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Microbiology VII

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show Typhoid fever: bacteria= Salmonella typhi typhus: bacteria=Rockettsia prowaseklii (epidemic), tphi (endemic), tsutsugamushi (scrub typhus)  
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show just nucelocapsid and genome  
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What is an enveloped icosahedral viral structure?   show
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What is an enveloped helical viral structure?   show
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show exchange of genes b/w 2 chr by crossing over in regions with base pair homology  
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What is viral reassortment?   show
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What is viral complementation?   show
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What is viral phenotypic mixing?   show
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show induce both humoral and cell mediated immunity. can revert on occassion. no booster. dangerous to give to ICPt and their close contacts  
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show only humoral, so might need booster  
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What viruses have live attenuated vaccines?   show
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show LIVE! See SMALL YELLOW CHICKENS get vaccinated with SABIN's and MMR!  
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show Rabies, Influenza, Salk Polio, HAV vaccine  
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What is a mnonic for the killed virus vaccines?   show
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show HBV (HBsAg, HPV (6,11,16,18)  
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show parvovirus  
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show pailloma, polyoma, hepadnavirus (circular)  
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show reoviridae  
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What are 7 positive ssRNA viruses?   show
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What is the mnemonic for the +ssRNA viruses?   show
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Which types of viruses have genomes which are infectious on their own?   show
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show retroviruses, 2 identical ssRNA molecules  
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Where do DNA viruses replicate? What is the exception?   show
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Where do RNA viruses duplicate? What is the exception?   show
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show Calcivirus, Picronavirus, Reovirus, Parvovirus, adenovirus, Papilloma, Polyoma virus  
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What is a mnemonic for the naked viruses?   show
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show usually plasma membrane when they leave. Except herpesvirus which gets it from the nuclear membrane  
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show Hepadna, Herpes, Adeno, Pox, Parvo, Papilloma, Polyoma  
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What is a mnemonic for the DNA viruses?   show
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What are the general charactersitics of DNA viruses?   show
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Which virus is the exception to the rule that DNA viruses are ds and linear?   show
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What is the exception to the rule that all DNA viruses are icosahedral and replicate in the nucleus?   show
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show has an envelope, dsDNA  
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What does HSV-1 cause? (3)   show
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show genital (some oral) lesions  
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show chickenpox, zoster(shingles)  
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What diesease does EBV(HHV-4) cause? (3)   show
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show infects IcPT(espAIDS retinitis), transplant recipient, congenital defectos (SIGHT-omegalovirus)  
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show roseola (exathem subitum)  
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What does HHV-8 (KSHV) cause?   show
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What is the enveolpe and DNA structure of Hepadnavirus?   show
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What disease does HBV cause? Is there a vaccine? What is interesting about it's enzymes?   show
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What is the enveope and genome of adenovirus?   show
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show febrile pharyngitis (ST, acutue hemorragic cystitis), pneumonia, conjunctivitis- pink eye(watery)  
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What is the envelope and genome structure of parvovirus?   show
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show aplastic crises in SCA, slapped cheek rash in children-5th disese, RBC destructuion in fetus causing hydrops fetalis, pure RBC aplasia and RA in adults  
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show no envelope, dsDNA circular  
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What does HPV 1,2,6,11 cause?   show
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show CIN, cervical cancer  
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What HPV strains is there a vaccine for?   show
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show no envelope. dsDNA circular  
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show progressive multifocal leukoencephalopathy (PML) in HIV  
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What does BK polyomavirus cause? who gets it?   show
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show enveloped dsDNA linear virus. largest  
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show cow pox, milkmaids blisters  
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What is molluscum contagiosum and what virus family causes it?   show
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Where is HSV-1 found latent? what disease does it cause?   show
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show secretions or saliva  
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What does HSV-2 cause and where is it latent?   show
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show sexual contact, perinatal  
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What disease does VZV cause? where does it go latent?   show
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show cuases infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma. Latent in B cells  
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show respiratory secretions  
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show saliva, respiratory secretions  
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What does CMV cause, where does it go latent?   show
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show owl's eye inclusions  
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How is CMV spread?   show
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high fevers for several days that can cause seizures. followed by diffues macular rash. esp in kids. Pathogen?   show
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show spread by sexual contact. causes Kaposi's sarcoma  
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What is a Tzanck test and what pathogens does it assay for? What else might be seen?   show
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What is a mnomonic for the things detected by a Tzanck test?   show
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show EBV. atypical lymphocytes are not infected B cells but rather reactive cytotoxic T cells  
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What is a monospot test? what does it mean if positive?   show
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