as directed for full course of therapy. No booze or aspirin, NSAIDS, or food that would irritate GI. REport black, tarryt stools; diarrheal or abdominal pain to health care professional IMMEDIATELY! |
The most common adverse reaction from heparin is | excessive bleeding and thrombocytopenia. |
Early signs of overdosage or internal bleeding of heparin include | bleeding from gums while brushing teeth, excessive bleeding or oozing from cuts, unexplained bruising or nosebleeds, and unusually heavy or unexpected menses (in women). |
Heparin is the anticoagulant of choice when what effect is needed? | immediate! |
Low-intensity coumadin therapy greatly decreases the risk of | stroke from nonrheumatic atrial fibrillation and has few side effects. |
Foods that interfere with the anticoagulant effect: | green leafy vegetables: broccoli, cabbage, collard greens, lettuce, spinach. or consumption of a nutritional supplement or multiV containing vita.K. |
Estrogens are used for | hormone replacement therapy in menopause or other conditions in which the natural estrogens are decreased, such as ovarian failure, primary amenorrhea, and oophorectomy. |
Hormone replacement therapy may | increase risk for cancers. |
levothyroxine (Levothroid, Synthroid, Unithroid) are thyroid supplements or replacements.. dosage: | synthetic prep is the drug of choice because effect is predictiable. Initial therapy is .05-.1 po daily with increase of .05-.1mg at 2 week intervals until effect is achieved. |
Levthyroxine Evaluation | Response to therapy is not immediate. Most pt.s begin to feel better within to weeks and the therapeutic results are often seen in 3 months. |
If side effects on a thyroid supplement occur | therapy will be withdrawn for 2-6 days and then restarted at a lower dosage. |
Pts over 50 are sensitive to throid hormones and should be monitored closely for | Cardiovascular disease before dosage is increased. |
Laboratory tests for serum T4 and TSH are used to confirm | hypothyroidism |
Levothyroxine is usually the drug of choice for | thyroid replacement |
Alpha Adrenergic blocking agent: | dapiprazole (ophthalmic prep) use 2 drops follwed 5 min later by an additional 2 drops. |
Dapiprazole is used to | reverse mydriasis (dilation) after eye examination. |
Loop Diuretics | act by blocking active transport of chloride, sodium, and potassium in the thick ascending loop of Henle |
POtassium-sparing diuretcis | increase the exrcretion of water and sodium but save potassium. |
Most popular Thiazide diuretic | hydrochlorothiazide (HydroDIURIL, Microzide) |
Most popular Loop diuretic | furosemide (Lasix) |
most popular Potassium sparkingdiuretic | spironolactone (Aldactone) |
digoxin (Lanoxin) USE | atrial flutter, atrial fibrillation, PAT, CHF |
digoxin (Lanoxin) ADVERSE REACTIONS | digitalis toxicity |
The elderly often have a reduced tolerance for | Digitalis. |
Digoxin (Lanoxin) is a | cardiotonic |