In each blank, try to type in the
word that is missing. If you've
typed in the correct word, the
blank will turn green.
If your not sure what answer should be entered, press the space bar and the next missing letter will be displayed. When you are all done, you should look back over all your answers and review the ones in red. These ones in red are the ones which you needed help on. Question: atorvastatin (Lipitor) classification and Answer: HMG-CoA Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production Question: fluvastatin (Lescol) classification and Answer: HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by lipoprotein production Question: lovastatin (Mevacor) and useAnswer: HMG-CoA Reductase Inhibitor (Statin); used to hyperlipidemia by restricting lipoprotein production Question: pitavastatin (Livalo) and useAnswer: HMG-CoA Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production Question: pravastatin (Pravachol) classification and Answer: HMG-CoA Reductase Inhibitor (Statin); used to hyperlipidemia by restricting lipoprotein production Question: simvastatin (Zocor) and useAnswer: HMG-CoA Reductase Inhibitor (Statin); used to hyperlipidemia by restricting lipoprotein production Question: rosuvastatin (Crestor) classification and Answer: HMG-CoA Reductase (Statin); used to treat hyperlipidemia by restricting lipoprotein production Question: niacin (Nicobid, Niaspan) classification and Answer: Niacin; used to hyperlipidemia by restricting lipoprotein production Question: nicotinic acid (Slo-Niacin, Novo-Niacin) classification and Answer: Niacin; used to treat hyperlipidemia by restricting lipoprotein Question: fenofibrate (TriCor) classification and Answer: Acid Derivative; used to treat hyperlipidemia by restricting lipoprotein production Question: gemfibrozil (Lopid) classification and Answer: Fibric Acid Derivative; used to hyperlipidemia by restricting lipoprotein production Question: cholestyramine (Questran) classification and Answer: Bile-Acid Sequestrant; used to treat hyperlipidemia by lipoprotein removal Question: (WelChol) classification and useAnswer: Bile-Acid Sequestrant; used to hyperlipidemia by increasing lipoprotein removal Question: colestipol (Colestid) and useAnswer: Bile-Acid Sequestrant; used to hyperlipidemia by increasing lipoprotein removal Question: ezetimibe (Zetia) classification and Answer: Cholesterol Absorption Inhibitor; used to treat hyperlipidemia by decreasing cholesterol Question: HMG-CoA Reductase Inhibitors (Statins) Mechanism of Action and Answer: Block of cholesterol and increase LDL receptors in liver, ↓ LDL, ↓ Triglycerides, ↑ HDL Question: HMG-CoA Reductase Inhibitors (Statins) ConsiderationsAnswer: Well tolerated with few side effects. Monitor liver enzymes and creatine kinase (if muscle or pain occurs). Question: Mechanism of Action and EffectsAnswer: Inhibits synthesis and of VLDL and LDL, ↓ LDL, ↓ Triglycerides, ↑ HDL Question: Nursing ConsiderationsAnswer: Most side effects subside with time; decreased liver may occur with high doses. Taking aspirin or NSAID 30 min before drug may prevent flushing; take drug with food. Treat elevated homocysteine levels with folic acid. Question: Fibric Acid Derivatives of Action and EffectsAnswer: hepatic synthesis and secretion of VLDL; ↓ LDL; ↓ Triglycerides; ↑ HDL Question: Fibric Acid Nursing ConsiderationsAnswer: May ↑ effects of warfarin (Coumadin) and some antihyperglycemic drugs. When used in combination with , may increase adverse effects of statins, especially myopathy. Question: Bile-Acid Sequestrants Mechanism of Action and Answer: Bind with bile acids in intestine, forming insoluble complex and in feces, resulting in removal of LDL and cholesterol; ↓ LDL Question: Bile-Acid Nursing ConsiderationsAnswer: Effective and safe for long-term use; side diminish with time. Interfere with absorption of many drugs (e.g., digoxin, thiazide diuretics, warfarin, some antibiotics [e.g., penicillins]). Question: Absorption Inhibitor Mechanism of Action and EffectsAnswer: Inhibits the absorption of cholesterol; ↓ LDL; ↑ HDL Question: Cholesterol Absorption Nursing ConsiderationsAnswer: When used with a statin, LDL is further reduced. not be used by patients with liver impairment. Question: Simvastatin (Zocor) Drug Answer: Increased risk for rhabdomyolysis when also used with (Lopid) or niacin. Signs of rhabdomyolysis: ↑ creatine kinase levels, muscle tenderness. Question: Niacin (Niaspan) Drug Answer: Instruct patient that flushing (especially of face and neck) may occur within 20 minutes after taking drug and may last for 30 to 60 . Can premedicate with aspirin or NSAID 30 minutes before to reduce flushing. Question: Gemfibrozil (Lopid) Drug Answer: May the risk of bleeding