DCPA Antibiotics
Help!
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| show | Presence of microbe in a host does not cause a specific immune reaction or infection (Do NOT Tx w/ Abx)
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| Empiric Therapy | show 🗑
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| show | Abx choise based on identified pathogen & susceptibilty patterns
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| De-escalation | show 🗑
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| Collateral Damage | show 🗑
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| Minimum Inhibitory Concentration (MIC) | show 🗑
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| show | Compilation of data for bacteria vs. abx
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| Gram (+) Cocci bacteria | show 🗑
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| show | Associated with "hardware"
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| show | UTI, appendicitis
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| show | Bowel lesion = spread of infection
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| show | Abcess Formers
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| Gram (+) Bacilli Bacteria | show 🗑
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| show | Meningitis (Can't eat cheese in 2nd/3rd trimester)
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| Gram (-) Cocci Bacteria | show 🗑
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| show | Vibrio cholerae, Campylobacter jejuni, H. Pylori, Pseudomonas Aeruginosa, Salmonella, H. Influenza, Brucella, Francisella Tularensis (Tularemia), Pasturella Multocida, Legionella Pneumophilia, Bartonella, Shigella, Enterobacter (E. Coli, etc.)
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| show | Bites (Mouths) or Cats & dogs
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| show | Cat scratch
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| Anaerobes | show 🗑
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| Clostridium Perfringens Infection | show 🗑
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| show | Penicillin, Cephalosporin, Carbapenems, Aztreonam
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| Beta-Lactums MOA | show 🗑
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| show | Interferes with cell wall synthesis
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| Fluoroquinolones MOA | show 🗑
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| show | Interferes with DNA replication, transcription
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| Aminoglycosides MOA | show 🗑
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| Macrolides MOA | show 🗑
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| show | Binds to 30s/50s Ribosomal Subunit
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| show | Binds to 30s/50s Ribosomal Subunit
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| Tetracyclines MOA | show 🗑
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| show | Binds to 30s/50s Ribosomal Subunit
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| Broad Spectrum Drugs | show 🗑
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| show | Vancomycin
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| Narrow Spectrum Gram(-) Drugs | show 🗑
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| show | Metronidazole (Flagyl)
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| Pharmacokinetics | show 🗑
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| Pharmodynamics | show 🗑
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| show | % of oral dose available compared to IV form (100%)
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| Clearance | show 🗑
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| show | Relates the amount of drug in the body to the serum drug concentration (Dependent on BMI)
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| show | After 3 half lives
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| show | Delay before organisms recover & begin growing despite decrease concentration of drug
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| Four Primary Machanisms of Resistance. | show 🗑
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| show | DONT under dose/increase duration = resistance
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| show | Beta Lactams, Cephalosporins, quinolones, aminoglycosides
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| Bacterostatic Drugs | show 🗑
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| show | Nephrotoxic (reversible) & Toxic to the Ear (irreversible)
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| Drugs that penatrate the BBB to the CSF | show 🗑
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| show | Bone, synovial fluid, prostate, Abscesses, Peritoneal Fluid
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| show | Drug of Choice
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| show | Indications
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| show | Adverse Reactions
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| show | Warnings & Precautions
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| SSSI | show 🗑
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| show | (IgE) Hives (Uticaria). Respiratory Difficulty (Bronchospasm). Swelling. Occurs within the first 72 hours.
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| show | Penicillin
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| Penicillin ADR | show 🗑
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| Penicillin half life | show 🗑
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| show | Natural, Penicillinase-resistant, Aminopenicillins, Extrended-spectrum ureidopenicillins, B-lactam/B-lactamase Inhibitors
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| show | Penicillin G (IV/IM) & Penicillin V (PO)
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| Natural Penicillin effective against... | show 🗑
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| Natural Penicillin DOC | show 🗑
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| Natural Penicillin R | show 🗑
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| show | C
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| Natural Penicillin ADR | show 🗑
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| show | Oxacillin/Nafcillin (IV) & Dicloxacillin (PO-empty stomach)
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| Penicillinase-resistant penicillins effective against... | show 🗑
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| Penicillinase-resistant penicillins ADR | show 🗑
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| show | Ampicillin (IV/PO), Amoxicillin (PO)
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| show | Enterococci, E.coli, H. influenza, Proteus, Klebsiella
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| show | Renal Insufficiency & Cephalosporin allergy
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| show | Rash & GI upset
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| show | Pipercillin (IV) usually used in combination!
