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Hematology

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Question
Answer
show Disorders of erythrocytes (RBCs), platelets,leukocytes (WBCs),coagulation  
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Anemia   show
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show Pallor ↓ Hemoglobin ↓ Blood flow to the skin Jaundice ↑ Concentration of serum bilirubin Pruritus ↑ Serum and skin bile salt concentrations  
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show Tachycardia Tachypnea Fatigability Dyspnea Orthopnea Orthostatic hypotension MI  
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show Inability to concentrate Vertigo Irritability  
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show Anorexia Abdominal pain  
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show Mild = Hb 10 to 14 g/dl May exist without symptoms Possible symptoms Palpitations, dyspnea, diaphoresis Moderate = Hb 6 to 10 g/dl Increased cardiopulmonary symptoms Experienced at rest or during activity  
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Diagnostic findings   show
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Iron-Deficiency Anemia   show
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show Inadequate dietary intake 5% to 10% of ingested iron is absorbed Malabsorption Blood loss Hemolysis  
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show Laboratory findings Hb, Hct, MCV, MCH, MCHC, reticulocytes, serum iron, TIBC, bilirubin, platelets Stool guaiac test Endoscopy Colonoscopy  
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Iron-Deficiency Anemia Collaborative Care   show
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Iron-Deficiency Anemia Nursing Management   show
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show Classification Cobalamin (vitamin B12) deficiency Folic acid deficiency  
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Cobalamin Deficiency Etiology   show
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Cobalamin Deficiency Clinical Manifestations   show
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Cobalamin Deficiency Diagnostic Studies   show
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Cobalamin Deficiency Collaborative Care   show
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show Familial disposition Early detection and treatment can lead to reversal of symptoms Ensure that injuries are not sustained because of the patient’s diminished sensations to heat and pain  
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Folic Acid Deficiency   show
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show Insidious onset Absence of neurologic problems Treated by replacement therapy Encourage patient to eat foods with large amounts of folic acid  
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Anemia of Chronic Disease   show
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show ↑ Serum ferritin ↑ Iron stores Normal folate and cobalamin levels Treating underlying cause is best Rarely blood transfusions Erythropoietin therapy  
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Chronic Blood Loss   show
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show Identify source Stop bleeding Possible use of supplemental iron  
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Acute Blood Loss   show
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Acute Blood Loss Clinical Manifestations   show
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show Laboratory data do not adequately assess RBC problems for 2 to 3 days  
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show Replacing blood volume to prevent shock Identifying the source of the hemorrhage Stopping blood loss Correcting RBC loss  
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Aplastic Anemia   show
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Aplastic Anemia   show
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show Symptoms of anemia Infection Purpura Lymphadenopathies Splenomegaly Retinal hemorrhages  
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show Decreased RBCs, WBCs and platelets Decreased reticulocyte count (immature RBCs) Bone marrow examination Decrease activity of bone marrow/no cell activity  
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show Remove the cause Treat symptoms Transfusions RBCs Platelets Bone marrow transplant/peripheral stem cell transplant  
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show Activity intolerance Imbalanced nutrition: Less than body requirements Ineffective therapeutic regimen management Potential complication: Hypoxemia  
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show Goals Maintain adequate oxygenation Assume normal activities of daily living Maintain adequate nutrition Develop no complications related to anemia Monitor labs Monitor oxygenation status Monitor for signs of bleeding Pace activities to avoid fati  
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Anemia Nursing Implementation   show
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show Excessive production of RBCs as well as platelets and leukocytes Increased blood viscosity Congestion of blood in tissues Liver Spleen Evolves to Acute Myelocytic Leukemia (AML)  
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Polycythemia Clinical manifestations   show
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show Increased RBCs Increased Hgb & Hct Increased uric acid levels (due to increased RBC destruction)  
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Polycythemia Collaborative Care   show
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show Pain management Monitor for organ failure Monitor for altered nutrition (less than body requirements) Monitor for complications post phlebotomy Orthostatic hypotension Tachycardia Decreased LOC Chest pain  
