Goljan HY CNS
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show | choroid plexus in ventricles; enters subarachnoid space; removed by arachnoid granulations
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show | less protein and glucose than serum; scant number of cells; ↑ chloride
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Xanthochromia | show 🗑
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Papilledema of optic nerve | show 🗑
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show | intracranial hypertension; medial portion temporal lobe through tentorium cerebelli
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S/S | show 🗑
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show | compression of parasympathetic system
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show | intracranial hypertension
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show | ↑ CSF volume with distention of ventricles
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Non-communicating | show 🗑
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show | choroid plexus papilloma; scarring of arachnoid granulations
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Adults with hydrocephalus | show 🗑
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Open neural tube defects | show 🗑
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Spina bifida occulta | show 🗑
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Meningocele | show 🗑
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Meningomyelocele | show 🗑
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Arnold Chiari syndrome | show 🗑
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show | hydrocephalus, syringomyelia, meningomyelocele
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Dandy Walker syndrome | show 🗑
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show | enlarged cervical cord; fluid filled cyst in cervical spinal cord
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show | loss pain/temperature upper extremities (spinothalamic); motor loss in hands (anterior horn cells)
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Tuberous sclerosis | show 🗑
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Tuberous sclerosis | show 🗑
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Neurofibromatosis | show 🗑
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Associations | show 🗑
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Meningitis | show 🗑
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CSF findings viral meningitis | show 🗑
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show | ↑ CSF protein, ↓ CSF glucose, ↑ neutrophils
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Encephalitis | show 🗑
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show | MCC viral meningitis
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show | hemorrhagic necrosis in temporal lobes
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show | skunk and bat common vectors; Negri bodies in neurons; hydrophobia; flaccid paralysis
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CMV | show 🗑
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Polio virus | show 🗑
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Subacute sclerosing panencephalitis | show 🗑
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show | slow virus disease due to JC virus; common in AIDS
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show | prions; spongiform encephalopathy
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show | contact with human brain or contaminated beef (bovine disease)
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Meningitis newborn | show 🗑
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Listeria monocytogenes | show 🗑
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Neisseria meningitidis | show 🗑
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show | MCC meningitis >18-yrs-old
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show | complication primary TB; base of brain meningitis with vasculitis
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Neurosyphilis | show 🗑
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show | vasculitis causing strokes
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show | syphilis with dementia and brain atrophy
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show | posterior root ganglia/posterior column; ataxia; absent deep tendon reflexes; Argyll-Robertson pupil
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show | pupil accommodates but does not react to direct light; THINK
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Cryptococcus neoformans | show 🗑
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show | frontal lobe abscess in diabetic ketoacidosis
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Toxoplasma gondii | show 🗑
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show | calcification basal ganglia; blindness; mental retardation
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Naegleria and Acanthamoeba | show 🗑
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Taenia solium | show 🗑
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Cysticercosis | show 🗑
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show | contusions at site of injury
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show | contusion on opposite side of injury; frontal and temporal lobes
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Epidural hematoma | show 🗑
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show | tear bridging veins; venous blood clot; fluctuating levels of consciousness
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Hypoxic injury | show 🗑
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show | liquefactive necrosis at watershed areas in cortex
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Atherosclerotic stroke | show 🗑
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Causes atherosclerotic stroke | show 🗑
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MCA stroke | show 🗑
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show | loss vision described as curtain going down and then up
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Cause | show 🗑
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show | vertigo, ataxia, ipsilateral sensory loss face/contralateral hemiparesis/sensory
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show | hemorrhagic infarction extending to periphery cerebral cortex due to embolization
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show | complication hypertension
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show | rupture of aneurysm of lenticulostriate vessels
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show | basal ganglia MC site
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show | rupture of congenital berry aneurysm; severe occipital headache
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Lacunar stroke | show 🗑
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show | posterior limb internal capsule
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Pure sensory stroke | show 🗑
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Multiple sclerosis | show 🗑
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show | scanning speech, intention tremor, nystagmus, paresthesias, weakness
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show | multiple sclerosis; demyelination MLF
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CSF with oligoclonal bands | show 🗑
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show | rapid intravenous correction of hyponatremia in alcoholic
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Alzheimer’s disease | show 🗑
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Alzheimer’s disease | show 🗑
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show | ↑ density of neurofibrillary tangles and senile plaques
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show | develop Alzheimer’s disease at early age; 3 functioning chromosome 21s
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Apo E gene allele ε4 | show 🗑
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show | depigmentation substantia nigra neurons; Lewy bodies; ↓ dopamine
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show | extrapyramidal (muscle rigidity), resting tremor, festinating (shuffling) gait
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show | CO poisoning, Wilson’s, MPTP (meperidine derivative), drugs
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Huntington’s disease | show 🗑
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show | movement disorder; dementia
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show | degeneration of lower/upper motor neurons; no sensory changes
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show | childhood type of ALS
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show | AR; excess copper; cystic degeneration of putamen/globus pallidus
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show | posterior column (↓ proprioception, vibration); lateral corticospinal tract (UMN)
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Alcohol | show 🗑
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show | thiamine deficiency; IV with glucose can prompt acute attack
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Wernicke encephalopathy | show 🗑
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show | confusion, ataxia, nystagmus, ophthalmoplegia
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Korsakoff's psychosis | show 🗑
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Acute intermittent porphyria (AIP) | show 🗑
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show | drug induced (alcohol, barbiturates); abdominal pain (“bellyful of scars”); dementia
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show | urine in AIP colorless; turns port wine color with exposure to light (porphobilin)
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Rx | show 🗑
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Adult brain tumors | show 🗑
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Childhood brain tumors | show 🗑
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Adult brain tumors (descending order) | show 🗑
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show | high grade astrocytoma; hemorrhage and necrosis; may cross corpus callosum
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Meningioma | show 🗑
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show | schwannoma of the VIIIth nerve; tinnitus; sensorineural hearing loss; neurofibromatosis
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show | astrocytoma cerebellum (MC), medulloblastoma
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Astrocytoma | show 🗑
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show | malignant tumor cerebellum; invades fourth ventricle
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show | arises in 4th ventricle in children and cauda equina in adults
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Oligodendroglioma | show 🗑
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CNS lymphomas | show 🗑
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Metastasis | show 🗑
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Schwannoma | show 🗑
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AIDS dementia | show 🗑
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CMV retinitis | show 🗑
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Peripheral neuropathy | show 🗑
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Peripheral neuropathy | show 🗑
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show | MCC autoimmune demyelination of peripheral and spinal nerves
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show | M. pneumoniae, influenza vaccine, Campylobacter jejuni
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S/S | show 🗑
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show | AD; common peroneal nerve palsy; inverted bottle appearance
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Idiopathic Bell’s palsy | show 🗑
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show | facial nerve MC cranial nerve involved; bilateral Bell’s palsy
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show | Staphylococcus aureus
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Viral conjunctivitis | show 🗑
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show | amaurosis fugax, central retinal artery or vein occlusion
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Uveitis | show 🗑
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Optic neuritis | show 🗑
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Glaucoma | show 🗑
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show | blindness; pale disc; glaucoma, optic neuritis
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show | MCC permanent visual loss in elderly
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Meniere’s disease | show 🗑
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show | MCC sensorineural hearing loss in elderly
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Otosclerosis | show 🗑
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Impacted wax in outer ear canal | show 🗑
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show | conduction loss left ear
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show | sensorineural hearing loss right ear
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Otitis media | show 🗑
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show | Pseudomonas aeruginosa
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