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Hormone
T3, T4
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Hormone
Calcitonin
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Endocrine Hormones
List of hormones, target organs, triggers, effects, etc.
| Hormone | Secreted by | Trigger | Target Tissue | Effects | Too Much | Too Little |
|---|---|---|---|---|---|---|
| T3, T4 | Thyroid | TSH secreted by anterior pituitary gland in response to low T3, T4 serum levels | All body tissue | Increased availability of beta receptors, Controls: Metabolism, Caloric use, O2 consumption, CHO metabolism, Fat metabolism, Protein catabolism, Growth, Cell differentiation, Brain and CNS activity | Hyperthyroid, Graves, Thyroid Storm | Hypothyroid, Myxedema Coma |
| Calcitonin | Thyroid | High serum calcium | Kidneys, bone | Decreased serum calcium via: Inhibition of release of calcium, from bones/ bone resorption, Increased calcium storage in bone, Increased renal excretion of calcium | n/a | n/a |
| PTH | Parathyroid glands | Low serum calcium | Bone, kidneys, small intestine | Increased serum calcium via: Stimulation of bone resorption and inhibition of bone formation, Increased renal calcium absorption, Increased renal conversion of Calcidiol to Vitamin D, Increased calcium reabsorption from the GI tract | Hyperparathyroid, hypercalcemia | Hypoparathyroid, Hypocalcemia |
| Aldosterone | Adrenal cortex | ACTH from the anterior pituitary, renin-angiotensin, or high serum K | Kidneys | Sodium and water retention, Potassium excretion | Hyperaldosterone, Conn's | Addison's (in combination with Cortisol and Androgen decrease) |
| Androgen | Adrenal cortex | ACTH secreted from anterior pituitary | Organs associated with secondary sex characteristics: breasts, vocal cords, anything not needed for reproduction | Development of non-reproductive sex characteristics | Adrenal hyperplasia, Gonadocorticoid excess | Addison's (in combination with Cortisol and Androgen decrease) |
| Cortisol | Adrenal cortex | Hypothalamus releases CRH which triggers the anterior pituitary to release ACTH which acts on the adrenal cortex | All body tissues that use glucose | Glucose synthesis, Protein catabolism, Sodium and water retention, Potassium excretion, Inhibition of inflammatory response, Inhibition of immune response, Supports stress response/ creates feelings of well-being, Increases HCL in the stomach, Increases c | Cushings | Addison's (in combination with Cortisol and Androgen decrease) |
| Epinephrine/ Norepinephrine | Adrenal medulla | CNS triggers: Postural changes, Anxiety, Exercise, Increased intra- abdominal pressure, May be spontaneous | Flight or fight mechanism, Cardiac, Respiratory, CNS | Increased: Flight or fight, Heart rate, Respirations, BP, Vasoconstriction, Cardiac output, CNS action, Metabolism of glycogen to glucose | Pheochromocytoma | na |
| Growth Hormone (GH) | Anterior pituitary | (blank) | Long bones, soft tissue | Growth | Adults- acromegaly, Kids- gigantism | Adults- none, Kids- dwarfism |
| Anti-diuretic Hormone (ADH) | Posterior pituitary | Increased serum osmolality | Kidneys | Increased water reabsorption from renal tubules, Water retention, Decreased aldosterone, Decreased sodium absorption (hyponatremia), Vasoconstriction | SIADH | Diabetes Insipidus (DI) |
Created by:
ebadger
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