Asthma
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| under sympathetic control | nor-adrenaline
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| under parasympathetic control | ACh
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| chronic inflammatory disorder of the airways, with acute episodes of airway obstruction due to bronchospasm, mucosal oedema, excess mucus production | Asthma
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| begins in childhood, sensitivity to external allergens (typically on inhalation) | extrinsic (atopic) asthma
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| reaction to internal non-allergic factors, no obvious role of allergen in inflammatory response, IgE synthesis | intrinsic (non-atopic) asthma
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| pollen, air pollution, animal dander, house dust/ mould, feather pillows, food additives, noxious fumes, tobacco smoke | extrinsic allergens
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| irritants, emotional stress/anxiety, respiratory infections, endocrine changes, temperature/ humidity changes, coughing/laughing, genetic factors | intrinsic allergens
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| responsible for vasodilation and bronchospasm element | histamine
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| increase mucus secretion, further obstructing airway & causing more histamine release | leukotrines
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| major component of inflammatory response, attracting more inflammatory mediators to increase the response | cytokines
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