CMI-Fall 2011
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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show | -Sx < 6mo
-Self-repair, resolution of sx, no permanet damage
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What defines chronic hepatis? | show 🗑
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What is fulminant hepatitis? | show 🗑
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Explain blood supply to and from liver: | show 🗑
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The liver breaks down toxic products, what is the pathway of breakdown for a certain toxic byproduct of muscle breakdown? | show 🗑
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What is the liver's role in drug conversion? | show 🗑
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Which 2 important hormones that are synthesized from cholesterol are regulated by the liver? | show 🗑
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What are some symptoms suggestive of acute hepatitis? | show 🗑
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show | ALT,AST,Alk Phos,GGT
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What is a NL aminotransferase value? | show 🗑
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W/acute hepatitis, aminotransferase will be elevated to? | show 🗑
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show | -Acetaminophen
-Ischemic
-Unusual virus
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show | Drugs, ischemia, viruses
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show | Alcohol
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show | Only seen in HBV infected pts
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Routes of transmission of HAV? | show 🗑
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HAV IgG + indicates? | show 🗑
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HBV route of transmission? | show 🗑
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show | Pt HAS been exposed to virus
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If HepB surface ag +? | show 🗑
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IgM anti-HBc? | show 🗑
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show | Lifelong marker/past chronic infection
-Does not indicate immunity and is not induced by vaccine
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HBsAG present w/ IgM anti-HBc? | show 🗑
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show | Appears shortly before sxs
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Neg HBcAb? | show 🗑
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show | No infection
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show | No immunity
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Pos HBcAg? | show 🗑
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Pos HBsAg? | show 🗑
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show | Immunity
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Interpret: Neg HBcAb, Neg HBsAg, Neg HBsAb? | show 🗑
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Interpret: +HBcAb, -HBsAg, +HBsAb? | show 🗑
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Interpret: Core ABNeg, HBsAg Neg, +HBsAb? | show 🗑
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+HBeAg? | show 🗑
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Anti HCV negative? | show 🗑
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show | Acute, Chronic, Previous; confirm results w/ RIBA
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show | Marker of active infection
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show | Viral load; numerical answer
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Genotype of HCV? | show 🗑
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show | Chronic HBV or HCV
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What is chronic HBV the CHIEF cause of? | show 🗑
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show | Cirrhosis
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What are some steps to take to prevent Viral Hep B? | show 🗑
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HAV is inactivated and w/o preservatives, who can it be given to? and where is it given? | show 🗑
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show | -0,1,6 mo's
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show | -All US <19 y.o.
-Health care workers w/ possibility of blood exposure
-Unvacc ppl w/MSM, IVDU, STD, multiple sexual partners
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show | -Accelerated combo HAV/HBV vaccine at days
0,7,21
-Booster @ 1 yr
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show | -Abx
-CNS drugs
-MSK drugs
-GI drugs
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What is the MC cause of fulminant hepatic failure? | show 🗑
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show | Females (70-80% of cases)
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show | -^AST, ALT, bilirubin
-NORMAL Alk Phos and GGT
-IgG>2x ULN
(not seen in pts w/high alcohol/drug hx)
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show | Prednisone (systemic steroids)
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What is hereditary hemochromatosis? | show 🗑
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What is the earliest and most sensitive test for hereditary hemochromatosis? | show 🗑
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What is the form that iron is stored in, in the body? | show 🗑
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show | Bx: hepatic iron index
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What dz involves copper overload? | show 🗑
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Clinical features of wilson's dz? | show 🗑
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show | a-1 antitrypsin defic (damages lung tissue and defective proteins accum in liver)
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show | Genotype testing:
MM=NL
ZZ=assoc w/cirrhosis
MZ=assoc w/lung or liver dz
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show | a-l antitrypsin deficiency (bc diff't genotype, so can get rid of dz!)
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