Ch 9 Mucus controlling drugs
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Abhesive | show 🗑
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Elasticity | show 🗑
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show | Medication meant to increase the volume or hydration of AW secretions.
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show | Macromolecular description of pseudoplastic material having both viscosity and elasticity.
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Glycoprotein | show 🗑
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show | The principal constituent and high molecular weight glycoprotein, it gives mucous its physical/chemical properties such as viscoelasticity.
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Mucoactive agent | show 🗑
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show | Medication that increases cough ciliary clearance of respiratory secretions.
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show | Medication that degrades polymers in secretions. Classic mucolytics have free thiol groups to degrade mucin, and peptide mucolytics break pathologic filaments of neutrophil-derived DNA or actin in sputum.
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Mucoregulatory Agent | show 🗑
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Mucospissic Agent | show 🗑
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show | Secretion, from surface goblet cells and submucosal glands, composed of water, proteins, and glycosylated mucins. The glycoprotein portion of the secretion is termed mucin. Mucus (noun) is the secretion; mucous (adjective) is the cell or gland type.
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show | Sugar that is the individual carbohydrate unit of glycoproteins.
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show | Purulent material in the AW. From the greek word from inflammation. When expectorated, phlegm is called sputum.
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Rheology | show 🗑
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Sol | show 🗑
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Sputum | show 🗑
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Viscosity | show 🗑
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Mucoactive therapy should be considered when? | show 🗑
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What does Mucus do? | show 🗑
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show | Entrap microorganisms, inhibiting chronic bacterial infection and biofilm formation.
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show | N-acetylcysteine (NAC)
Dornase Alpha
Aqueous aerosols: Water, Saline
Hyperosmolar (7%) saline
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show | Bronchitis, efficacy not proven for any dose of NAC for an lung disease
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show | CF
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show | Sputum induction, secretion, mobilization
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Indications for Hyperosmolar (7%) saline | show 🗑
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show | SVN: 3-5mL of 10% or 20%
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Dosages for Dornase alpha | show 🗑
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Dosages for Aqueous aerosols: Water, Saline | show 🗑
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Dosages for Hyperosmolar (7%) saline | show 🗑
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Brand Names for N-acetylcysteine (NAC) | show 🗑
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Brand Names for Dornase alpha | show 🗑
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Brand Names for Aqueous aerosols: Water, Saline | show 🗑
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Brand Names for Hyperosmolar (7%) saline | show 🗑
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The AW secretion consists of? | show 🗑
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show | Surfactants
Beta agonist agents
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What do Epithelial ion do in the AW? | show 🗑
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show | Very little intact mucin.
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What does a CF AW consist of? | show 🗑
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What are the physical properties of mucus? | show 🗑
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show | NAC (Mucomyst), Dornase alpha, and hypertonic saline.
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Classic mucolytics | show 🗑
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What drug does not improve mucus clearance when given as an aerosol and should not be used as a mucoactive agent? | show 🗑
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show | Sodium Ampicillin
Amphotericin
Erythromycin lactobionate
Tetracyclines (tetracycline oxytatracycline)
Aminoglycosides
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What are Potassium iodide and glycerol guaiacolate considered? | show 🗑
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show | inhaled anticholinergics such as atropine
Ttricyclic nucleotides
Phospholipids
Antiproteases
gene therapy
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What do studies show about long term use of ipratropium bromide are associated with? | show 🗑
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AD technique incorporates what? | show 🗑
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With IPV | show 🗑
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show | large volume variable frequency are pulse delivery system attached to an inflatable vest worn by PT.
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show | be taught as many mucus controlling therapy techniques possible to control their condition.
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