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CMI-Fall 2011

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show -Sx < 6mo -Self-repair, resolution of sx, no permanet damage  
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What defines chronic hepatis?   show
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What is fulminant hepatitis?   show
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Explain blood supply to and from liver:   show
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The liver breaks down toxic products, what is the pathway of breakdown for a certain toxic byproduct of muscle breakdown?   show
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What is the liver's role in drug conversion?   show
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Which 2 important hormones that are synthesized from cholesterol are regulated by the liver?   show
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What are some symptoms suggestive of acute hepatitis?   show
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show ALT,AST,Alk Phos,GGT  
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What is a NL aminotransferase value?   show
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W/acute hepatitis, aminotransferase will be elevated to?   show
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show -Acetaminophen -Ischemic -Unusual virus  
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show Drugs, ischemia, viruses  
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show Alcohol  
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show Only seen in HBV infected pts  
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Routes of transmission of HAV?   show
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HAV IgG + indicates?   show
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HBV route of transmission?   show
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show Pt HAS been exposed to virus  
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If HepB surface ag +?   show
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IgM anti-HBc?   show
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show Lifelong marker/past chronic infection -Does not indicate immunity and is not induced by vaccine  
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HBsAG present w/ IgM anti-HBc?   show
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show Appears shortly before sxs  
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Neg HBcAb?   show
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show No infection  
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show No immunity  
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Pos HBcAg?   show
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Pos HBsAg?   show
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show Immunity  
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Interpret: Neg HBcAb, Neg HBsAg, Neg HBsAb?   show
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Interpret: +HBcAb, -HBsAg, +HBsAb?   show
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Interpret: Core ABNeg, HBsAg Neg, +HBsAb?   show
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+HBeAg?   show
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Anti HCV negative?   show
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show Acute, Chronic, Previous; confirm results w/ RIBA  
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show Marker of active infection  
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show Viral load; numerical answer  
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Genotype of HCV?   show
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show Chronic HBV or HCV  
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What is chronic HBV the CHIEF cause of?   show
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show Cirrhosis  
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What are some steps to take to prevent Viral Hep B?   show
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HAV is inactivated and w/o preservatives, who can it be given to? and where is it given?   show
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show -0,1,6 mo's  
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show -All US <19 y.o. -Health care workers w/ possibility of blood exposure -Unvacc ppl w/MSM, IVDU, STD, multiple sexual partners  
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show -Accelerated combo HAV/HBV vaccine at days 0,7,21 -Booster @ 1 yr  
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show -Abx -CNS drugs -MSK drugs -GI drugs  
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What is the MC cause of fulminant hepatic failure?   show
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show Females (70-80% of cases)  
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show -^AST, ALT, bilirubin -NORMAL Alk Phos and GGT -IgG>2x ULN (not seen in pts w/high alcohol/drug hx)  
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show Prednisone (systemic steroids)  
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What is hereditary hemochromatosis?   show
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What is the earliest and most sensitive test for hereditary hemochromatosis?   show
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What is the form that iron is stored in, in the body?   show
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show Bx: hepatic iron index  
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What dz involves copper overload?   show
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Clinical features of wilson's dz?   show
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show a-1 antitrypsin defic (damages lung tissue and defective proteins accum in liver)  
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show Genotype testing: MM=NL ZZ=assoc w/cirrhosis MZ=assoc w/lung or liver dz  
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show a-l antitrypsin deficiency (bc diff't genotype, so can get rid of dz!)  
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