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intro to pharm, PD and PK

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Pharmacodynamics-   show
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show What the body does to drugs.  
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Ligand-   show
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The 4 major types of receptors-   show
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Ions-   show
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Cations-   show
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Anions-   show
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Ion Channels are what type of receptors?   show
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Examples of ion channels-   show
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show voltage gated, ligand-gated, second messenger.  
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Voltage gated channels-   show
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Membrane potential-   show
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show Ligand binds to open channels  
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Resting potential-   show
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show Positive ions flow into the cell.  
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show Negative ions flow into the cell.  
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show G-Protein channel receptors that are exposed to prolonged exposure to a agonist which results in decreased number of functional receptor sites.  
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show Definitive end product of receptor desensitization.  
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show Enzyme that adds a large, negatively charged phosphate group to protein. Used in enzyme-linked receptors.  
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Phosphorylation-   show
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Examples of Enzyme-linked receptors-   show
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Examples of G-protein receptors-   show
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show cytpoplasmic or nuclear receptors. Ligands must pass through the cell membrane to reach receptors.  
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show Steroids, estrogen.  
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Non-receptor drugs   show
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What type of receptor is also known as a 7 transmembrane domain receptor?   show
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What type of receptor is also known as a catalytic receptor, where binding an extracellular ligand causes specific activity on the intracellular side?   show
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What type of receptor is located inside the cell rather than on it's membrane?   show
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What type of receptor is essential in neuronal activities, and can also be called a ligand gated receptor channel?   show
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What type of receptor is the most abundant receptor within the body?   show
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show Second messenger.  
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show Excitatory channels.  
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show inhibitory channels.  
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show Any dangerous reaction to a drug.  
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Untoward reaction-   show
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Ampule-   show
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show Something opposing or resisting the action of another.  
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Antidote-   show
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show Something that makes an indicated treatment or procedure inadvisable. Has to be indicated.  
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show Tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action.  
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Cumulative effect-   show
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show Type of reaction that is totally unpredictable, and unique to an individual.  
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show Something that points to, or suggests the proper treatment of a disease.  
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Physical Dependence-   show
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Potentiation-   show
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Psychological dependence-   show
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Summation-   show
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show Rapid appearance of progressive decrease in response to a given dose after repetitive administration of a pharmacologically active substance.  
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Side effect-   show
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Synergism-   show
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show Diminished response to a drug, which occurs when the drug is used repeatedly and the body adapts to the continued presence of the drug.  
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Vial-   show
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show Curative, Prophylactic, Diagnostic, Palliative, Replacement, destructive  
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Curative-   show
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show Medications that prevent diseases. (vaccines)  
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Diagnostic-   show
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show Medications that make patients more comfortable. (morphine)  
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Replacement-   show
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Destructive-   show
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Rank the controlled substance schedules from most abused to lowest risk   show
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Biologic-   show
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show Therapies that involve plant extracts, herbs, vitamins, minerals, and dietary supplements.  
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show Covalent  
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show The amount of time a ligand takes to bind to a receptor.  
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K (off) receptors-   show
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show How binding between a ligand and a receptor influences the body. Examines the safety of the drug.  
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show Plots the fraction of a population that responds to a given dose of medication.  
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