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Psychiatric Meds

Psychiatric Medications Review - Psych Mental Health Nursing - generic names

QuestionAnswer
Atypical antipsychotics Clozaril, Risperidal, Seroquel, Zyprexa, Abilify, Geodon, Invega, Latuda, Saphris, Fanapt
Anti-Manic & Mood Stabilizing Drugs Lithium, Depakote, Lamictal, Tegretol, Trileptal
Tricyclic Antidepressants Anfranil, Elavil, Norpramin, Pamelor, Sinequan, Tofranil,Vivactil
SSRIs Prozac, Paxil, Celexa, Zoloft, Luvox, Lexapro, St. John's Wort
MAOIs Marplan, Nardil, Parnate, EMSAM-Patch
SNRI Effexor, Pristiq, Cymbalta
Benzodiazepines/ Anxiolytics Ativan, Klonopin, Librium, Tranxene, Valium, Xanax
other compounds Wellbutrin
Typical Antipsychotics Haldol, Mellaril, Prolixin, Stelazine, Thorazine, Moban, Loxitane, Serentil, Trilafon,
EPS Side Effect Treatment Agents Artane, Benadryl, Cogentin, Symmetrel
Non-Benzodiazepine- Anxiolytics Buspar, Inderal, Kava-Kava, Vistaril
Hypnotics & Herbals Ambien, Desyrel, Lunesta, Melatonin, Restoril, Valerian, Sonata, Rozerem
Substance Abuse Related Drugs Antabuse, Campral, Catapress, Methadone, Suboxone, Topamax
CNS Stimulants- ADHD Treatment Adderall, Focalin, Ritalin, Strattera, Vyvanse
Nursing Interventions for Atypical Antipsychotics Blood Pressure Checks, BMI measurements, blood glucose, lipids, monitor for hyperglycemia, assess for sedation or hypotension
Atypical Antipsychotics Side Effects risk of metabolic syndrome, increased weight, blood glucose, triglycerides, hypotension, sedation, dizziness
Tricyclic Antidepressants Side Effects dizziness, drowsiness, diarrhea, dry mouth, urinary retention, and orthostatic hypotension serious adverse reactions are paralytic ileus, acute renal failure, hypertension, and hypertensive crisis, depending on the specific product.
Tricyclic Antidepressants Nursing Interventions Blood Pressure, pulse, Monitor laboratory studies, weight increase, appetite increase, mental status, mood, sensorium, affect, suicidal tendencies,Urinary retention, constipation
Which medication is indicated for Parkinson's dementia (mild to moderate) Rivastigime
Which medication is FDA indicated for Parkinson's disease psychosis? Pimavanserin (Nuplazid)
What is the MOST effective treatment for Parkinson's? Levodopa/Carbidopa (Sinemet)
What is an unpleasant side effect of amantadine (Symmetrel)? Confusion/memory problems
What two neurotransmitters are regulated in Parkinson's disease with anitcholinergics? Dopamine and Acetylcholine
Which medication can be used in all stages of Alzeheimer's Donepezil (Aricept)
Should galantamine (Razadyne) be used with renal impairment? Should be used with caution in those with renal and hepatic impairment.
What is the MOA of memantine (Namenda) NMDA glutamate receptor
What is the Aricept/Namenda combination medication Namzaric
Are there any FDA approved medications for dementia related behavioral distrubances? No, everything is off-label.
What test is required prior to starting Nuedexta? ECG
Which medication is FDA approved for anorexia nervosa No FDA medication approved; can use SSRIs and antipsychotics off label for the treatment of comorbid depression/anxiety/mood
Which medication is FDA approved for bulimia Fluoxetine (Prozac) 60-80mg daily
Which medication is FDA approved for binge eating disorder? Lisadexamfetamine (Vyvanse).
Can you use Vyvanse in those with hyperthyroidism? No, contraindicated in hyperthyroidism and glaucoma
What two medications are used for alcohol abstinence acomprosate (Campral) and disulfiram (Antabuse)
How long should a client be abstinent of alcohol before starting disulfiram (antabuse)? at least 12 hours from last drink
Should a person with ESRD be prescribed acomprosate (Campral) No, this medication is contraindicated in renal impairment
What two medications are used for etoh dependence? Nalmefene (Selincro) and Naltrexone (Vivitrol)
What two class of medications are used for etoh withdrawal? Benzodiazepines and alpha 2 agonist
What can happen when methadone (Dolophine) is mixed with other CNS depressants? Death
What medical issues are contraindicated with methadone (Dolophine) use? Respiratory depression, acute or severe bronchial asthma, gastrointestinal obstruction including a paralytic ileus
What is the MOA of buprenorphine (Suboxone)? Suboxone is an opioid partial agonist that binds to opiate receptors, preventing exogenous opioids from binding.
