Introduction to Renal Pathology
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| Lamination in the GBM at EM is diagnostic of ? | show 🗑
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| What are cryoglobulins | show 🗑
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| show | Adult polycystic disease
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| What are extra-renal problems associated with Alport disease | show 🗑
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| What is the result of hyperfiltration through select nephrons due to persistent decreased regional blood flow | show 🗑
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| Is the charge of the glomerular filter positive or negative | show 🗑
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| show | increased cholesterol and increased a2 globulin
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| show | Minimal Change Disease
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| Minimal Change Disease is associated with what marker | show 🗑
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| When you see "fusion" of epithelial cell foot processes think? | show 🗑
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| If you have a chiild with minimal change disease and they do not respond to steroids think? | show 🗑
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| Nephrotic syndrome with microscopic hematuria, later creatinine rise, black>white patients affected, poor response to steroids? | show 🗑
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| Why might an early biopsy of focal segmental glomerulosclerosis miss the diagnosis | show 🗑
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| show | IgM and C3 in the sclerotic lesions in the glomerulus
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| What is the etiology of Membranous Nephropathy | show 🗑
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| show | On silver stain you see highlights of spikes of GBM between the immune deposits
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| show | 4th or 5th decade rare in children
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| What do you see on Immunofluorescence with membranous nephropathy | show 🗑
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| show | In Stage I patients respond to corticosteroid in Stage II 50% respond to steroid treatments
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| show | Kimmelstiel-Wilson Disease (bad prognosis)
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| Kimmelstiel Wilson Disease is often associated with what retinal finding | show 🗑
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| What is the earliest change noted in Diabetic Glomerulosclerosis | show 🗑
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| What is the immunofluorescence finding on Diabetic Glomerulosclerosis | show 🗑
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| Does Diabetic arteriosclerosis affect the afferent or efferent arterioles | show 🗑
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| show | Amyloidosis
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| show | monoclonal gammopathies associated with light chain deposition (lamda most common)
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| AA amyloid is associated with? | show 🗑
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| show | Rheumatoid arthritis, Chronic infections (TB), Some Neoplasms (Renal Cell Carcinoma and Hodgkin's)
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| show | Amyloid fibrils are non-branching with a uniform diameter of 8-12nM with a tangled appearance
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