MLT boards - Blood Bank (BOR)
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show | thrombocytopenia
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Following plasmapheresis, how long must a person wait before being eligible to donate a unit of Whole Blood ? | show 🗑
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show | 80
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Addition of what will enhance the shelf-life of whole blood? | show 🗑
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show | antibody screening by antiglobulin test
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show | ABO
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Under extreme emergency conditions when there is no time to determine ABO group for transfusion, the technologist should: | show 🗑
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An obstetrical patient has had 3 previous pregnancies. Her 1st baby was healthy, the 2nd was jaundiced at birth and required an exchange transfusion, while the 3rd was stillborn. Which os the following is the most likely cause? | show 🗑
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show | autosomal codominant
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show | -20 degrees C
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show | 22 degrees C
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show | -80 degrees C
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show | 4 degrees C
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show | reagent red blood cells
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show | mother has not been previously immunized to the D antigen
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show | d) confirmed positive test for HBsAg 10 yrs previous
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show | reciepient antibody directed against antigens on the donor red cells
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show | give a mixed field reaction with anti-A,B
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show | A3
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show | capable of causing hemolytic transfusion reactions
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A patient received 2 units of RBCs & had a delayed hemolytic Tx rxn. Pre-Tx records show a neg antibody screen. Repeat testing of the pre-Tx specimen detected an antibody at the antiglobulin phase. What is the most likely explanation for original resuts? | show 🗑
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show | agglutination with normal adult ABO-compatibility sera
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show | the agglutinates are mixed-field and refractile
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Mixed-field sgglutination athe the anti-human globulin phase of a crossmatch may be attributed to: | show 🗑
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show | determination of teh presence of spherocytes ans elevated numbers of nucleated red blood cells
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show | irradiated
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show | maternal serum
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When the main objective is an exchange transfusion is to remove the infant's antibody-sensitized RBCs and to control hyperbilirubinemia, the blood product of choice is ABO compatible: | show 🗑
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show | c) 41, 90/50, 99.4, 65, 65, M
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show | 3.0 x 10^11
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Following the 2nd spin in the preparation of Platelets, the platelets should be: | show 🗑
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What is the proper procedure for preparation of Platelets from Whole Blood? | show 🗑
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the purpose of a low-dose irradiation of blood components is to: | show 🗑
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Platelets prepared in a polyolefin type container, stored at 22-24 degrees C in a 50 mL a plasma, and gently agitated can be used for up to: | show 🗑
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The enzyme responsible for conferring H activity on the red cell membrane is alpha-: | show 🗑
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{refer to data on page 43} The ABO discrepancy seen above is most likely due to: | show 🗑
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show | anti-c & anti-E
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show | R1R1
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show | anti-K
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show | anti-Ch
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Useof EDTA plasma prevents activation of the classical complement pathway by: | show 🗑
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A Kleihauer-Betke stain of a postpartum blood film reveales 0.3% fetal cells. What is the estimated volume (mL) of the fetomaternal hemorrhage expressed as whole blood? | show 🗑
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The most effective component to treat a patient w/ fibrinoen deficiency is: | show 🗑
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An assay of plasma from a bag of cryoprecipitated AHF yields a concentration of 9 international units (IU) of Factor VIII per mL of cryoprecipitated AHF. If the volume is 9 mL, what is the Factor VIII content of the bag of IU? | show 🗑
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The approximate percentage of the original plasma content of Factor VIII recovered in cryoprecipitated AHF is: | show 🗑
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A newborn demonstrates petechiae, ecchymosis, and mucosal bleeding. The preferred blood component for theis infant would be: | show 🗑
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A 65-yr-old woman experienced shaking, chills, & fever of 103 degrees F approximately 40 min following the transfusion of a second unit of RBCs. The most likely explanation for the patient's symptoms is: | show 🗑
