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Essentials of Radiation Biology and Protection 2nd Edition Chapter 4

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Radiation sickness, known as _____, is a serious illness that occurs when the entire body receives a high dose of radiation, usually over a short period of time.   Acute Radiation Syndrome  
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in order for the total body radiation syndrome to be applicable, radiation exposure must happen under the following conditions   An organ must have been exposed acutely, there must be exposure of the total body area, External penetrating sources  
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The lethal dose required to kill 50% of the population in 30 days is the definition of:   LD 50/30  
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The acute radiation syndrome includes the following:   Bone Marrow Syndrome, Gastrointestinal Syndrome, Centeral Nervous Syndrome  
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Response stages with the acute radiation syndrome include the following:   Prodromal Stage, Latent Stage, Manifest Stage, Recovery Stage  
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For the acute radiation syndrome, in the 100-1,000 R range, death is mostly the result of damage to the:   Hemopoietic  
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For the acute radiation syndrome, in the 600-10,000 R range, death is mostly the result of damage to the:   Grastrointestinal  
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For the acute radiation syndrome, at dose greater than 10,000 R, death is mostly the result of damage to the:   Central Nervous  
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In the _____stage, the person experiences nausea, vomiting and diarrhea.   Prodomal  
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In the _____ stage the person appears to be symptom-free.   latent  
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In the _____ stage, the person becomes noticeably ill and shows signs and symptoms of the specific syndrome reflecting the organ system which is damaged.   manifest  
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The shrinking of tissues or organs due to irradiation is termed:   Atrophy  
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Redness and swelling at the site of radiation exposure is termed:   Inflammation  
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The peeling off of skin caused by irradiation is termed:   Desquamation  
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Abnormal redness of skin due to irradiation is termed:   Erythema  
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The correct order of layers of skin, from outermost to innermost:   Epidermis, Dermis, Subcutaneous  
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The skin erythema dose necessary to affect 50% of the people irradiated is termed:   SED50  
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The SED50 is estimated to be approximately:   600  
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Epilation or alopecia are terms for:   Hair Loss  
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The formation of cataracts caused by radiation is termed:   Radiation Cataractogenesis  
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Radiation induced cataracts follow a threshold, nonlinear dose-response curve with the threshold thought to be approximately:   200  
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Radiation induced cataracts have an average latent period of approximately:   15  
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Doses as low as _____ have caused observable responses to human gonads.   10  
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The reproductive cells of the female are termed:   Oogonia  
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The reproductive cells of the male are termed:   Spermatogonia  
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Depletion of mature sperm in the male due to irradiation is termed:   Maturation depletion  
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An acute dose to male and female gonads of approximately _____ will cause permanent sterility.   500-600  
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Regarding the bone marrow cells, what is the correct order from least sensitive to most sensitive?   Megakaryocytes, Myelocytes, Erythroblasts  
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Following radiation exposure to the bone marrow, what are the first cells to be reduced?   Red Blood Cells  
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The main effect on the male gonads is damage to and reduction in the number of the:   Spermatogonia  
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The main effect on the female gonads is damage to the:   Mature Follicles  
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It takes a minimum whole-body dose of approximately ____ to cause hematologic depression.   25  
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Structural changes to the chromosome that occur after irradiation are termed:   Aberrations, Lesions, Anomalies  
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Radiation-induced chromosomal damage that occurs before DNA synthesis is known as:   Chromosomal Aberration  
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Radiation-induced chromosomal damage that occurs after DNA synthesis is known as:   Chromatid Aberration  
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What is a chromosome map used for cytogenetic analysis of chromosomes?   Karyotype  
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Which acute radiation syndrome has an average survival time that is independent of dose?   Gastrointestional  
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What would be considered an early response to irradiation?   Breast Cancer  
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What are some acute local tissue effects of radiation exposure?   Cataracts  
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Death from a single dose of whole body irradiation primarily involves damage to the:   Bone Marrow  
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What is the principal response of the blood caused by radiation exposure?   Decrease in cell number  
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