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| show | Anaerobes, enterobactericacae & pseudomonas
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| Extended-spectrum ureidopenicillins W/P | show 🗑
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| Extended-spectrum ureidopenicillins ADRs | show 🗑
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| B-lactamase inhibitor drugs | show 🗑
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| show | Ampicillin & sulbactam
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| show | Pipercillin & tazobactam
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| show | Amoxicillin & Clavulanate
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| show | Diarrhea (increased with clavulanate)
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| Penicillin Class drug interactions | show 🗑
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| Penicillin Class ADRs | show 🗑
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| Cephalosporins types | show 🗑
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| Cephalosporins pregnancy categroy | show 🗑
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| Cephalosporins ADRs | show 🗑
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| 1st generation cephalosporins drugs & forms | show 🗑
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| show | Ancef
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| Cephalexin | show 🗑
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| 1st generation cephalosporins coverage | show 🗑
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| show | surgical prophylaxis, SSSIs & UTI
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| show | Less gram + & more gram -
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| 2nd generation cephalosporins drugs | show 🗑
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| show | strep, haemophilus, E. coli, Proteus, Klebsiella
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| Cefuroxime (Ceftin)uses | show 🗑
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| Cefuroxime | show 🗑
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| show | Cefotan
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| Cefotetan (Cefotan) covers | show 🗑
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| Cefotetan (Cefotan) uses | show 🗑
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| show | weak gram + & good gram -
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| show | Ceftriaxone (Rocephin) - IV. Ceftazadime (Fortaz - IV. Cefpodoxime (Vantin) - PO. Cefixime (Suprax) - PO
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| show | Rocephin
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| Ceftriaxone (Rocephin) ADRs | show 🗑
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| show | Severe gram (-) infection & Meningitis
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| Ceftazadime | show 🗑
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| Ceftazadime (Fortaz) coverage | show 🗑
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| show | Vantin
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| Cefixime | show 🗑
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| show | URIs & RTIs
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| 4th Generation Cephalosporin drug & form | show 🗑
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| show | Pseudomonas, gram (-) rods (enterobacter, serratia & citrobacter).
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| show | Febrile neutropenia, hospital acquired pneumonia, serious gram (-) infections.
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| show | Imipenem/cilastatin (Primaxin) - IV. Meropenem (IV). Ertapenem (Invanz)- IV.
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| show | imipenem/cilastatin
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| show | gram +'s including MSSA, grams -'s & anaerobes.
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| Primaxin (Imipenem/cilastatin) uses | show 🗑
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| Primaxin (Imipenem/cilastatin) ADR | show 🗑
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| show | Hx of seizures
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| Primaxin (Imipenem/cilastatin) pregnancy category | show 🗑
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| show | Less seizures & N/V
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| show | B
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| show | Staph & strep
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| Ertapenem | show 🗑
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| Ertapenem (Invanz) does not cover | show 🗑
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| Monobactam drug & form | show 🗑
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| show | Azactam
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| show | Gram negative ONLY
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| show | B
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| show | Well tolerated
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| show | Gentamicin, Tobramycin & amikacin (all IV; not absorbed well)
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| show | Gram - (Pseudomonas)
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| show | Abscesses
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| Aminoglycoside Pregnancy category | show 🗑
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| show | Always used in combo: serious gram (-) infections or b-lactam for synergy
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| show | Erythromycin (Iv, PO, Opth). Clarithromycin (Biaxin) - PO. Azithromycin (Zithromax) - IV/PO
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| show | Biaxin
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| Azithromycin | show 🗑
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| Macrolides Pregnancy category | show 🗑
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| Macrolides coverage | show 🗑
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| show | OM, CAP, COPD, STD
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| show | GI (take with food) & QT prolongation
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| Clarithromycin (Biaxin) DOC | show 🗑
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| Azithromycin (Zithromax) DOC | show 🗑
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| show | 68 hours
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| Fluoroquinolone drugs | show 🗑
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| Fluoroquinolone coverage | show 🗑
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| show | Legionella
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| Cipro & Levaquin cover | show 🗑
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| Fluoroquinolone pregnancy category | show 🗑
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| show | <18y.o. (arthropathy)