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An acid elution stain of a 1hr post delivery maternal blood, 2,000 cells were counted & 30 seemed to contain fetal hemoglobin. The medical center adds 1 vial of Rhogam to the dose when the est. volume of hemmorrhage exceeds 20 mL. Calculate the # of vials | show 🗑
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The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid: | show 🗑
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show | Factor IX
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show | b. spontaneous abortion at 2 months, 3 months ago
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What is correct storage temperature for Fresh Frozen Plasma? | show 🗑
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Whatis the possible genotype for an individual whose red cells give the reactions shown on page 47? | show 🗑
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What blood component contains the nost Factor VIII concentration relative to volume? | show 🗑
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show | Fresh Frozen Plasma
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show | cryoprecipitated AHF
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show | Prothronbin complex
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show | cirulatory overload
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show | hemolytic
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Hives and itching are symptoms of which transfusion reaction? | show 🗑
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Hemoglobinuria, hypotemsion, ans generalized bleeding are symptoms of what transfusion reaction? | show 🗑
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show | febrile
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show | I/i
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What is th most probable explanation for the results listed on pg 49? | show 🗑
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show | Rh
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show | Rh hemolytic disease of the newborn, infant has a false-negative Rh typing
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The use of Red Blood Cells, Deglycerolized would ve most beneficial when transfusing a patient: | show 🗑
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show | high concentration of glycerol (40%w/v)
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show | restore 2,3-DPG and ATP to normal levels
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A unit of RBCs is issued at 0900. At 0910 the unit is returned to the blood bank. The container has NOT been entered, but the unit has NOT been refrigerated during this time span. The best course of action for the tech is to: | show 🗑
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show | 12 months
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show | acceptable glycerol removal
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show | are agglutinated by most adult sera
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What situation could result in an ABO discrepancy that is caused by problems with the patient's red cells? | show 🗑
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What is characteristic of Tn polyagglutinable red cells? | show 🗑
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Mixed field agglutination encountered in ABO grouping would most likely be due to: | show 🗑
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The use of leukocyte-depleted RBCs and Platelet Concentrates is indicated for what patient group? | show 🗑
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Blood selected for exchange transfusion must: | show 🗑
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show | only in the newborns of group O mothers
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show | antenatal administration of RhIg at 28 weeks' gestation
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A blood component used in the trreatment of hemophilia A is: | show 🗑
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show | Cryoprecipitated AHF
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An adult patient who is activly bleeding has test results listed on pg 53. 6 units of RBC' are ordered STAT. The Blood Bank has the RBC units listed on pg 53. Which of the units should be crossmatched for this patient while more blood is being ordered? | show 🗑
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What blood component is most appropriate to transfuse to an 8-year-old male hemophiliac who is about to undergo minor surgery | show 🗑
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show | 5.5 x 10^10 platelets per unit in at least 75% of the units tested
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Based upon Kleinhauer-Betke test results. what formula is used to determine the volume of fetomaternal hemorrhage in mL of Whole Blood? | show 🗑
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According to the AABB standards, what is the minimum pH required for platelets? | show 🗑
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show | kept at room temperature
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A temperature rise of 1 degree C or more occuring in association with a transfusion is usually indicative of what transfusion reaction? | show 🗑
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show | bacterial contamination
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show | anaphylactic
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During initial investigation of a suspected hemolytic Tx rxn, it was observed the the posttransfusion serum was yellow in color and the direct antiglobulin test was negative. What is the next step in this investigation? | show 🗑
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A granulocyte transfusion is indicated if the patient has: | show 🗑
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Transfusion of what is needed to help correct hypofibrinogenemia due to DIC? | show 🗑
