pharm ch 11, kilgore lvl1
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| show | drugs that depress the central nervous system (CNS)
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| effects of anesthetics | show 🗑
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| show | a state of depressed CNS activity
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| show | type of anesthetics that affects entire body (puts you to sleep)
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| show | type of anesthetic that only affects the part of body being worked on
-general conscience
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| show | combination of anesthetic drugs
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| effects of general anesthetics | show 🗑
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| show | volatile liquids or gases that are vaporized in O2 and inhaled
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| inhaled gas | show 🗑
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| show | -enfulrane (Ethrane)
-halothane (Fluothane)
-isoflurane (Forane)
-methoxyflurane (Penthrane)
-others
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| show | administered intravenously
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| effects of injectable anesthetics | show 🗑
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| Type of injectable anesthetics | show 🗑
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| sedative-hypnotics | show 🗑
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| show | used as adjuctive drugs
-morphine, fentanyl, sufentanil
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| show | used as adjunctive drug to relax skeletal muscles
depolarizing and nondepolarizing drugs
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| show | type of NMBAs
-succinylcholine
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| show | type of NMBAs
-pancuronium, d-tubocurarine, vecuronium
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| show | used as adjunctive drug
-atropine, glycopyrrolate, scopolamine
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| show | anesthetics have high lipid soluability and therefore have a high potency
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| show | -orderly and systematic reduction of sensory and motor CNS functions
=progressive depression of cerebral and spinal cord functions
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| show | -unconsciousness
-skeletal muscular relaxation
-visceral smooth muscle relation
-rapid onset and quickly metabolized
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| Adverse effects (AEs) of anesthetics | show 🗑
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| malignant hyperthermia- idiopathic | show 🗑
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| Local anesthetics/regional anesthetics | show 🗑
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| show | applied directly to skin or mucous membranes
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| show | injected IV or into the CNS by various spinal injection techniques (Epidural)
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| show | type of local anesthesia
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| Intrathecal | show 🗑
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| show | type of local anesthetic
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| show | type of local anesthetic injected diretly into the nerve area (Dental work)
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| show | parenteral anesthetic drug that is a blocker and is injected
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| steps to paralysis via anesthetics | show 🗑
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| show | what local anesthetics are used for
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| show | types/routes of local anesthetics given
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| show | used in/for:
-minor surgical and dental proceduress
-injection ID, subcut, or submucosally across the path of nerves supplying the target area
-may be given in a circular pattern around the operative area
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| Nerve block anesthesia | show 🗑
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| Major AEs of infiltration and Nerve block anesthesia | show 🗑
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| Uses of NMBAs | show 🗑
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| Special considerations for NMBAs when used during surgery | show 🗑
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| types of NMBAs-nondepolarizing drugs | show 🗑
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| Succinylcholine | show 🗑
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| show | -similar to ACh in causing depolarization
-slower metabolism than ACH, repolarization cannot occur while present
-causes flaccid muscle paralysis
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| show | -prevent ACh from acting at neuromuscular junctions
-muscle fibers are not stimulated bc nerve cell membrane is not depolarized
-skeletal muscle contraction does not occur
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| sequential effects of NMBAs | show 🗑
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| show | -maintaining controlled ventilation during surgical procedures
-endotracheal intubation (short acting)
-reduction of muscle contraction in target area
-diagnostic drugs for myasthenia gravis
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| AEs of NMBAs | show 🗑
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| show | -Cardiovascular collapse
-conscious sedation, moderate sedation, procedural sedation, a semi-conscious effect
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| Moderate sedation (conscious sedation, procedural sedation) | show 🗑
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| show | -vital signs
-baseline labwork, ECG
-Pulse oximeter (PO2)
-ABCs
-all body systems
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| what to watch for during recovery | show 🗑
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| propofol | show 🗑
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| succinylcholine | show 🗑
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| show | -intermediate-acting NONdepolarizing NMBA
-adjunct to gen. anesthesia
-most useful in procedures requiring mechanical ventilation
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