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Endocrine I
Thyroid and Parathyroid
Question | Answer |
---|---|
What three hormones does the thyroid gland produce/secrete? | T3, T4, and calcitonin |
The _____ is located behind, close to, or embedded in the thyroid gland. It is responsible for producin/secreting ______. | Parathyroid Gland, Parathormone(PTH) |
The thyroid plays a major role in regulating _____________. | Metabolism |
Thyroid hormones increase metabolic rate, which _______ oxygen consumption and _____ production. | Increases, Heat |
Thyroid hormones give you ________. | Energy |
You have ______ in your diet to make thyroid hormones. | Iodine |
Increase in thyroid hormones do what to your heart rate? | Increase (Tachycardia) |
Why is levothyroxine (Synthroid)given? | Hypothyroidism |
What does Synthroid do to the heart rate? | Increases |
__________ disease is the most common type of hyperthyroidism. | Graves Disease |
Why is goiter associated with hyperthroidism? | The pituitary releases to much PSH and the thyroid is overstimulated. |
Why is goiter associated with hypothyroidism? | The thyroid is producing too much hormone. |
Bulging of the eyes that is often seen with hyperthyroidism is called ______ and is due to accumulation of fluid behind the eyeballs. | Exopthalmus |
After you have assessed the thyroid gland to be enlarged, what should your next action be? | Listen for a bruit |
In a patient with hyperthyroidism, the radioactive iodine uptake should be___________ | Increased |
In a patient with hypothyroidism, the radioactive iodine uptake shold be ___________ | Decreased |
List a few examples of medications that must be discontinued one to two weeks prior to a radioactive iodine uptake test and explain why. | Iodine, MVI, cough syrups, because they contain iodine and can affect results. |
PTU and Tapazole are antithyroid drugs which block the making of what? Must watch for signs of: | Thyroid Hormones(TH) Can cause agranulocytis and Thrombcytopenia; monitoe for s/s of infection, bleeding: monitor CBC |
Potassium Iodide, Lugol's solution, SSKI are iodine preparations which inhibit the production and release of Thyroid Hormones. What is another use of these iodide solutions | Reduces size and decreases vascularity of thyroid preop. Less chance of hemorrhage and thyroid storm. |
Why are Beta Adrenergic Blockers given to patients with hyperthyroidism? | Decrease sympathetic nervous systems: Cardiac, Tachycardia, palpations, nervousness, anxiety. Inderal |
Why is radioactive Iodine therapy given to patients with hyperthyroidism? | Destroys overactive thyroid cells |
Name two adverse affects to watch for in a person recieving radioactive iodine. | Hypothyroidism(destroys thyroid cells: usually need thyroid replacement) Thyroid Storm(overstimulation of the thyroid) |
For patients undergoing a total thyroidectomy, what do you teach them regarding medication regimen? | They will have to take thyroid hormone replacement for life |
Preop for a patient having a thyroidectomy, why do you want them in a euthyroid state? | Decrease vascularity(cance of hemorrhage) and decrease chance of thyroid storm(overstimulation during surgery) |
Why is it important to assess speach after surgery? | Assess for laryngeal nerve damage, laryngeal nerve and vocal cords run very close to thyroid |
After a thyroidectomy, what possition will your patient be in and why? | Semifowlers, 2 pillows to reduce edema |
What has happened when a person who has had a throidecomy complains of tingling around the mouth, toes and fingers? | Low calcium, accidental removal of the parathyroids |
If someone with hypothyroidism has a T3, T4, and TSH done, what would it show? Hyperparathyroidism has ____________levels of calcium (increase PTH) | Increased |
Hypoparathyroidism has _____________levels of calcium (decrease PTH) | Decreased |
Calcium and _____ have an inverse relationship. If you have an increase in calcium you will have a decrease in _____. | Phosphorus; phosphorus |
_______ acts as a sedative. | Calcium |
When will you see tetany (low calcium), muscle twitching, + Chovstecs and Trousseaus | Hypoparathyroidism(low calcium- irratability of muscles and nerves; hyperactive reflexes |
After a thyroidectomy, what must be in the room at all times? | Trach tray, suction equipment, oxygen, and calcium gluconate |
