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bi240 acute vs chron
GRCC BI240 Acute vs. Chronic
Question | Answer |
---|---|
which cells are involved in acute inflammation. | Neutrophils, macrophages, and lymphocytes if an immune response is involved. |
Cells involved in chronic | Lymphocytes, macrophages and fibroblasts (scar tissue) |
Which leukocyte is the first line of defense in the inflammatory process? | Neutrophil- it helps with acute inflamation. |
neutrophil | phagocytes in the early inflammation site where it ingests foreign invaders leaving behind pus. |
eosinophils | Allergic & parasitic reactions elevate these |
Releases chemicals that spread inflammation. | eosinphils |
basophils | Degranulates, releases histamine leading to inflammation. |
lymphocytes | Chief WBC in chronic inflammation. |
B- lymphs | produce antibodies |
T-lymphs | cell mediated immune response (activates macrophages, natural killers, t cells) |
mast cells | located in connective tissue |
what reacts to varioius stimuli to mpromote inflammation? | mast cells |
What does mast cells contain? | granules of heparin, serotonin, bradykinin & histamine) |
How long does it take mast cells to react? | Once released (degranulated) they act immeadiately. |
What stimulates mast cells to degranulate? | physical injury, Chemical agents (anaphylatoxins), IgE (allergies, hypersensitive reactions), and complement system. |
Chemical agent that stimulates the mast cell to degranulate. | anaphylatoxins |
What is the function of IgE? | it stimulates mast cells to degenerate and related to allergies, hypersensitivity reactions. |
Complement system consists of plasma proteins that stimulates what? | the mast cells to degenerate. |
Within the mast cell is histamine, these granules do what? | promotes vascular permability via vasodilation. |
mast cells contain neutrophil and eosinophil chemotactic factor that does what? | a biochemical substance that attracts leukocytes to the site of inflammation. |