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Biochem Final, Mizzou, Spring 2015

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Term
Definition
circular   show
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show where the DNA or "genome" is located eukaryotic cells  
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linear   show
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show genes are composed of ____  
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show have 20-30,000 genes  
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nucleotides   show
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show consist of a nitrogen base, a monosaccharide, & at least one phosphate  
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show sugar is a ribose, contains an OH group on the 2' C  
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show sugar is a deoxyribose, contains an H group on the 2' C  
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show a nitrogen base & a ribose sugar  
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show a nucleoside (base and ribose) with a phosphate group  
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show this structure of nucleic acids is the order of the bases  
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show this structure of nucleic acids is the 3-D conformation of the polynucleotide backbone  
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show this structure of nucleic acids is the supercoiling  
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show this structure of nucleic acids is the DNA/ protein interactions  
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show nucleotides are linked 5' to 3' by _________ bonds (primary structure)  
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show the sugar-phosphate backbone is _______ (primary structure)  
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variable   show
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show the ordered arrangement of nucleic acid strands  
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show 2 anti-parallel DNA strands coiled around the same axis (spiral staircase) this is the secondary structure  
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show DNA strands are anti-parallel and overall DNA is _____ charged (acidic)  
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hydrogen   show
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show A-T has ____ hydrogen bonds  
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three   show
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show B-DNA is a *right-handed* helix (point thumb up, DNA winds ____ in direction fingers are pointing)  
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32   show
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supercoiling   show
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show enzymes that control the supercoiled state of DNA are ________  
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topoisomerase 1   show
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show cuts BOTH strands, passes some of the remaining DNA helix between the cut strands, and reseals; gets rid of 2 coils at a time  
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show supercoiling of eukaryotic DNA occurs through complexes with proteins called _______  
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show histones are _____ charged proteins; rich in the basic amino acids lysine and arginine  
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chromatin   show
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nucleosome   show
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histone proteins   show
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show is the increase of absorbance (optical density) of a material. The most famous example is that of DNA that occurs when the DNA duplex is denatured  
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show the pyrimidine nitrogen bases in RNA are ____ and cytosine  
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tRNA   show
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show FOUND IN RIBOSOMES, the site of protein synthesis  
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show directs amino acid sequence of proteins; contains the genetic information from DNA (genes); is translated into a polypeptide sequence (protein or an amino acid polymer)  
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