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bi240 antigen
grcc bi240 antigens and immune response
Question | Answer |
---|---|
Antigen is a foreign substance on surface of individual cells that stimulate | immune response leading to a molecule that can react with antibodies |
Self antigens | your immune system ignores or tolerates self cells. |
self antigens activate and regulate | the immune response and intercellular communications. |
self antigens are useful in detecting | changes in cell memebranes altered by viruses or cancer. |
antigenicity | the capacity to stimulate the production of antibodies |
antigenicity depends on | chemical structure, foreignness and complexity. |
Antigen binding to its appropriate antibody causes | agglutination, phagocytosis, neutralization. |
non-self antigens recognized as invader or as foreign and the response | production of antibodies and memory cells. |
Antibody | specific protein produced in humoral response to bind with antigen. |
autoantibody | antibodies attack self antigen; ones own body |
Antibodys located in | thymus, lymphatic and bone marrow. |
Thymus | site or maturation and proliferation of T lymphocytes |
Lymphatic tissue | contains many lymphocytes...filter body fluids, removes foreign matter, immune response |
bone marrow | source of stem cells, leukocytes, and maturation of B lymphocytes |
neutrophils | phagocytic WBC's, non-specific defense, active in inflammatory response |
basophils | WBC's. bind IgE, release histamine in anaphylaxis |
Eosinophils | WBC's participate in allergic responses |
Monocytes | WBC's migrate from teh blood into tissues to become macrophages. |
macrophages | phagocytize foreign material, process and present foreign material to lymphocytes that initiate immune response. |
mast cells | release chemical mediators such as histamine in CT |
B lymphocytes (B-Cells) | Humoral immunity activated cell leads to become antibody-producing plasma cell or memory B cell. |
plasma cells | develop from B lymphocytes, secrete specific antibodies. |
T lymphocytes (T cells) | WBC's cell-mediated immunity |
Cytoxic/killer T cells | destroy antigens, cancer cells, virus-infected cells |
memory T cells | "remember" antigen and quickly stimulate immune response on re-exposure |
helper T cells | activate B and T cells, control orlimit specific immune response |
NK lymphocytes | Natural killer cells destroy foreign cells, virus-infected and cancer cells. |