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bi240 acute inflamma
grcc bi240 accute inflammation
Question | Answer |
---|---|
Acute inflammation response with a tissue injury | damaged mast cells and platelets release chemical mediators into the ECF and Blood. |
What are the immeadiate effects follwoing injury | histamine released first |
What are the later effects following injury | Leukotrienes and prostaglandins are released. |
What are chemical mediators? | they are messengers released from the mast cell and platelets. |
What do the chemical mediators (messengers) do? | They effect blood vessels and nerves. |
What are the names of the chemical mediators? | histamine, serotonin and prostaglandins, leukotrines. |
What do the chemical mediators do? | vasodilation |
what does vasodilation do? | increased blood flow and increased capillary permeability |
What happens once vasodilation sets in and cap permeability increases, chemotaxis triggers what? | Leukocytes move to site of injury |
Leukocytes are activated by chemotaxis and do what? | They collect along capillary wall resulting in margination (pavementing) or adhesion to the wall |
As leukocytes adhere to the capillary wall they diapedesis- which means what? | emigrate through seperations in capillary wall. |
As the leukocytes emigrate through capillary wall and then what? | Phagocytosis begins. |
Phagocytosis | removal of debris and prepares for healing. |