How long must a client be clean before starting naltrexone (Vivitrol)? The client must be opioid free for 7-10 days before starting treatment and must be confirmed by drug screens
What are all the forms of NRT? Gum, Patch, Nasal Spray, and Inhaler.
What part of the brain is thought to be involved with ADHD? Prefrontal Cortex
Which neurotransmitters are involved with ADHD? Dopamine and norepinephrine
What measure tools are used in diagnosing ADHD? Connors and Vanderbilt
What are the types of ADHD? Combined, predominately inattentive, and predominately hyperactive-impulsive
Symptoms of impulsivity appear to involve which area of the brain? Orbitofrontal cortex
What is the mechanism of actions of stimulants? Increasing norepinephrine and dopamine by blocking reuptake
What part of family medical history is extremely important before prescribing stimulants? Cardiac disease history
What medical condition is contraindicated with stimulant use? Glaucoma
What can delay peak action of stimulants for 2-3 hours? Taking the stimulant dose with food
What test and vitals are important to monitor with stimulants ECG, BP, height, weight
What medical conditions are amphetamine used in caution with? Hepatic and cardiac impairments
Which medication condition is contraindicated with use of Vyvanse? Hyperthyroidism
What labs should be monitored periodically with Vyvanse? CBC, platelets, and LFTs
People that lose their appetite for dinner may benefit from which two stimulant options? Metadate CD and Ritalin LA
What is a rare side effect of methylphenidates? Priapism
Which SNRI is FDA approved for ADHD ages 6 and older? Straterra
How long can it take for Strattera to be effective? 2-3 months
What is the MOA of clonidine? Alpha 2 agonist but also norepinephrine receptor agonist
Which enzyme metabolizes guanfacine? CYP450 3A4
Which antipsychotic is FDA indicated for Autism related irritability ages 5-16? Risperdal
What is designed to provide guidelines in prescribing high risk medications in the elderly? Beers criteria
How does a practitioner decide on medications in pregnancy? Risk vs benefit discussion
What is recommended to supplement with Lamictal if taken when pregnant? Extra folic acid
What is lithium levels so important to monitor frequently in pregnancy? Due to fluid shifts
What the “D”s in the D approach in deprescribing? Diagnosis, dangerous, dosages, duplicate, deficient, desire, and duration
Which SSRI is FDA indicated for bulimia nervosa? fluoxetine (Prozac)
Which two SSRIs are FDA approved for treating children with MDD? i. Escitalopram (Lexapro) 12 and up, ii. Fluoxetine (Prozac) 8 and up
Which SSRI is not FDA approved for MDD or depression? Fluvoxamine (Luvox) (OCD)
Which SSRI should be dosed at night due to sedation? Paroxetine (Paxil), long 1/2 life life
Which SSRIs are FDA indicated for PMDD? There are 3 of them. i. Fluoxetine (Prozac), ii. Paroxetine (Paxil), and iii. Sertraline (Zoloft)
Which enzyme does Duloxetine (Cymbalta) inhibit? And can you remember from week one what other substance inhibits this exact enzyme. CYP450 1A2 and the substance is cigarettes (nicotine)
Which SNRI is indicated for MDD and neuropathic pain? Duloxetine (Cymbalta)
What OTC medication can reduce clearance of Venlafaxine (Effexor)? Cimetidine (Tagamet HB)
What vital signs should be assessed before initation of Levomilnacipran (Fetzima)? i. Heart rate and ii. blood pressure
Which SNRI is not FDA indicated for mental illness disorders? Milnacipran (Savella)
Which antidepressant is contraindicated with epilepsy or eating disorders? Buproprion (Wellbutrin)
Which class of antidepressants are known for a three ring structure? TCA’s
What is the biggest concern with prescribing TCA’s to a suicidal client? Overdose, this should be not given to a suicidal client if you can avoid, but if necessary, no more than a weeks supply should be considered; only takes 7x normal dose for OD; bicarbonate is needed to reverse
What ingredient in food should be avoided in those taking a MAOI? Tyramine
Which OTC class of medications should be avoided with MAOIs? Cold medicines
Which pain medication can increase risk for seizures in those taking antidepressants? Tramadol (Ultram)
Which populations require a lower recommended starting dose of antidepressants? i. Elderly and ii. children
What is the black box warning for antidepressants? May increase risk of suicidality, especially in young adults
What are symptoms of serotonin syndrome? i. Shivering, ii. Hyper-reflexia/ myoclonus iii. Increased temperatures, iv. Vital sign instability, v. Encephalopathy/altered LOC, vi. Restlessness, vii. Sweating
How many days must the client wait after discontinuation of a MAOI before starting a SSRI? 14 days
What labs are necessary prior to starting Carbamazepine (Tegretol)? i. CBC, ii. LFTs, iii. kidney and iv. thyroid function.