in patients taking warfarin (Coumadin). May increase the effects of antihyperglycemic drugs (e.g., repaglinide [Prandin]). Question: Nitrates of actionAnswer: Promote peripheral vasodilation, preload and afterload. Coronary artery vasodilation. Question: β-Adrenergic blocker mechanism of Answer: Inhibit sympathetic nervous stimulation of the heart. Reduce heart rate, contractility, and pressure. Decrease afterload. Question: Calcium channel Answer: Prevent calcium entry into vascular smooth muscle cells and myocytes (cardiac cells). Coronary and vasodilation. Reduce heart rate, contractility, and blood pressure. Question: ACE Inhibitor mechanism of Answer: Prevent conversion of angiotensin I to angiotensin II resulting in vasodilation. Decrease endothelial dysfunction. Useful with heart failure, tachycardia, MI, hypertension, diabetes, and chronic kidney Question: nitroglycerin (Nitrostat, NitroQuick) classification and useAnswer: Nitrate; used to treat chronic stable angina and acute syndrome Question: Translingual spray nitroglycerin (Nitrolingual) and useAnswer: ; used to treat chronic stable angina and acute coronary syndrome Question: Nitroglycerin ointment (Nitro-Bid, Nitrol) classification and Answer: ; used to treat chronic stable angina and acute coronary syndrome Question: Transdermal nitroglycerin (Transderm-Nitro, ) classification and useAnswer: Nitrate; used to chronic stable angina and acute coronary syndrome Question: -release buccal tablets (Nitrogard) classification and useAnswer: Nitrate; used to treat stable angina and acute coronary syndrome Question: Isosorbide dinitrate (Isordil, Sorbitrate) and useAnswer: Nitrate; used to treat chronic stable angina and coronary syndrome Question: IV (Nitro-Bid IV, Tridil) classification and useAnswer: Nitrate; used to treat chronic stable angina and acute coronary Question: atenolol (Tenormin) classification and Answer: β-Adrenergic Blockers; used to chronic stable angina and acute coronary syndrome Question: carvedilol (Coreg) classification and Answer: β-Adrenergic Blockers; used to treat chronic stable angina and coronary syndrome Question: esmolol (Brevibloc) classification and Answer: β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary Question: metoprolol (Lopressor) classification and Answer: β-Adrenergic Blockers; used to treat chronic stable angina and coronary syndrome Question: nadolol (Corgard) and useAnswer: β-Adrenergic ; used to treat chronic stable angina and acute coronary syndrome Question: propranolol (Inderal) classification and Answer: β-Adrenergic ; used to treat chronic stable angina and acute coronary syndrome Question: amlodipine (Norvasc) classification and Answer: Calcium Blocker; used to treat chronic stable angina and acute coronary syndrome Question: diltiazem (Cardizem) and useAnswer: Calcium Channel Blocker; used to treat chronic stable angina and coronary syndrome Question: felodipine (Plendil) and useAnswer: Calcium Channel Blocker; used to treat chronic angina and acute coronary syndrome Question: nifedipine (Procardia) and useAnswer: Calcium Channel Blocker; used to treat chronic angina and acute coronary syndrome Question: nicardipine (Cardene) classification and Answer: Calcium Channel Blocker; used to treat chronic angina and acute coronary syndrome Question: verapamil (Calan, Isoptin) and useAnswer: Calcium Channel Blocker; used to treat chronic stable angina and coronary syndrome Question: captopril (Capoten) classification and Answer: ACE Inhibitor; used to chronic stable angina and acute coronary syndrome Question: enalapril (Vasotec) classification and Answer: ACE Inhibitor; used to treat stable angina and acute coronary syndrome Question: Drug AlertAnswer: Tablet or spray needs to be administered under the tongue. Instruct patient not to combine with drugs used for erectile dysfunction (e.g., sildenafil [Viagra]). for orthostatic hypotension because it may occur after administration. Question: recombinant plasminogen activator (rPA; [Retavase]) classification and useAnswer: fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to up fibrin meshwork in clots Question: tissue plasminogen activator (tPA; alteplase [Activase]) classification and Answer: fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to up fibrin meshwork in clots Question: TNK-tPA (tenecteplase [TNKase]) and useAnswer: fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to up fibrin meshwork in clots Question: Fibrinolytic Drug Answer: If signs and symptoms of major bleeding occur (e.g., drop in BP, an increase in HR, a sudden change in the patient's level of consciousness, in the urine or stool), stop the therapy and notify the physician. |
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