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According to AABB standards, Fresh Frozen Plasma must be infused within what period of time following thawing? | show 🗑
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In a quality assurance program, at least 75 of the bags of Cryoprecipitated AHF must contain a minimun of how many international units of Factor VIII? | show 🗑
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show | 1-6 degrees C
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show | 4 hours
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In the autoadsorption procedure for the removal of cold agglutinins from serum, pretreatment of the patient's red cells with what reagent is helpful? | show 🗑
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In an emergency situation, Rh-negative red cells are transfused into ans Rh-positive person of the genotype CDe/CDe. The first antibody MOST likely to develope is: | show 🗑
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A 10% red cell suspension in saline is used in a compatibility test. What would most likely occur? | show 🗑
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the most serious transfusion reactions are due to incompatibility in which of the following blood group systems? | show 🗑
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a 29-year-old male is hemorrhaging severly. He is AB NEG. 6 units of blood are required STAT. The blood bank has units of AB POS, A NEG, A POS, O NEG, which would be most preferable for crossmatch? | show 🗑
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show | perform antibody screening procedure at immediate spin using group O cells
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An antibody that causes in vitro hemolysis ans reacts with the red cells of three of ten crossmatched donor units is most likely: | show 🗑
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show | 1 to 5 days
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The most frequent transfusion-associated disease complication of blood transfusions is: | show 🗑
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show | O, Rh-negative Red Blood Cells
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The compatibility results on page 58 were obtained. The most probable explanation for these findings is that the: | show 🗑
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show | 1
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show | patient's serum was omitted from the original testing
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a Pt is group A2B POS & has an antiglobulin-reacting anti-A1 in his serum. He is bleeding profusely in the OR & group A2B RBC's are NOT available. What type of blood should be given as a 1st choice? | show 🗑
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What might cause a false-negative indirect antiglobulin test (IAT)? | show 🗑
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How many units of RBC's are required to raise the hematocrit of a 70-kg non-bleeding man from 24 to30%? | show 🗑
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show | an error in ABO grouping
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show | K
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show | addition of AHG is delayed for 40 minutes or more after washing the serum/cell mixture
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Which of the following antigens gives enhanced reactions with its corresponding antibody following treatment of the red cells with proteolytic enzymes? | show 🗑
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A request is received to crossmatch 5 units of RBCs on a man who is group AB, Rh-positive. The blood inventory is listed on page 60. Assuming all the blood crossmatched is compatible, the desirable sequence of blood units that can be issued for Tx is: | show 🗑
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The results of a Kleihauer-Betke stain indicate a fetomaternal hemmorrhage of 35 mL of Whole Blood. How many vials of Rh innune globulin would be required? | show 🗑
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What is the component of choice for treatment of von Willebrand's disease? | show 🗑
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What component id the best source of fibrinogen for transfusion to a patient with hypofibrinogenemia? | show 🗑
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show | Group A may be administered to both A and O reciepients
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What is an immediate non immunologic adverse effect of a transfusion? | show 🗑
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A 40-year-old man with autoimmune hemolytic anemia dude to anti-E has a hemoglobin level of 10.8gm/dL. This patient will most likely be treated with: | show 🗑
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On pg 62 are results of the history obtained from a prospective female blood donor. How many of the results will exclude this donor from giving blood for a routine transfusion? | show 🗑
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show | ABO incompatibility
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show | PVP iodine complex
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show | ingestion of fatty meal shortly before blood donation
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show | O, Rh-negative
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A patient who is group AB, Rh-negative needs 2 units of Fresh Frozen Plasma. Which units of pf plasma would be MOST acceptable for transfusion? | show 🗑
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Washed RBCs would be the product of choice for a patient with: | show 🗑
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show | 6 hours posttransfusion
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show | anti-D serum followed by washing and antiglobulin serum
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Refer to the data on page 64. These parents would most likely have a child with the genotype: | show 🗑
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show | Cryoprecipitated AHF
