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CorticosteriodsPart2
Question | Answer |
---|---|
What are mineralocorticoids? | Steriods that maintain fluid & electrolyte balance through their influence on salt & water metabolism |
What is aldosterone? | A mineralocorticoid. A hormone in the kidneys that increases sodium reabsorption from kidney tubules and water is reabsorbed along with the sodium |
What does the adrenal cortex secretes? | male (androgens) and female (estrogens & progesterone) |
What are corticosteriods useful for? | The treatment of broad spectrum diseases with an inflammatory or immunologic component. |
What are the contraindications of corticosteroids? | Systemic Fungal infections. Use in caution at risk for infections and patients with infections because they may mask signs & symptoms so infections become more severe, diabetes mellitus. |
What are the desired pharmacological effects of corticosteriods? | anti-inflammatory, innumosuppressive, anti-allergic, and anti-stress |
What is prednisone prescribed for? | Nonendocrine disorders in which anti-inflammatory, antiallergic, antistress, and immunosuppresive effects are desired |
What is Dexamethasone prescribed for? | cerebral edema associated with brain tumors, head injury because it penetrates the blood-brain barrier and achieves higher concentrations in cerbrospinal fluid |
Which of the following types of tumors may produce corticotropin(Adrenocorticotropic hormone or ACTH, antidireutic hormone, or parathrroid hormone? | Lung Tumors |
Adverse effects of systemic corticosteriods include: | Hypertension and Glucose Intolerance |
Prednisone is prescribed for | Addison's Disease |
In adrenal insufficiency, __________________ is a common symptom in critically ill patients. ________ caused by adrenal insufficiency may mimic hypovolemic or septic shock. | Hypotension |
What would the physician prescribe for a patient with adrenal insufficiency and hypotension? | Corticosteriod. If adrenal insufficiency is caused by hypotension, corticosteriods can eliminate the need for vasopressor drugs to maintain adequate tissue perfusion. |
Can corticosteriods be used for the treatment of adult respiratory distress syndrome (ARDs)? | No, they are not beneficial in early treatment or prevention of ARDS. |