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| show | N/V/D, CNS (HA, restlessness), decrease seizure threshhold, tendon rupture (spontaneous - achilles), increase in AST/ALT
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| show | Aluminum/Mg antacids, sulcralfate, Ca2+, Fe2+ & Zinc - decrease absorption. Increases the effect of warfarin (except moxifloxacin & gatifloxacin)
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| Fluoroquinolone uses | show 🗑
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| Tetracycline drugs | show 🗑
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| Tetracycline coverage | show 🗑
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| show | D
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| show | < 8 y.o. (permanent discoloration of the teeth & inhibits bone growth)
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| show | CAP, STD (Chlamydia), syphilis (pen-allergic pts.), Lyme dz, acne, community acquired MRSA
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| Tetracycline ADR | show 🗑
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| Tetracycline DI | show 🗑
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| Vancomycin Forms | show 🗑
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| Vancomycin MOA | show 🗑
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| show | gram +'s (MRSA, MRSE) & mild-mod anaerobic
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| show | C
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| Vancomycin ADR | show 🗑
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| Vancomycin administration | show 🗑
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| show | Penetrates CSF
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| show | Cleocin
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| Clindamycin (Cleocin) forms | show 🗑
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| show | Lincomycin
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| Clindamycin (Cleocin) MOA | show 🗑
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| show | **anaerobes** Strep & S. aureus (MRSA)
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| Clindamycin (Cleocin) use | show 🗑
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| show | N/V/D & rash - can cause C. Diff
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| show | Flagyl
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| show | Inhibits DNA synthesis
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| Clindamycin (Cleocin) coverage | show 🗑
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| show | Abdominal abscess, C. diff, Rx trich, & H. pylori
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| show | B (avoid 1st trimester)
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| Clindamycin (Cleocin) special abilities | show 🗑
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| Clindamycin (Cleocin) ADR | show 🗑
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| TMP/SMZ | show 🗑
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| show | PO or IV
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| show | Inhibits folic acid synthesis (static)
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| TMP/SMZ (Trimethoprim/Sulfamethoxazole) pregnancy category | show 🗑
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| show | Staph, strep, GNR's & Pneumocystis (prophylaxis for HIV pt.)
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| show | UTIs, gram - infections, MRSA
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| show | PCP
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| show | Rash, CNS disturbances, photosensitivity, GI Sx.
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| TMP/SMZ (Trimethoprim/Sulfamethoxazole) Increase toxcity of... | show 🗑
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| Rifampin Form | show 🗑
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| show | Inhibits bacterial synthesis
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| show | TB, Meningococcal prophylaxis, nasal carriers of MRSA
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| Rifampin ADR | show 🗑
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| Linezolid | show 🗑
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| Linezolid (Zyvox) forms | show 🗑
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| Linezolid (Zyvox) class | show 🗑
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| show | Staph (MRSA), Coag (-) staph, strept, enterococci (VRE). Minor against anaerobes
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| Linezolid (Zyvox) ADR | show 🗑
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| Linezolid (Zyvox) uses | show 🗑
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| show | Quinupristin/Dalfopristin
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| Synercide Quinupristin/Dalfopristin class | show 🗑
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| show | IV via central line only!
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| show | MRSA, VRE
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| show | Myalgia, arthalgia
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| show | Rarely
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| Daptomycin Form | show 🗑
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| show | MRSA
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| Daptomycin use | show 🗑
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| Tygecycline coverage | show 🗑
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| Mupirocin | show 🗑
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| show | Topical
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| Mupirocin (Bactroban) use | show 🗑
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| show | Macrodantin
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| Nitrofurantoin (Macrodantin) coverage | show 🗑
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| show | B
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| Nitrofurantoin (Macrodantin) DI | show 🗑
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| show | G6PD deficiency = interstitial pulmonary fibrosis with chronic use.
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| Nitrofurantoin (Macrodantin) use | show 🗑
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| Bacteria that must be treated for > 4 weeks | show 🗑
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| show | **Nafcillin, oxacillin, dicloxacillin, cefazolin
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| Anti-MRSA | show 🗑
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| Anti-anaerobic | show 🗑
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| show | pipercillin/tazobactam, aminoglycosides, ceftazadime, cefepime, imipenem, meropenem, ciprofloxacin, levofloxacin.
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Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
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You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
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