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UTA NURS 4581 Meds 1 Test

Enter the letter for the matching Answer
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1.
recombinant plasminogen activator (rPA; reteplase [Retavase]) classification and use
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2.
nicotinic acid (Slo-Niacin, Novo-Niacin) classification and use
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3.
Gemfibrozil (Lopid) Drug Alert
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4.
diltiazem (Cardizem) classification and use
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5.
fenofibrate (TriCor) classification and use
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6.
Bile-Acid Sequestrants Mechanism of Action and Effects
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7.
Nitroglycerin ointment (Nitro-Bid, Nitrol) classification and use
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8.
colestipol (Colestid) classification and use
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9.
Niacin Nursing Considerations
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10.
atenolol (Tenormin) classification and use
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11.
Fibric Acid Derivatives Nursing Considerations
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12.
HMG-CoA Reductase Inhibitors (Statins) Mechanism of Action and Effects
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13.
Cholesterol Absorption Inhibitor Nursing Considerations
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14.
lovastatin (Mevacor) classification and use
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15.
ACE Inhibitor mechanism of action
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16.
Bile-Acid Sequestrants Nursing Considerations
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17.
Fibric Acid Derivatives Mechanism of Action and Effects
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18.
HMG-CoA Reductase Inhibitors (Statins) Nursing Considerations
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19.
enalapril (Vasotec) classification and use
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20.
Niacin Mechanism of Action and Effects
A.
When used with a statin, LDL is further reduced. Should not be used by patients with liver impairment.
B.
May ↑ effects of warfarin (Coumadin) and some antihyperglycemic drugs. When used in combination with statins, may increase adverse effects of statins, especially myopathy.
C.
Fibric Acid Derivative; used to treat hyperlipidemia by restricting lipoprotein production
D.
fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to break up fibrin meshwork in clots
E.
Decrease hepatic synthesis and secretion of VLDL; ↓ LDL; ↓ Triglycerides; ↑ HDL
F.
Bind with bile acids in intestine, forming insoluble complex and excreted in feces, resulting in removal of LDL and cholesterol; ↓ LDL
G.
ACE Inhibitor; used to treat chronic stable angina and acute coronary syndrome
H.
Prevent conversion of angiotensin I to angiotensin II resulting in vasodilation. Decrease endothelial dysfunction. Useful with heart failure, tachycardia, MI, hypertension, diabetes, and chronic kidney disease
I.
Well tolerated with few side effects. Monitor liver enzymes and creatine kinase (if muscle weakness or pain occurs).
J.
Most side effects subside with time; decreased liver function may occur with high doses. Taking aspirin or NSAID 30 min before drug may prevent flushing; take drug with food. Treat elevated homocysteine levels with folic acid.
K.
Block synthesis of cholesterol and increase LDL receptors in liver, ↓ LDL, ↓ Triglycerides, ↑ HDL
L.
Inhibits synthesis and secretion of VLDL and LDL, ↓ LDL, ↓ Triglycerides, ↑ HDL
M.
May increase the risk of bleeding in patients taking warfarin (Coumadin). May increase the effects of antihyperglycemic drugs (e.g., repaglinide [Prandin]).
N.
Niacin; used to treat hyperlipidemia by restricting lipoprotein production
O.
HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
P.
β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
Q.
Bile-Acid Sequestrant; used to treat hyperlipidemia by increasing lipoprotein removal
R.
Effective and safe for long-term use; side effects diminish with time. Interfere with absorption of many drugs (e.g., digoxin, thiazide diuretics, warfarin, some antibiotics [e.g., penicillins]).
S.
Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
T.
Nitrate; used to treat chronic stable angina and acute coronary syndrome
Type the Question that corresponds to the displayed Answer.
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21.
Prevent calcium entry into vascular smooth muscle cells and myocytes (cardiac cells). Coronary and peripheral vasodilation. Reduce heart rate, contractility, and blood pressure.
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22.
If signs and symptoms of major bleeding occur (e.g., drop in BP, an increase in HR, a sudden change in the patient's level of consciousness, blood in the urine or stool), stop the therapy and notify the physician.
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23.
Tablet or spray needs to be administered under the tongue. Instruct patient not to combine with drugs used for erectile dysfunction (e.g., sildenafil [Viagra]). Monitor for orthostatic hypotension because it may occur after administration.

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