Cerebelleum Word Scramble
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| Question | Answer |
| Vestibulocerebellum: Input and Pathway | Inner Ear (vestibular labryinth)-Ipsilateral, Vestibular nuclei (esp. inferior)-Bilateral, and Inferior Olive Pathway: Inferior cerebellar peduncle |
| Vestibulocerebellum: Output (including Function)and Pathway | Vestibular nuclei (esp. medial and superior): movement of eyes (lateral): axial muscles and limb extensors Pathway: inferior cerebellar peduncle |
| What is unique about projections from the vestibulocerebellum? | Purkinje cells project directly to targets outside of the cerebellum |
| Vermal Spinocerebellum: Input and Pathway | Dorsal spinocerebellar and cuneocerebellar tracts (via inferior peduncle) Vestibular nuclei (via inferior peduncle), Ventral spinocerebellar tract (via superior peduncle), and some input from inferior olive |
| Vermal Spinocerebellum: Output and Pathway | Fastigial nucleus to vestibular nuclei via inferior cerebellar peduncle |
| What is the function of the vermal spinocerebellum? | For posture and balance via sensory input from spinocerebellar (proprioception) and vestibular input (some overlap w/ vestibulcerebellar functions) |
| Paravermal Spinocerebellum: Input and Pathway | Dorsal spinocerebellar and cuneocerebellar tract (via inferior peduncle), ventral spinocerebellar tract (via superior peduncle), and alsom some inferior olive input |
| Paravermal Spinocerebellum: Output and Pathway | Interposed nuclei to contralateral red nucleus and contralateral thalamus via superior cerebellar peduncle |
| What is the function of the paravermal spinocerebellum? | To adjust activity of distal muscles in response to spinocerebellar input and coordinating with motor cortical areas (via thalamus) |
| Are projections from the red thalamus ispilateral or contralateral? | Contralateral-therefore, the cerebellar interposed nuclei control ipsilateral posture and coordination (a double cross) |
| Which functional cerebellum projects to the magnocellular red nucleus? | Th interposed nuclei of the perivermal spinocerebellum? |
| Which functional cerebellum projects to the parvocellular red nucleus? | The dentate nuclei of the cerebrocerebellum |
| Cerebrocerebellum: Input and Pathway | Contralateral cerebral hemisphere via cerebral peduncles, basal pontine nuclei and middle cerebellar peduncle Also the inferior olivary nucleus |
| Cerebrocerebellum: Output and Pathway | Dentate nuclei to contralateral red nucleus and contralateral (VA/VL) thalamus via superior cerebellar peduncle |
| What is the function of the cerebrocerebellum? | Planning of voluntary movements, motor memory and learning, input of sensory stimuli (ESPECIALLY VISION) |
| What does the inferior olive project to and what kind of fiber is it associated with? | Projects to ALL portions of the cerebellum and associated with climbing fibers. |
| Where do parvocellular neurons of the red nucleus project to and is it ipsi or contralateral? | It sends ispilateral projections to the inferior olive , forming a loop. |
| Where do magnocellular neurons of the red nucleus project to and is it ipsi or contralateral? | It sends contralateral projections down through the rubrospinal tract. |
| What do mossy fibers project to? | The granule cells AS WELL as the deep cerebellar nuclei |
| What corresponds to the deep cerebellar nuclei in the flocculonodular system? | The vestibular nuclei |
| What is the function of the inferior olive? | Provides an error signal when integrating sensory input to potentiate and depress purkinje cells via climbing fibers |
| What do vermal lesions present as? | Abnormal eye movements, impaired balance, truncal ataxia |
| What do paravermal lesions present as? | appendicular ataxia |
| What do lateral lesions present as? | impairment of fine motor activities, impaired motor learning, poduces clinical deficits on IPSILATERAL side of lesion |
| What does increased climbing fiber activity do to the cerebellar motor learning circuit? | Induces LTD of the parallel fiber-Purkinje cell synapse, increasing total motor command output. |
| What does decreased climbing fiber activity do to the cerebellar motor learning circuit? | Induces LTP of the parallel fiber-Purkinje cell synapse, decreasing total motor command output. |
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bloodisland
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