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show | R0R0
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Whole Blood for exchange transfusion of a newborn with hemolytic disease due to ABO incompatibility should be: | show 🗑
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show | autologous donations
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show | 2 are R1r, 2 are R1R1
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What unit should be selected for exchange transfusion if the newborn is group A, Rh-positive and the mother is group A, Rh-positive with anti-c? | show 🗑
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show | IgG and C3d
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show | detect preexisting antibodies on erythrocytes
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show | Karl Landsteiner
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show | 10,000
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show | 24 hours
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show | processed into components containing minimal plasma
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show | e
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show | Kidd
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Which of the following immunoglobulins is present in the highest concentration in normal human serum? IgM, IgG, IgA or IgE | show 🗑
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A mother is Group A, with anti-D in her serum. What is the preferred blood product if an intrauterine transfusion is indicated? | show 🗑
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show | a visual inspection for free plasma hemoglobin
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Even in the absence of prior transfusion or, individuals with the Bombay pheno-type (Oh) will always have naturally occurring: | show 🗑
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HLA antibodies are: | show 🗑
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show | the coordination of cellular and humoral immunity
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show | Red Blood Cells
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Which of the following antigens in MOST likey to be involved in hemolytic disease of the newborn? Lea, P1, M or Kell | show 🗑
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Fresh frozen Plasma should be transfused within: | show 🗑
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Cryoprecipitated AHF is indicated for: | show 🗑
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An important determinant of platelet viability following storage is: | show 🗑
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According to AABB standards, Platelets must be__________________if stored at room temperature. | show 🗑
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Platelet transfusions are of most value in treating: | show 🗑
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An unexplained fall in hemoglobin and mild jaundice is a patient transfused with RBCs 1 week ago would most likely indicate: | show 🗑
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Fresh Frozen Plasma from a group A, Rh-positive donor may be safely transfused toa a patient who is group: | show 🗑
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the drug cephalosporin can cause a positive direct antiglobulin test by what mechanism? | show 🗑
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Which would most likely be responsible for an incompatible major crossmatch? recipient's RBCs posses a low-frequency antigen, anti-K antibody in donor serum, recipient's RBCs are polyagglutinable, donor RBCs have a positive DAT | show 🗑
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Rh immune globulin administration would NOT be indicated in a Rh-negative woman who has a: 1st trimester abortion, husband who is Rh-positive, anti-D titer of 1:4096, or positive direct Coomb's test | show 🗑
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A fetomaternal hemprrhage of 35 mL of fetal Rh-positive packed RBC's has been dected in an Rh-negative woman. How many vials of Rh immune globulin should be given? | show 🗑
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what information is essential on the label of recipient blood samples drawn for compatibility testing? | show 🗑
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Which of the following red cell antigens are found on glycophorin-A? M and N, Lea ad Leb, S and s, P and P1 and Pk | show 🗑
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show | syphilis
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irradiation of a unit of red Blood Cells is done to prevent the replication of donor: | show 🗑
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AHG (coombs) control cells are coated only with: | show 🗑
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During the issue of an autologous unit of Whole Blood, the supernatant plasma is observed to be dark red in color. what would be the best course of action? | show 🗑
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show | rr
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A first-time blood donor is noticed to experience rapid breathing and involuntary twitching of his fingers shortly after starting phlebotomy. The phlebotomist should: | show 🗑
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show | accurately identify the donor unit and intended reciepient
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show | Black
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the Kell (K1) antigen is strongly: | show 🗑
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show | anti-Lua
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show | anti-Yta
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A donor is tested with Rh antisera, with the following results: anti-D + anti-C + anti-E 0 anti-c + anti-e + Rh control 0 What is the most probable Rh genotype? | show 🗑
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show | 'The original reaction was due to true agglutination.
