Exam 1 Word Scramble
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| Term | Definition |
| Immunity | body's ability to resist infectious disease |
| Antigen | any foreign substance that is non self |
| Nonspecific Immunity | present at birth and provides immediate short-term protection from antigen, physical barriers and chemical barriers (white blood cells, mucus), includes Phagocytes |
| Specific Immunity | primed by initial exposure to antigen of specific pathogen, responds quickly to antigens and prevents future exposures to create same response |
| Pathogens | disease causing microorganisms |
| Phagocytes | leukocytes that destroy pathogens |
| Example of nonspecific immunity | Phagocytes |
| Humoral Immunity | due to action of antibodies B Cells primary form of protection |
| B Cells | antibodies are proteins produced by white blood cells called B lymphocytes or b cells |
| Cell-mediated Immunity | defense against viruses, abnormal cells, and other intracellular pathogens, and it is responsible for rejecting tissue grafts and organ transplants. T cells/lymphocytes responsible |
| T Cells types | Helper T Cell and Cytotoxic T Cells- |
| Helper T Cell | divides producing cytotoxic t cells |
| Cytotoxic T Cells | activated by antigen and divide and produce clones and memory t cells |
| Pars of Specific Immunity | Humoral Immunity, B Cells, Cell-mediated Immunity, T Cells |
| Important Immunoglobulins | IgM and IgE |
| IgM | First antibody produced in primary response to antigen, activates complement |
| IgE | Stimulates release of histamines and other chemicals that mediate inflammation and allergic responses |
| Immune system and aging | Immune system function declines, Thymus atrophies, Fewer T cells |
| Types of Diagnostic Testing | Agglutination reactions, Enzyme immunoassay (EIA), Western blot, Fluorescent antibody techniques, Flow cytometry, C-reactive protein, Erythrocyte sedimentation |
| Agglutination reactions | detect bacterial and viral diseases used in blood typing |
| Enzyme immunoassay (EIA) | enzyme to label antibody or antigen, widely used |
| Western blot | detects antibodies in serum |
| Fluorescent antibody techniques | use antibody labeled with fluorescent molecule to detect antigen |
| Flow cytometry | identifies and counts cells that have a particular antigen |
| Erythrocyte sedimentation | measure general levels of inflammation in body (same as C-reactive protein) |
| C-reactive protein | measure general levels of inflammation in body (same as Erythrocyte sedimentation) |
| Autoimmunity | immune system fails to distinguish between self and non self attacks what it sees as non self |
| Autoantibodies | antibodies that person develops to their own tissues or own self antigens |
| Raynaud's phenomenon | Secondary, areas of skin turn white or blue |
| Overview of Lupus | skin joints heart blood lung brain 90% of women most diagnoses between 15-44 y/o idiopathic etiology-Systemic (many body systems involved), Cutaneous (only skin), Drug-induced, Neonatal |
| Scleroderma Overview | Name means hard skin, Chronic autoimmune disease of connected tissue, Localized scleroderma (only skin) Systemic sclerosis scleroderma (skin+internal organs)-Limited cutaneous SSC above the elbows, skin and feet below knees-Diffuse cutaneous all areas |
| Sjögren's Syndrome Overview | Chronic, slow progressive autoimmune disease affects moisture producing glands, exocrine |
| Allergy Overview | Extreme immune response to a harmless antigen Immediate (Type I), Cytotoxic (Type II), Immune-complex (Type III), Delayed (Type IV), Histamine dilates blood cells leaks plasma into tissues |
| Acquired Immunodeficiency Syndrome and HIV Overview | Reduction of helper T cells, Increase opportunistic infections |
| Hodgkin's Lymphoma overview | Cancer of the immune system, Reed-Sternberg cells |
| Non-Hodgkin's Lymphoma Overview | Cancer of the lymphocytes |
Created by:
LemonLinds
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