Low serum calcium levels _____ release of calcitonin to keep from lowering it more. | suppress |
Elevated serum calcium levels ______ the release of calcitonin to help lower calcium levels | increase |
Calcitonin makes strong bones by | Keeping calcium in bones and out of blood |
PTH makes weak bones by | Pulling calcium from the bones into the blood |
Pituitalery gland releases ______ from the _______ lobe. | TSH (Thyroid Stimulating Hormone), Anterior |
Why does hyperthyroid cause an increase in RBCs? | Because of the increase in O2 consumption, RBCs are needed to carry O2. |
Common type of hypothyroidism- | Hashimotos |
Extreme hypothyroidism- | Myxedema |
Most extreme hyperthyroidism- | Thyroid storm |
T3 & T4 regulate | basal metabolic rate |
when T3 & T4 levels are high | TSH release is inhibited |
when T3 and T4 is low | TSH is released so thyroid gland will produce and secrete T3 & T4 |
Dietary requirements for T3 & T4 production | food, water, protein, and iodine |
Goiter causes | Lack of iodine, tumors, inflamation, excess iodine or lithium |
Give ________and______for hypothyroidism. | Fluids and fiber |
Why take thyroid hormones in the a.m.? | because they give you energy |
When TH is given, monitor closely for.... | Angina, dyspnea, increased BP |
TH may increase.... | Blood glucose, digitalis, and anticoagulants, so there is a risk for bleeding. |
Myxedema manifestations | Hypothermic, decreased LOC, hypoventilation, acidosis, decreased glucose |
T3 & T4 are low, TSH is | High |
Hypoglycemia radioactive iodine uptake is | decreased |
Don't take TH with | Food |
pt and inr will_______ with use of TH | increase |
Patients who have overused narcotics and sedatives are at risk for | Myxedema coma |
mngmnt of myxedema | Maintain airway, hydration, levothyroxine, glucose IV, warm blankets, steroids |
Thyrotoxicosis | s/s of hyperthyroidism |
Hyperthyroidism causes increased metabolism which leads to | negative nitrogen ballance |
too much TSH = | hyperthyroidism |
Hyperthyroid=high T3 & T4, and _______ TSH | low |
Radioactive iodine uptake is read | 2 to 4 hours, and 24 hours |
wthith radioactive iodine uptake you should stop your meds containing iodine 1 week prior, why? | Because they affect the thyroid |
Hyperthyroidism diet | increase calories, protein and carbs because of the negative nitrogen ballance |
Drug therapy for hyperthyroidism | PTU, Tapazole, Beta Adrenergic Blockers, radioactive iodine therapy |
PTU and Tapazole are antithyroid drugs they.... | may take several weeks to become affective |
PTU and Tapazole can cause | Agranulocytosis and Thrombocytopenia |
Agranulocytosis | Low WBCs- risk for infection |
Thrombocytopenia | risk for bleeding (bruising/petichia) |
potassium iodide, lugol's, SSKI are used preop to | inhibit synthesis and release of hormones, and decrease vascularity of the gland.Avoid anything containing iodine |
Beta blockers (Inderal) don't do anything to the thyroid, but they help symptoms such as.... | sympathetic nervous system, nervousness, tachycardia, tremor, anxiety, heat intollerance |
After radioactive Iodene therapy | precautions for three days, watch urine |
What is the risk of radioactive iodine therapy? | to much thyroid destroyed, causes hypothyroidism. Overstimulation may cause tthyroid storm. |
signs of iodine toxicity | swelling of buccal mucosa, excessive salivation, coryza, skin eruptions in the mouth. |
coryza | head cold symtoms, mouth changes in taste etc. |
hypocalcemia or tetany | reduced PTH |
calcium gluconate | 1st line treatment for hypocalcemia (low PTH) |
Acute thytoiditis | Bacterial, fungi, parasitic, tx with abx |
subacute thyroiditis | viral, treat symptoms |
Chronic thyroiditis/Hashimoto's disease | if not treated can cause hypothyroidism. cannot produce thyroid hormone so must be given as treatment. |
Parathyroid Glands | Raise serum Calcium through negative feedback mechanism. |
Hyperparathyroidism too much sedative | serum phos drops/ bones get brittle tx with calcitonin avoid thiazide diuretics give phoshates and Fosomax |
parathyroidectomy | removal of 1 or 2 parathyroid glands keep calcium gluconate on hand in case of a drop in calcium. |
Hypoparathyroidsm Calcium too low in the blood | Spasms, tetany, bronchospasms, hyper DTRs Tx with calcium gluconate, calcium, high calcium foods avoid milk give amphogel |