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NURS 472 Pharm 33
Pharm Ch 33 bipolar disorder BPD
Question | Answer |
---|---|
Two phases of BPD we treat | manic phase and depressive phase |
classes of drugs to treat BPD | mood stabilizers --- antidepressants --- BNZ benzodiazepines --- antispychotics |
How are classes of BPD drugs prescribed | Always involves a mood stabilizer for the manic phase. Mood stabilizer used in combination with antidepressant and/or short-term BNZ and/or antipsychotic |
Which class of BPD is never given alone | never give antidepressants alone in BPD |
which class of BPD is never used long-term | never use BNZ long term |
which class of BPD can also be used during acute mania | antisphychotics can also be used |
Name 3 mood stabilizers always given primary | lithium, valproic acid, carbamazepine |
which mood stabilizer has drug interactions related to renal excretion like Na | lithium has these interactions |
which mood stabilizer is preferred for euphoric mania | lithium is preferred |
which mood stabilizer given BID/TID with SEs of polysyspia, polyuria, tremor, hypothyroidism | that would be lithium |
which mood stabilizer is preferred for its rapid onset, also alters GABA | valproic acid |
which mood stabilizer is preferred for all manias EXCEPT euphoric | carbamazepine |
which mood stabilizer has least ADRs | carbamazepine |
name 3 antidepressants for depressive phase | buproprion (atypical), venlafaxine (atypical/HTN) and SSRIs |
example of BNZ that can be used for short term acute manic phase | lorazepam |
Give me the list of 2nd generation antipsychotics that can be used during acute mania | ***olanzapine, quetiapine, respiradone, ziprasidone, aripiprazole |
of antipsychotics, which is only one approved for use AFTER manic phase | olanzapine |
which antipsychotic SHOULD NOT be used | clozapine, due to agranulocytocis/CBC-diff |