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Pharmacology Test 1
Muscle Relaxants
Question | Answer |
---|---|
Methocarbamol (Robaxin) | Central acting skeletal muscle relaxant.Uses: adjunct for relief of spasm and pain in MS conditions such as Tetanus. SE: seizures, bradycardia, nausea, brown/green urine, hemolysis, elevated hemaglobin, rash, anaphylaxis, angioneurotic edema. |
Methocarbamol Teaching: | pt should taper to avoid SE, green/brown urine, no ETOH, fall risk secondary to dizziness, drowsy, avoid OTC cough, antihistamines |
Cyclobenzaprine (Flexeril) Skeletal muscle relaxant, central acting | adjunct relief of muscle spasm and pain in MS conditions. Fibromyalgia(off label.SE: dizziness, drowsiness,dysrhythmias, nausea/emesis,urinary retention, rash. Assess pain, allergies,severe weakness in ext., do not crush, break, or chew ext release tab |
Cyclobenzaprine Teaching | should be tapered over a week,no etoh,avoid activity hazardous, avoid OTC cough, antihistamines, use gum or frequent sips of water for dry mouth |
Diazepam(Valium)- Antianxiety, anticonvulsant, skeletal muscle relaxant, central acting | adjunct skeletal muscle relaxant, rectally for acute seizure ppx.SE:dizziness,drowsiness,ECG changes,tachy, neutropenia, rash respiratory depression, crosses blood-brain barrier |
Diazepam Teaching | Assess:Orthostatic BP, P, RR, degree of anxiety, mental status, physical dependency Give with milk or food, may crush, gum for dry mouth, reduce opioid by 1/3, fall risk, not to be used for anxiety more than 4mos, habit forming, avoid OTC, avoid driving |
Dantrolene sodium (Dantrium) Skeletal muscle relaxant, direct acting | Uses: spasticity in MS, CVA, SPI,CP,malignant hyperthermia. SE:dizziness, seizures, low BP, hepatic injury, n/v, urinary frequency, cbc changes,rash,photosensitivity, Black Box Warning, do not crush or chew, with meals, fall risk, eval response |
Dantrolene sodium Teaching | Assess ECG, I&O,hepatic fxn,severe weakness, tolerance, taper,dc after 6wks,avoid driving,avoid otc/etoh, use sunscreen |
Baclofen (Lioresal) Skeletal muscle relaxant, central acting | uses: spasticity in spinal cord injury, MS,unlabeled:neuropathic pain, trigeminal neuralgia. SE: dizziness,seizures,cns depression,hypotension, n/v, dyspnea, assess BP, wt,blood glucose, decreases seizure threshold,I&O,allergic rxn,severe weakness,toler |
Baclofen (Lioresal) Teaching | taper,no etoh,avoid hazards,avoid OTC, notify provider if nausea, h/a,tinnitus,insomnia,confusion,painful urination, may require 1-2 months for response |