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All types of anemias

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Question
Answer
Anemia   reduction in circulating RBCs or hemoglobin resulting in poor tissue perfusion, blood flow shunted to vital organs  
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gerontologic considerations for anemia   anemia is not normal, often related to an underlying cause and signs/symptoms may go unrecognized  
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common s/s that may be associated with normal aging   pallor, increased fatigue, confusion. ataxia, worsening respiratory pr cardiovascular problems  
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iron deficiency anemia causes   inadequate dietary intake, malabsorption, blood loss,  
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clinical signs of iron deficiency anemia   pallor, glossitis. chelitis, headache, paresthesias  
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treatment of iron deficiency anemia   treat underlying disease, replace iron with oral supplements or transfusion of packed RBCs  
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oral iron supplements considerations   best absorbed in acidic environment so take with vitamin C or orange juice take an hour before meals liquid iron may stain teeth  
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side effects of oral iron   constipation, heartburn, diarrhea and black stools  
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megaloblastic anemia   group of disorders caused by impaired DNA synthesis and presence of megaloblasts majority results from deficiency in B12 or folic acid  
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treatment of megaloblastic anemia   b12 or folic acid supplements given in form of IM injections daily for 2 weeks - B12  
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chronic disease anemia   uderproduction of RBCs and shortening of RBC survival  
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chronic disease anemia causes   cancer, autoimmune and infectious diseases, heart failure and chronic inflammation  
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treatment of chronic disease anemia   treat underlying chronic disorder  
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aplastic anemia   Pancytopenia along with hypocellular bone marrow  
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diagnostic studies   decreased hemoglobin, WBCs, and platelets bone marrow biopsy shows hypocellular with increased fat content  
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supportive care for aplastic anemia   prevent complications from hemorrhage and infection stem cell transplant immunosuppression  
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causes of aplastic anemia   chemicals and toxins, drugs (NSAIDs, anti-inflammatory, anti-microbials), radiation, viral / bacterial infections  
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blood loss anemia diagnostic studies   decreased RBCs, hemoglobin and hematocrit but values will not decrease immediately  
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treatment for blood loss anemia   replace fluid, identify source of loss, may require transfusion, may need supplemental iron to treat anemia,  
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Anemia due to destruction   hemolytic (destruction of RBCs at a rate that exceeds production)  
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symptoms of anemia due to destruction can cause...   liver and spleen to enlarge, jaundice and elevated bilirubin levels  
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treatment of anemia due to destruction   focus on maintaining renal function  
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assessment of anemia   decrease circulating volume - signs of shock decreased oxygenation- signs of impaired gas exchange compensatory mechanisms - increased HR  
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RBC normal   men - 4.32-5.72 women- 3.9-5.0  
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hgb normal   men- 13.2 -17.3 women- 11.7-15.5  
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hct normal   men- 39-50 women- 36-47  
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wbc count normal   4,000-11,000  
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platelet normal   150,000-450,000  
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b12 normal   200-835  
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folate normal   3-16  
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iron normal   50-175  
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