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show Reduction of platelets below 150,000/ul Immune thrombocytopenic purpura (ITP) Most common acquired form Autoimmune – platelets destroyed in the spleen Thrombotic thrombocytopenic purpura Uncommon Cause: unknown  
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show Heparin Induced Thrombocytopenia an Thrombosis Syndrome (HITTS)  
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show Epistaxis(nose bleed) Gingival bleeding Petechiae Purpura Ecchymosis Internal bleeding  
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Thrombocytopenia Complications   show
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show Stop bleeding Replace coagulation factors Blood & blood product transfusion Plasmaphoresis Treat underlying cause Splenectomy Medications Corticosteriods Imuran  
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Thrombocytopenia Safety   show
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Thrombocytopenia Safety   show
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Thrombocytopenia Nursing Management   show
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show Nutrition Promote erythropoiesis – Folic acid, B12 - RBC maturation Iron, B6 - Hgb synthesis Vitamin C - converts folic acid to active form, Fe absorption  
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Focus Assessment/Complications Cardiovascular   show
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show Integument: petechiae/ecchymosis Hematological: prolonged bleeding w/ invasive procedures; occult blood Gastrointestinal: splenomegaly; abdominal pain & distention Neuro: CVA - cerebral bleed; retinal bleed Musculoskeletal: hemarthrosis  
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Neutropenia   show
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Neutropenia Etiology   show
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show Low WBC Low grade fever  
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Neutropenia Complication   show
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Neutropenia Diagnostic Findings   show
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Neutropenia Collaborative Care   show
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Neutropenia Nursing Management Fluids & Electrolytes   show
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Neutropenia Nursing Management Nutrition   show
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Neutropenia Nursing Management Safety   show
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Neutropenia Nursing Management Discharge teaching   show
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Leukemia   show
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Leukemia Etiology   show
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show Relate to problems caused by Bone marrow failure Overcrowding by abnormal cells Inadequate production of normal marrow elements Anemia, thrombocytopenia, neutropenia  
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Leukemia Clinical Manifestations   show
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Leukemia Diagnostic Studies   show
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Leukemia Collaborative Care   show
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show Eliminate leukemic cells from patient’s body Replaced with those of an HLA-matched Sibling Volunteer Identical twin Patient’s own stem cells removed before  
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show Assess for signs and symptoms of disease progression,infection,bleeding,Provide nutrition,Prevent fatigue,Promote safety Observe for side effects of tx  
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show Patient empowered by knowledge of the disease& tx can have a more positive outlook& improved quality of life Nurses face special challenges when meeting the intense psychosocial needs of a patient with leukemia  
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show Hereditary coagulation disorder Sex-linked recessive disorder Von Willebrand’s disease Hemophilia A (most common) Hemophilia B  
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show Assays for factors VIII, IX and vWF PTT is prolonged due to the intrinsic pathway problem Normal platelets and PT  
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show Persistent and prolonged bleeding from injuries Delay of onset of bleeding Subcutaneous echymosis and subcutaneous hematomas Gingival bleeding GI bleeding Hematuria Hemarthrosis  
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Hemophilia Collaborative Care   show
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Hemophilia Nursing Management   show
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show Imbalance between coagulation and anticoagulation Caused by sepsis, anoxia, burns, multiple trauma, amniotic fluid embolus, snake bites, metabolic acidosis, hypotension 80% mortality rate Net effect is hemorrhage  
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DIC Diagnostic Findings   show
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show Related to the cause Purpura Ecchymoses Bleeding from various sites with pain and clinical manifestations associated with bleeding Hypotension Shock Death  
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show Treat cause Symptom management Administer blood products Replace clotting factors Fresh frozen plasma (FFP) Cryoprecipitate  
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show Assess for hemorrhage Implement bleeding precautions Monitor for signs of fluid overload (transfusions) Assess for signs of renal failure Assess for signs of respiratory failure Supportive care  
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show Hemoglobin  
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show Phagocytosis  
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