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What is a frequent characteristic of anti-i? | show 🗑
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the test currently used to detect donors who are infected with the AIDS virus is: | show 🗑
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show | ABO and Rh typing only
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show | 150 x 10^3/uL
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a patient admitted to the trauma unit requires emergency release of Fresh Frozen Plasma (FFP). His blood donor card states that he is group AB, Rh-positive. What blood group of FFP should be issued? | show 🗑
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Refer to the data on page 74. Which clinical condition is consistant with the lab results shown? | show 🗑
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the mechanism that best explains hemolytic anemia due to penicillin is; | show 🗑
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Laboratory studies of maternal and cord blood yield the results listed on page 74. If exchange transfusion is necessary, the best choice of blood is: | show 🗑
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show | maternal serum
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show | hypogammaglobulinemia due to advanced patient age
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show | recipient alloantibody
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Refer to the data on page 75. Consider the following ABO typing results: Additional testing was performed using serum: What should be done next? | show 🗑
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For what transfusion canidates would CMV-seronegative blood be MOST likely indicated? | show 🗑
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Posttransfusion purpura is caused by: | show 🗑
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show | IgA deficiency
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show | the indirect antiglobulin test
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show | c. 22-year-old college student who has a temperature of 99.2 degrees F and states that he feels well but is nervous about donating
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show | severely thrombocytopenic patients, known to be refractory to random donor platelets
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Why are donors deferred for 6 months following receipt of blood products? | show 🗑
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A 37-year-old female w/ SLE is admitted w/ anemia. Blood samples are received w/ a crosmatch request for 4 units or RBCs. the patient is group B, Rh-negative. Using the testing results on page 77, what is the most likely cause of the results? | show 🗑
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A 42-year-old female is undergoing surgery tomorrow 7 her physician requests that 4 units of RBCs be crossmatched. See page 77 for results. What is the most likely cause of the incompatibility of donor 1? | show 🗑
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show | weak subgroup of A with anti-A1
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A 14-year-old male trauma victim is in need of 3 units of RBDs. Refer to page 78 for the results obtained during pretransfusion testing. What is the FIRST step in resolving this problem? | show 🗑
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show | anti-HIV-1
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A commonly used screening method for anti-HIV-1 detection is: | show 🗑
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show | Fy(a-b-)
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An individual's RBCs give the reactions listed on page 79 with Rh antisera. The most probable genotype of this individual is: | show 🗑
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show | Ax- with an anti-A1 antibody
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show | severe neutropenia with an infection nonresponsive to antibody therapy
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show | irradiated
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show | Dolichos biflorus
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show | Fresh Frozen Plasma
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Anti-I usually results in a positive direct antiglobulin test (DAT) because of: | show 🗑
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show | synthesis of antibody
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Plastic bog overwraps are recommended when thawing units of FFP in 37 degree C water baths because they prevent: | show 🗑
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show | 35 days
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Refer to the chart on page 81. What is the best interpretation for the laboratory data given in the chart? | show 🗑
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show | defer the donor permanently
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show | jaundice
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show | multiple myeloma
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show | quarantine for Gram Stain and culture
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show | a directed donation given by a mother for her son
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show | notify the collecting facility
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show | recheck the antisera with positive and negative controls
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Leukocyte-reduced Red Blood Cells are ordered for a newly diagnosed bone marrow candidate. What is the best way to prepare this product? | show 🗑
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show | every 4 hours
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show | direct antiglobulin
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show | complement
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show | 12.5
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The purpose of testing with anti-A,B is to detect: | show 🗑
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show | the father is heterozygous Rh-positive
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In performing an antibody screening test and/or compatibility test, the use of a patient's specimen collected in an EDTA tube will: | show 🗑
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What represents an acceptably identified patient for sample collection and transfusion? | show 🗑
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Rh-immune globulin is requested for an Rh-negative mother who has the following results: Mothers postpartum sample D=0, D control=0, Du=1+mixed field, Du control =0. What is the most likely explanation? | show 🗑
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Samples from the patient on page 85 were received on 2 consecutive days. Test results are listed on page 85. How should the request for crossmatch be handled? | show 🗑
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The following results are seen on a maternal postpartum sample: Aother's cells Rh=0, Rh control=0, Du =+mixed field, Du control=0. The most appropriate course of actionis to: | show 🗑
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show | the sample is Rh-positive
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Review the schematic diagram on page 86. The next step would be: | show 🗑
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the most common cause of posttransfusion hepatitis can be detected in donors by testing for: | show 🗑
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A unit os packed cells is split into 2 aliquots under closed sterile conditions at 8 AM. The expitation time for each aliquot is now: | show 🗑
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A group-B, Rh-negative patient has a positive DAT. What situation would occur? | show 🗑
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show | cryoprecipitated AHF
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A group B, Rh-negative patient is shock from acute blood loss would benefit most from a transfusion: | show 🗑
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show | 11 g/dL
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show | units of group O, Rh-negative Red Blood Cells
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