intro to pharm, PD and PK
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Pharmacodynamics- | show 🗑
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show | What the body does to drugs.
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Ligand- | show 🗑
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The 4 major types of receptors- | show 🗑
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Ions- | show 🗑
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Cations- | show 🗑
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Anions- | show 🗑
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Ion Channels are what type of receptors? | show 🗑
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Examples of ion channels- | show 🗑
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show | voltage gated, ligand-gated, second messenger.
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Voltage gated channels- | show 🗑
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Membrane potential- | show 🗑
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show | Ligand binds to open channels
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Resting potential- | show 🗑
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show | Positive ions flow into the cell.
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show | Negative ions flow into the cell.
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show | G-Protein channel receptors that are exposed to prolonged exposure to a agonist which results in decreased number of functional receptor sites.
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show | Definitive end product of receptor desensitization.
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show | Enzyme that adds a large, negatively charged phosphate group to protein. Used in enzyme-linked receptors.
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Phosphorylation- | show 🗑
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Examples of Enzyme-linked receptors- | show 🗑
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Examples of G-protein receptors- | show 🗑
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show | cytpoplasmic or nuclear receptors. Ligands must pass through the cell membrane to reach receptors.
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show | Steroids, estrogen.
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Non-receptor drugs | show 🗑
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What type of receptor is also known as a 7 transmembrane domain receptor? | show 🗑
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What type of receptor is also known as a catalytic receptor, where binding an extracellular ligand causes specific activity on the intracellular side? | show 🗑
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What type of receptor is located inside the cell rather than on it's membrane? | show 🗑
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What type of receptor is essential in neuronal activities, and can also be called a ligand gated receptor channel? | show 🗑
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What type of receptor is the most abundant receptor within the body? | show 🗑
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show | Second messenger.
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show | Excitatory channels.
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show | inhibitory channels.
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show | Any dangerous reaction to a drug.
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Untoward reaction- | show 🗑
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Ampule- | show 🗑
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show | Something opposing or resisting the action of another.
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Antidote- | show 🗑
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show | Something that makes an indicated treatment or procedure inadvisable. Has to be indicated.
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show | Tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action.
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Cumulative effect- | show 🗑
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show | Type of reaction that is totally unpredictable, and unique to an individual.
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show | Something that points to, or suggests the proper treatment of a disease.
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Physical Dependence- | show 🗑
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Potentiation- | show 🗑
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Psychological dependence- | show 🗑
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Summation- | show 🗑
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show | Rapid appearance of progressive decrease in response to a given dose after repetitive administration of a pharmacologically active substance.
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Side effect- | show 🗑
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Synergism- | show 🗑
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show | Diminished response to a drug, which occurs when the drug is used repeatedly and the body adapts to the continued presence of the drug.
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Vial- | show 🗑
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show | Curative, Prophylactic, Diagnostic, Palliative, Replacement, destructive
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Curative- | show 🗑
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show | Medications that prevent diseases. (vaccines)
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Diagnostic- | show 🗑
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show | Medications that make patients more comfortable. (morphine)
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Replacement- | show 🗑
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Destructive- | show 🗑
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Rank the controlled substance schedules from most abused to lowest risk | show 🗑
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Biologic- | show 🗑
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show | Therapies that involve plant extracts, herbs, vitamins, minerals, and dietary supplements.
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show | Covalent
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show | The amount of time a ligand takes to bind to a receptor.
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K (off) receptors- | show 🗑
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show | How binding between a ligand and a receptor influences the body. Examines the safety of the drug.
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show | Plots the fraction of a population that responds to a given dose of medication.
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