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patho 3
patho
Question | Answer |
---|---|
is a disturbance in the immunologic tolerance to self-antigens. | autoimmunity |
the most severe immediate hypersensitivity reaction | anaphylaxis |
most but not all common allergic reactions are mediated by IgE making them ___ reactions | Type 1 |
acting through H1 receptors contracts bronchial smooth muscles causing bronchial constriction increases vascular permeability causing edema and causes vasodilation increasing blood flow into the affected area. | Histamine |
hypersensitivity reactions generally are characterized by the destruction or altered function of a target cell through the action of antibody against an antigen on the cells plasma membrane. | Type 2 |
hypersensitivity include graft rejection tumor refection and the TB reaction and allergic reactions resulting from contact with substances such as poison ivy and metals. | Type 4 |
most common complez and serious of the autoimmune disorders | SLE |
the most characteristic autoantibodies produced in __ are against nucleic material | DNA |
seen more in women then men | SLE |
arthritis, vasculitis and rash, renal disease, hematologic abnormalities, and cardiovascular diseases. | SLE |
facial rash confined to the cheeks | SLE |
photosensitivity | SLE |
oral or nasopharyngeal ulcers | SLE |
serositis | SLE |
presence of antinuclear antibody (ANA) | SLE |
the presence of bacteria in the blood. | septicemia |
partial or complete absence of a thymus, partial or complete absence of the parathyroid gland and structural defects in the heart. | DiGeorge Syndrome |
in this syndrome penetrating the skin for routine blood tests, may potentially lead to fatal septicemia in the immunodeficient person. | DiGeorge Syndrome |
a defect in B-cell development results in lower levels of circulating immunoglobulins | hypogammaglobulinemia |
condition in which they are totally or nearly absent | agammaglobulinemia |
deficiencies develop after birth and are not related to genetic defects. | aquired immuno deficiencies |
deficient intake of ___ can profoundly depress both T and B cell function. | Zinc |
disorders are caused by some form of medical treatment. | Iatrogenic |
the best known example of an acquired dysfunction of the immune system | AIDS |
newborns who contracted the virus from their mothers across the placenta during delivery or through the milk during breast-feeding. | AIDS |
infect cells by binding to the surface of a target cell through a receptor and inserting their RNA into the target cell. | retroviruses |
is an antigen on the surface of helper T cells \that acts as the primary receptor for the HIV | CD4 |
virus causes a marked decrease in the CD4 cells. | AIDS |
early stage symptoms include influenza, night sweats, swollen lymph glands, diarrhea or fatigue. | AIDS |