If taking Lamotrigine (Lamictal) what is the most deadly side effect? And how many days can a patient miss before starting back at initial dosing? i. Stevens Johnson Syndrome. ii. 5 days or more must restart at initial dosing.
What is the therapeutic range for lithium? i. 0.6-1.2mEq/L
What are symptoms of severe lithium toxicity? i. Hyperthermia, ii. hypotension, iii. seizures, iv. renal failure, v. coma, vi. death
What is the therapeutic range for Valproate (Depakote)? 50-125ug/mL
Which neurotransmitter is directly related to Alzheimer's and impaired memory? Acetylcholine
Which amino acid has excitatory properties, and an increase presents as bipolar affective disorder? Glutamate
Which neurotransmitter reduces arousal, aggression, and anxiety? GABA
Which neurotransmitter is related to extrapyramidal side effects and prolactin dysregulation? Dopamine
Which neurotransmitter is related to depression and anxiety and is found in the brain as well as the GI system? Serotonin
What is the outermost layer of the cerebrum? Cerebral Cortex
What is the largest part of the brain? Cerebrum
What is the newest identified lobe of the brain? Insula
Wrinkled ball of tissue that helps coordinate movement? Cerebellum
Name the three parts of the brainstem i. Midbrain, ii. medulla oblongata, and iii. pons
Thinking, planning, organizing, problems solving, and short-term memory are in which lobe? Frontal
Temperature, taste, touch, and movement are process in which lobe of the brain? Parietal
Which brain lobe process primarily vision and has been linked to visual hallucinations? Occipital
Which lobe of the brain processes memories, integrating them with sensations of taste, sound, sight, and touch? Temporal
Which lobe of the brain is associated with conscious desires and decodes bodily states? Insula
What structure processes all incoming information except for smell? Thalamus “Hal”.
Which structure of the brain processes smell and attaches emotions to stimuli? Amygdala “Amy"
What structure of the brain functions as the library/google, memory center? Hippocampus “Campus”
Which structure is the hormone monitor and tells others which hormones are needed? Hypothalamus ”little Hal” –he is bossy!
What structure is considered the danger protector and stimulates hormones? i. Pituitary gland and ii. basal ganglia “bee gees”
Molecular changes produced by a drug when binding to receptor site is termed? Drug action
What are the route, absorption, distribution, binding, inactivation, and excretion considered? Factors of drug action
What is the pharmacokinetic parameter that is defined as the time for the drug concentration in the plasma to be reduced by 50%? Half life
What is calculated by adding 4-5 half life’s of a medication? Steady state
What is a common enzyme family that break down hormones and medications? PYC450
Which benzodiazepine is FDA indicated for Generalized Anxiety Disorder and Panic Disorder? Alprazolam (Xanax)
Which enzyme most commonly metabolizes benzodiazepines? CYP450 3A4
Benzodiazepines should not be tapered any faster than 3 day increments with specific dose reduction. True or False True
Benzodiazepines are habit forming. True/False true
5. There are safer options for the treatment of anxiety, especially in those with a history of drug abuse, compared to benzodiazepines. True or False true
Insomnia is common in those with mental illness. True/False true
Which stage of sleep does the body temperature decrease? stage 2
What class of insomnia medications are known to cause sleep driving? Hypnotics
Which hypnotic is only FDA approved for short term insomnia? Zaleplan (Sonata)
What is the mechanism of action for Ramelteon (Rozerem)? Ramelteon (Rozerem) is a melatonin receptor agonist.
Which receptor/neurotransmitter is related to EPS? Dopamine, D4
How do we know if a side effect is related to the medication prescribed? a. Practitioners should be aware of the receptor the drug binds to and of the possibility of the client exhibiting those side effects relating to that receptor.
Which antipsychotics are associated with the least side effects? Atypical antipsychotics
Which atypical antipsychotics could be passed in a bowel movement by the patient intact? Paliperidone (Invega)
What aspect of client care would indicate the need of a long-acting injection? History non-compliance
NMS is common. True/False False
NMS is life threatening. True/False True
What is the first thing the practitioner should do with the medications if NMS is suspected? Discontinue the antipsychotic
Should NMS be treated outpatient? No, medical support is necessary
NMS only happens in the first few days of starting antipsychotics. True/False FAlse
In order to minimize side effects, practitioners should avoid multiple simultaneous medication changes. True/False True
What can help sweating with antidepressants? Clonidine (Catapress) or Benztropine (Cogentin)
What is bruxism? Bruxism is involuntary grinding and gnashing of teeth
What class of medications treat acute dystonia? Anticholinergics
What medication works for priapism? None, priapism requires an emergency room visit
Created by: TBess
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