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Path 13
Ovary and Fallopian Tube
Question | Answer |
---|---|
Acute salpingitis (PID) is most often a result of? | N. gonnorhea, E.coli, Chlamydia, Mycoplasma, and anaerobic bacteria |
What is it called when you have endometrial glands adn stroma outside of the endometrium commonly in the fallopian tubes | endometriosis |
BRCA1 is located on chromosome? BRCA2? | BRCA 1 is chromosome 17 and BRCA 2 is 13 |
What is the etiology of follicular and leuteal cysts | these are merely follicles and copus leoteomas that persist |
What is another name for Polycystic ovary disease? | Stein Leventhal disease |
What are signs and symptoms of Polycystic ovary disease | obesity, acne, hirsutism, infertility, +/- insulin resistance |
what are the three main groups of ovarian neoplasms | surface epithelial, germ cell, sex-cord stromal |
Serous papillary, mucinous, endometrioid, Brenner, and Clear cell are examples of? | Surface epithelial neoplasms |
teratomas, choriocarcinomas, yolk sac, embryonal and dysgerminomas are examples of? | Germ Cell Ovarian Neoplasms |
fibroma, fibrothecoma, granulosa cell tumor, sertoli-Leydig tumor, steroid tumors are examples of? | Sex cord stromal ovarian neoplasms |
What is teh hallmark of a serous papillary tumor? | ciliated columnar cells (resembles the lining of the fallopian tube) |
Gross appearance of serous cystadenomas | single or multiple smooth walled cysts |
gross appearance of serous papillary borderline tumor | multicystic but lined by papillary excrescences |
Gross appearance of serous carcinoma | may resemble borderline tumors but more often is cystic and solid |
How do serous papillary carcinoms vary from borderline tumors | there is stromal invasion with serous papillary carcinomas |
what is the most common malignancy of the ovary | serous papillary carcinoma |
What is the hallmark of mucinous tumors | columnar cells filled with nucin |
What is it called when women present with abdomens filled with mucin | pseudomyxoma peritoneii (jelly belly) |
What endometrial tumor is composed of clear cytoplasm and nuclei that protrude (hobnail) from the apex of the columnar cell | clear cell tumors |
What is the hallmark of Brenner tumors | islands of urothelial/transitional cells |
You find a tumor that is in the ovary and is composed of hair, sebum, and some poorly formed teeth. What is it? | Mature teratoma |
Which is more solid mature or immature teratomas | immature |
What is the ovarian counterpart to the testicular seminoma | dysgerminoma |
What tumor has the histologic finding of Schiller Duvall Bodies | Yolk Sac Tumor |
what does the yolk sac tumor of the ovary secrete | alpha fetal protein |
How do Chroiocarcinomas spread | hematogenously |
what do Chroiocarcinomas produce | B-HCG |
what are the three most common sex cord stromal tumors of the ovaries | Fibroma, Granulosa Cell Tumor, and Sertoli-Leydig cell tumor |
What is Meig's Syndrome | pleural effusions, ascites, and an ovarian mass (usually fibroma) |
What tumor has cells that resembles coffee beans | Granulosa Cell Tumor |
What is a Krukenberg tumor | bilateral enlargement of the ovaries due to metastatic signet ring carcinoma from the gastrointestinal tract |