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WillWallace Fomulas & Norms

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Question
Answer
show PaO2/PAO2 norm is 90%, >35%=weaning, reflects efficiency of oxygenation as a percentage, <74%=shunt, V/Q mismatch or diffusion defect  
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show A-a gradient, norm 5-10 mmHg on .21, 30-60 on 100%, >350=mech support, <350 weaning. Represents potential to Oxygenate vs. the amount of O2 in the artery. Every 50mmHg is approx. 2 percent shunt above norm of 2-5%  
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Alveolar Air Equation   show
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show norm 120/80 (90-140/60-90), <90/60 or >180/110 is inconsistent with weaning  
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show norm 16-20 vol% (Hbx1.34)SaO2 + (PaO2x.003) total amount of O2 carried in 100ml of blood, combined content of O2 carried on Hb and dissolved in plasma, (can be reduced by <Hb, anemia or <CO)  
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show Content of pulm capillary blood oxygen at 100% FIO2, (Hbx1.34)1 + (PAO2x.003) used in shunt equation  
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show dynamic compliance, aka CLdyn, norm is 0.03-0.04L/cmH2O (30-40mL/cmH20), calc is Vt(L)/(PIP-PEEP) Changes in CD indicate changes in CL or elastance. Up with decreased elasticity (emphysema, down with with stiff (ARDS).  
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CI   show
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Cs (CVAE)   show
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show Tube compliance aka compressible volume, volume lost to pt circuit, approx 3ml/cmH20 x PIP, deduct from VT to find actual delivered tidal volume. VT-(PIP x 3) equals actual VT.  
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show (Hb x 1.34)SvO2 + (PvO2 x .003) norm is 15 vol%, represents the value of O2 in blood returning to the right side of the heart after tissues have oxygenated.  
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show central venous pressure, norm 2-6 mmHg, 2-6 weaning  
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Deadspace   show
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show O2 Delivery, (CaO2 x CO) x 10, norm is 1000mL/O2/min  
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show <40-50% weaning  
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show (VT/IT) x 60 or VE x (I+E)  
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Flow required for a 1 second I-time and a VT of 750cc?   show
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Hb   show
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HCO3   show
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show 40-50%  
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show norm 60-80, 60-120 weaning  
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I:E ratios/%   show
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show 105+5/lb over 60"  
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IBW M   show
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I-time   show
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Low press on vent   show
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show TIIVR+TIVER, FRC=TIIVR=TLC, IRV, IC, VC, RV, + TIVER, FRC=TLC, IRV, VT, ERV, RV, FRC  
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show Mean arterial pressure, norm 90 (80-100), 70-130 weaning  
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MIP/NIF   show
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show 35-45 torr, >55 indicates support, <50 weaning  
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show <PIP, <RR, >PEEP  
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show CO2 desired, CO2 is adjusted by changing Resp rate so (VExCO2)/CO2d=VEd or (RRset x CO2)/CO2d=RRd, always round down and go slightly acidic as tissue will oxygenate better.  
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PaCO2-to decrease with pt on mech vent   show
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show 80-100 torr, >60 mmHg on <60% weaning  
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PaO2 <80 on FIO2 <60   show
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PaO2 <80 on FIO2 >60   show
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show PaO2 (desired) x FIO2 (current)/PaO2 (current)=FIO2 required to bring PaO2 to desired level. Example of pt on 40% FIO2, PaO2 of 53 and wanting PaO2 of 80, calc is (80x.4)/53 equals .60, so increase FIO2 to 60%  
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PaO2/FIO2   show
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PaO2-to decrease while pt on mech vent   show
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show >PIP, >RR, >PEEP, or >FIO2  
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PAP   show
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PCWP   show
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PEEP   show
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PH   show
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PIP   show
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show 40 torr  
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QS/QT   show
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QT   show
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show Airway Resistance norm is 5-12cmH2O/L/Sec for intubated pt, (PIP-Pplat)/(flow in min/60 sec). Increase in RAW reflects an issue with airways, bronchospasm, secretions, edema etc.  
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Refractory hypoxemia   show
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RR   show
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RSBI   show
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RV   show
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SaO2   show
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Shunt   show
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SvO2   show
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show Time constant, (Raw x CS)e, where e represents volume exhaled as a percent, 1 is 63%, 2 is 86%, 3 is 95% and 5 is 100% exhaled. TC <3 leads to air trapping.  
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TCT   show
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show total lung capacity 6L  
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VA   show
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show Vital capacity, 65-75 mL/kg, <10mL/kg indicates support, >15 mL/kg for weaning  
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show Deadspace volume, VD=(VT-VA), norm is 33% of VE, 1 mL/lb IBW or 2.2mL/kg (approx 150 ml)  
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VD/VT Ratio   show
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VE   show
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VEspont   show
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VO2   show
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VTspont   show
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VT   show
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