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pharm test 3
pharm antianginal agents ch. 23
Question | Answer |
---|---|
nitrates/nitrites | -cause vasodilation d/t relaxation of smooth muscles -potent dilating effect on coronary arteries -used for prevention and treatment of angina -vasodilation results in reduced myocardial oxygen demand |
nitrates/nitrites | -nitrates cause dilation of both large and small coronary vessels -result: oxygen to ischemic myocardial tissue -nitrates alleviate coronary artery spasms **when someone takes nitroglycerin they should be laying down b/c they will get a drop in BP |
nitroglycerin | -rapid acting -large first pass effect with oral forms **used for acute relief of angina |
nitrates: Long-acting | -isosorbide dinitrate -isosorbide mononitrate **used for prophylaxis in situations that may provoke angina; longterm prophylaxis of angina |
nitrates side effects | -headache -tachy, postural hypotension, dizziness |
Beta blockers | -atenolol -metoprolol -propanolol -nadolol **YOU DO NOT ABRUPTLY STOP BETA BLOCKERS** |
calcium channel blockers | -verapamil (calan) -diltiazem (cardizem) -nifedipine (procardia) **they reduce myocardial contractility (negative inotropic action)** |
calcium channel blockers | first line agents for treatment of angina, HTN, supraventricular tachycardia -prevent future attacks -popular for lowering BP in A.A |
calcium channel blockers side effects | hypotension, constipation, edema **constipation is a common problem; instruct pt. to take in adequate fluids and eat high-fiber foods |
beta-blockers | inform pts that these meds are for long-term prevention of angina, not for immediate relief |
a pt. has a new perscription for transdermal nitroglycerin patches. the nurse teaches the pt that these patches are most appropriately used | to prevent the occurrence of angina |
a nurse with adequate knowledge about the administration of IV nitroglycerin will recognize that which statement is correct? | IV nitroglycerin must be protected from exposure to light through the use of special tubing |
which statement by the pt. reflects the need for additional pt. education about the calcium channel blocker diltiazem (cardizem)? | "i can take this drug to stop acute anginal attacks" |
while assessing pt. with angina who is starting beta blocker therapy, the nurse is aware that the presence of which condition may be a problem if these drugs were used? | asthma |
a 68 y/o man has been taking the nitrate isosorbide dinitrate for 2 years for angina. he recently has been experiencing erectile dysfunction and wants a perscription for sildenafil (viagra). which response would the nurse most likely hear from the doc | "taking sildenafil with nitrate may result in severe hypotension, so a contraindication exists" |
the nurse is reviewing drug interactions with a male pt. who has a prescription for isosorbide dinitrate (isordil) as treatment for angina symptoms. which substances listed could potentially result in drug interaction? | -a glass of wine -sildenafil(viagra), an erectile dysfunction drug -carvedilol (coreg), a beta blocker |