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HCR 240-Patho
Exam 2
Question | Answer |
---|---|
What are the cardinal signs of inflammation? | redness, swelling, heat, pain, and functional impairment |
Define swelling. | water in the interstitial space |
Fast fibers are also called ________ and they react ____________. | A-fibers; instantaneously |
Slow fibers are also called _________ and they _______________. | C-fibers; send signals when neighbors are injured |
What is vasodilation controlled by? | histamine |
Parenchymal cells | contain functioning cells of organ or body part |
Stromal cells | contain supporting connective tissues, blood vessels, and nerve fibers |
Labile cells | continue to regenerate, such as skin |
Stable cells | normally stop regenerating, such as the liver |
Permanent or fixed cells | cannot regenerate, replaced with fibrous scar tissue, such as nerve, skeletal and cardiac muscle cells |
Is there tissue loss in primary intention (1st) healing? | no tissue loss |
Is there tissue loss in secondary (2nd) intention healing? | yes, there is tissue loss |
What are the three phases of healing? | inflammatory, proliferative, and remodeling |
During the proliferative phase of healing, what cell is being used and what is it responsible for? | fibroblast; collagen and angiogenesis |
What are the three layers of the heart? | pericardium, myocardium, and endocardium |
What are the two layers of the pericardium? | parietal and visceral |
How many liters of blood are in a 70 kilo person? | 5 liters |
What is the MAP in the arteries? | 90-100 mm/Hg |
What is the MAP in the small arteries? | 60-90 mm/Hg |
What is the MAP in the arterioles? | 40-60 mm/Hg |
What is the MAP in the capillaries? | 26-32 mm/Hg |
What is the MAP in the veins? | 0-10 mm/Hg |
What is the formula to calculate cardiac output (CO)? | heart rate times stroke volume (HR x SV) |
What is cardiac output (CO)? | the amount of blood ejected from the left ventricle in the aorta in one minute |
What is the normal cardiac output (CO) in a 70 kilo person? | 5,040cc/min |
What is stroke volume (SV)? | the amount of blood ejected from the left ventricle in one beat |
What is the formula to calculate stroke volume (SV)? | endiostolic volume minus ensystolic volume (EDV-ESV) |
What is endiostolic volume (EDV)? | the amount of blood in the left ventricle at the end of diastole |
What is ensystolic volume (ESV)? | the amount of blood in the left ventricle at the end of systole |
What is normal stroke volume (SV) in a 70 kilo person? | 70cc/beat |
What is the formula to calculate ejection fraction (EF)? | stroke volume divided by endiostolic volume (SV÷EDV) |
What is ejection fraction (EF)? | the percentage of blood that was in the left ventricle at the end of systole that was ejected into the aorta |
What is a normal ejection fraction (EF)? | 65-85% |
What two things affect endiostolic volume (EDV)? | cardiac preload and myocardial distensibility |
What two things affect ensystolic volume (ESV)? | cardiac afterload and myocardial contractility |
What is cardiac preload? | volume of blood in left ventricle at the end of diastole |
What is cardiac afterload? | resistance to ejection from the chamber of the heart (left ventricle) |
What is myocardial contractility? | speed and force of contraction |
What is myocardial distensibility? | willingness of myocardium to stretch |
What influences myocardial distensibility the most? | oxygen status (ATP status) |