Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

NURS 572 -55

hematopoeitic growth factors

QuestionAnswer
hematopoietic growth factors treat for RBC, WBC
thrombopoietic growth factors treat for platelets
how must all hematopoietic growth factors be admin parentarally
epoetin-alpha MOA recomb DNA --> RBC production. Need essential Fe, Folic Acit, Vit B12
indications for epoetin-alpha chronic renal failure, HIV +, chemorx pts, anemic pts facing surgery
Epoetin-alpha ADRs HTN (increased Hgb) --> MI, CVA, HF very rare autoimmune red cell aplasia
epoetin-alph monitoring Hgb should be 10-12 g/dL, monitor bp q 4. May require anti-HTN med
Darbepoetin-alpha modified epoetin for double the half-life of 48 hours
Methoxypolyethylene glcol epoetin-beta modified epoetin lasting much longer, q2 week admin
Filgrastim-G-CSF full name filgrastim granulocyte colony stimulating factor
filgrastim-G-CSF indications to elevate neutrophil counts in cancer pts EXCEPT myeloid cancers
Filgrastim - G - CSF ADRs bone pain, leukocytosis (increases to 100,000)
filgrasti - G - CSF monitoring monitor CBC, temp, infection, bone pain
Pegfilgrastim peglated with polyethylene glycol to increase half life, otherwise same as filgrastim
sargramostin GM-CSF full name granulocyte + macrophage/monocyte colony stimulating factor
Sargramostin GM CSF indications bone marrow transplant pts, to increase neutrophils, macrophages/monocytes
sargramostin GM CSF ADRs diarrhea, weakness, rash, bone pain, leukocytosis and/or thrombocytosis
oprelveken IL-11 full name oprelvekin interleukin-11
oprelvekin IL-11 MOA thrombopoietic growth factor stimulates megakaryocytes and maturation
oprelvekin IL-11 indications for myelosuppresive chemorx to minimize thrombocytopenia, decreasing the need for platelet transfusion
oprelvekin IL-11 ADRs #1 Na/fluid retention --> 15% increase in plasma volume --> peripheral edema --> HF
oprelvekin IL-11 ADRs #2 cardiac dysrthythmias, blurred vision, papilledema, rarely death
Created by: lorrelaws
Popular Nursing sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards